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Toplam kayıt 27, listelenen: 1-10
Periodontitis exacerbates the renal degenerative effects of obesity in rats
(Wiley, 2021)
Background/objectives Obesity and periodontitis are systemic subclinical inflammatory diseases with established negative renal effects. The aim of this animal study was to thoroughly investigate the possible effects of ...
The hepatoprotective potential of resveratrol in an experimental model of ruptured abdominal aortic aneurysm via oxidative stress and apoptosis
(Wiley, 2021)
The mortality rate in ruptured abdominal aortic aneurysms can today be reduced through cardiovascular surgery. However, ischemia and reperfusion-induced tissue damage develop due to aortic cross-clamping applied during ...
Influences of periodontitis on hippocampal inflammation, oxidative stress, and apoptosis in rats
(Wiley, 2021)
Background and aim The hippocampus, which has a central role in cognitive and behavioral activities, is one of the most sensitive parts of the brain to systemic inflammatory diseases. This animal study aims to comprehensively ...
p-Coumaric acid alleviates cisplatin-induced ovarian toxicity in rats
(Wiley, 2021)
Objective The therapeutic value of cisplatin (CDDP) as an anticancer drug is limited by its ovo-otoxicity. The effect of natural phenolic acids in the prevention of many diseases related to oxidative stress has been reported. ...
Effects of gadodiamide and gadoteric acid on lung tissue: A comparative study
(Wiley, 2022)
We set out to investigate the effects of gadodiamide and gadoteric acid, used for magnetic resonance imaging, on the lungs. In this study, 32 male Sprague Dawley rats were used. These were allocated into four groups; The ...
Effects of bone marrow-derived mesenchymal stem cells on doxorubicin-induced liver injury in rats
(Wiley, 2022)
Doxorubicin (DOX) is a potent chemotherapeutic agent and has toxic effects on various organs, including the liver. In the current study, we aimed to investigate the effects of bone-marrow-derived mesenchymal stem cell ...
Comparison of effects of dexmedetomidine and amifostine against X-ray radiation-induced parotid damage
(Springer, 2022)
Radiotherapy can be employed as a therapeutic modality alone in the early stages of cancer and is used together with other treatments such as surgery and chemotherapy in more advanced stages. However, exposure to ionizing ...
Design and synthesis of benzimidazole derivatives as apoptosis-inducing agents by targeting Bcl-2 protein
(Springer, 2022)
Bcl-2, an anti-apoptotic protein, is a well-known and appealing cancer therapy target. Novel series of benzimidazole derivatives were synthesized and tested for their activity as Bcl-2 inhibitors on T98G glioblastoma, PC3 ...
The role of vaccinium myrtillus in the prevention of renal injury in an experimental model of ruptured abdominal aortic aneurysm
(Soc Brasil Cirurgia Cardiovasc, 2020)
Objective: To examine the biochemical and histopathological renal effects of ischemia/reperfusion (I/R) injury using a ruptured abdominal aortic aneurysm (RAAA) model in rats and to investigate the potential protective ...
Tea grape reduces abdominal aortic occlusion-induced lung injury
(Soc Brasil Cirurgia Cardiovasc, 2020)
Introduction: Ischemia-associated mortality caused by aortic cross-clamps, as in ruptured abdominal aorta aneurysm surgeries, and reperfusion following their removal represent some of the main emergency conditions in ...