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Toplam kayıt 25, listelenen: 1-10
The protective effects of perindopril against acute kidney damage caused by septic shock
(Springer/Plenum Publishers, 2021)
Acute kidney injury (AKI) resulting from septic shock caused by sepsis is an important health problem encountered at rates of 55-73%. Increasing oxidative stress and inflammation following sepsis is a widely observed ...
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats
(Taylo & Francis Ltd., 2021)
Acute kidney injury (AKI) is observed in nearly 60% of patients undergoing cisplatin (CP) therapy. The aim of this study was to reveal the potential effects of apelin-13 (AP-13) in the prevention of CP-induced renal toxicity, ...
The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis
(Pergamon-Elsevier Science Ltd., 2021)
Aim: Early and prompt treatment of sepsis by effective antibiotics against susceptible organisms may be lifesaving. However, increased antibiotic resistance and side effects of chemotherapeutic agents limiting their ...
Periodontitis exacerbates the renal degenerative effects of obesity in rats
(Wiley, 2021)
Background/objectives Obesity and periodontitis are systemic subclinical inflammatory diseases with established negative renal effects. The aim of this animal study was to thoroughly investigate the possible effects of ...
Influences of periodontitis on hippocampal inflammation, oxidative stress, and apoptosis in rats
(Wiley, 2021)
Background and aim The hippocampus, which has a central role in cognitive and behavioral activities, is one of the most sensitive parts of the brain to systemic inflammatory diseases. This animal study aims to comprehensively ...
Syringic acid protects against thioacetamide-induced hepatic encephalopathy: Behavioral, biochemical, and molecular evidence
(Elsevier, 2021)
The objective of this study was to elucidate the effects of syringic acid on thioacetamide-induced hepatic encephalopathy which is a complex serious syndrome with neuropsychiatric abnormalities related to acute liver ...
p-Coumaric acid alleviates cisplatin-induced ovarian toxicity in rats
(Wiley, 2021)
Objective The therapeutic value of cisplatin (CDDP) as an anticancer drug is limited by its ovo-otoxicity. The effect of natural phenolic acids in the prevention of many diseases related to oxidative stress has been reported. ...
Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats
(Taylor & Francis Ltd., 2021)
The aim of the present study was to evaluate the protective effect of gallic acid (GA) against cisplatin (CDDP)-induced ovarian toxicity, for the first time. The ovarian damage was generated with CDDP (5 mg/kg) intraperitoneally ...
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
(Taylor & Francis Ltd., 2022)
Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ...
The protective effects of trimetazidine against ovary ischemia-reperfusion injury via the TLR4/Nf-kB signal pathway
(Wiley, 2022)
Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia, irreversible damage to ovarian functions and infertility. In this process, there is no approved medical treatment that can reduce the ...