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Toplam kayıt 95, listelenen: 41-50
A novel therapeutics agent: antioxidant effects of hydroxylfasudil on rat kidney and liver tissues in a protamine sulphate-induced cystitis rat model; preliminary results
(Taylor & Francis Ltd, 2018)
Cystitis is defined as an inflammation of the bladder caused by a bacterial infection, and it can be dangerous and painful when it spreads through the internal organs. in this study, antioxidant effects of hydroxylfasudil ...
Protective effect of an L-type calcium channel blocker, amlodipine, on paracetamol-induced hepatotoxicity in rats
(Sage Publications Ltd, 2018)
Paracetamol (P), one of the most popular and commonly used analgesic and antipyretic agents, causes hepatotoxicity in overdoses. Amlodipine (AML), an L-type calcium channel blocker, has been shown to have anti-inflammatory ...
Effects of gadolinium-based MRI contrast agents on liver tissue
(Wiley, 2018)
BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...
Whortleberry protects kidney against the cisplatin-induced nephrotoxicity: an experimental study
(Taylor & Francis Ltd, 2018)
Purpose: This study investigated the antioxidant effects of whortleberry against cisplatin-induced nephrotoxicity in rats.Material and methods: This study included 48 female Sprague-Dawley rats weighing 263.688.29g. the ...
Pathological findings observed in the kidneys of postnatal male rats exposed to the 2100 MHz electromagnetic field
(Elsevier Science Inc, 2018)
Background. the widespread use by young people of modern communication devices such as mobile phones means that they are particularly exposed to electromagnetic fields (EMF) and other problems. However, few studies have ...
The effect of gadolinium-based contrast agents on rat testis
(Wiley, 2018)
Previous studies have reported that repeated administrations of linear gadolinium-based contrast agents lead to their accumulation in the brain and other tissues in individuals with normal renal functions. the purpose of ...
Effects of infliximab against methotrexate toxicity in splenic tissue via the regulation of CD3, CD68, and C200R in rats
(Karger, 2018)
Methotrexate (MTX), which has been used in clinical practice for approximately 70 years, is still widely employed in the treatment of rheumatoid arthritis (RA), psoriasis, and cancer. Although MTX toxicity causes nephrotoxicity, ...
Changes in testicular morphology and oxidative stress biomarkers in 60-day-old Sprague Dawley rats following exposure to continuous 900-MHz electromagnetic field for 1 h a day throughout adolescence
(Pergamon-Elsevier Science Ltd, 2018)
The purpose of this study was to investigate the 60-day-old male rat testis following exposure to continuous 900-megahertz (MHz) electromagnetic field (EMF) throughout the adolescent period using histopathological and ...
The protective effect of astaxanthin against cisplatin-induced nephrotoxicity in rats
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2018)
Purpose: the aim of this experimental study was to investigate the antioxidant effects of astaxanthin against cisplatin-induced nephrotoxicity in rats. Methods: Forty-eight male Sprague-Dawley rats weighing 264.83 +/- 7.39 ...
The effect of white tea on serum TNF-alpha/NF-kappa B and immunohistochemical parameters in cisplatin-related renal dysfunction in female rats
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)
Objective: Nephrotoxicity is the most important side effect of the antineoplastic drug cisplatin, thereby restricting its use. the aim of this study was to investigate the protective effects of white tea infusions(WT) ...