Yazar "Demirbaş, Neslihan" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
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Design, synthesis and antimicrobial activities of some azole derivatives
Başoğlu, Serap; Yolal, Meltem; Demirci, Serpil; Demirbaş, Neslihan; Bektaş, Hakan; Karaoğlu, Şengül Alpay (2013)Three new 1,3,4-oxadiazole, 1,3-thiazolidine and 1,2,4-triazole derivatives were obtained starting from furan-2-carbohydrazide. Then, 1,2,4-triazole compound was converted to the corresponding Mannich bases using several ... -
Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives
Başoğlu, Serap; Demirbaş, Ahmet; Ülker, Serdar; Alpay-Karaoğlu, Şengül; Demirbaş, Neslihan (Elsevier France-Editions Scientifiques Medicales Elsevier, 2013)The treatment of 7-ACA with 4-substituted benzensulfonyl chlorides afforded the compounds containing 4-nitro/aminophenyl sulfonylamino moiety in the cephalosporanic acid skeleton (2, 4). the synthesis of the cephalosporanic ... -
The electrochemical and spectroelectrochemical properties of metal free and metallophthalocyanines containing triazole/piperazine units
Demirbaş, Ümit; Akyüz, Duygu; Mermer, Arif; Akçay, Hakkı Türker; Demirbaş, Neslihan; Koca, Atıf; Kantekin, Halit (Pergamon-Elsevier Science Ltd, 2016)The synthesis and characterization of novel peripherally tetra [1,2,4]-triazole substituted metal-free phthalocyanine and its metal complexes (Zn(II), Ni(II), Pb(II), Cu(II) and Fe(II)) and the investigation of electrochemical ... -
Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities
Menteşe, Meltem Yolal; Bayrak, Hacer; Uygun, Yıldız; Mermer, Arif; Ülker, Serdar; Karaoğlu, Şengül Alpay; Demirbaş, Neslihan (Elsevier France-Editions Scientifiques Medicales Elsevier, 2013)Norfloxacin was converted to 7-(4-amino-2-fluorophenyl)piperazin derivative (2) via the formation of nitro compound. the synthesis of the norfloxacin derivatives containing 1,3-thiazole or 1,3-thiazolidin moiety was performed ... -
Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies
Mermer, Arif; Faiz, Özlem; Demirbaş, Ahmet; Demirbaş, Neslihan; Alagumuthu, Manikandan; Arumugam, Sivakumar (Academic Press Inc Elsevier Science, 2019)A series of new 1,2,4-triazole and 1,3,4-oxadiazole derivatives was obtained via several steps sequential reactions of phenyl piperazine. Then, these compounds were converted to the corresponding fluoroquinolone hybrids ... -
Syntheses and biological activities of new hybrid molecules containing different heterocyclic moieties
Ceylan, Şule; Bektaş, Hakan; Bayrak, Hacer; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay; Ülker, Serdar (Wiley, 2013)4-Aryl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-(thi)oles 5-7, obtained starting from nicotinic acid hydrazide were converted to the corresponding Mannich bases 12-24 by the reaction with several heterocyclic amines in the ... -
Synthesis of some heterofunctionalized penicillanic acid derivatives and investigation of their biological activities
Demirci, Serpil; Demirbaş, Ahmet; Ülker, Serdar; Alpay-Karaoğlu, Şengül; Demirbaş, Neslihan (Wiley-V C H Verlag Gmbh, 2014)6-Substituted amino-penicillanic acid esters were synthesized starting with 6-apa. the compounds containing a 1,3-thiazole- or 1,3-thiazolidinone nucleus linked to the penicillanic acid skeleton via a hydrazino linkage ... -
Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities
Bayrak, Hacer; Demirbağ, Ahmet; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (Elsevier, 2009)5-Pyridin-4-yl-1,3,4-oxadiazole-2-thiol (2) was obtained from the reaction of isonicotinic acid hydrazide with carbon disulfide in basic media and converted into 4-amino-5-pyridin-4-yl-4H-1,2,4-triazole-3-thiol (5) by the ... -
Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities
Bayrak, Hacer; Demirbaş, Ahmet; Karaoğlu, Şengül Alpay; Demirbaş, Neslihan (Elsevier, 2009)4-Phenyl-5-pyridin-4-yl-4H-1,2,4-triazole-3-thiol (3) was obtained in basic media via the formation of 2-isonicotinoyl-N-phenylhydrazinecarbothioamide (2), and converted to some alkylated derivatives (4a,b) and Mannich ... -
Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities
Demirbaş, Ahmet; Şahin, Deniz; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (Elsevier, 2009)4-Amino-2-[(5-arylamino-4,5-dihydro-1,3,4-thiadiazol-2-yl)methyl]-5-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-ones (3a-c) were obtained in acidic media via the formation of 2-[(4-amino-3-aryl-5-oxo-4,5-dihydro-1H-1 ...