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Toplam kayıt 123, listelenen: 51-60
Inhibition of methotrexate induced toxicity in the adult rat spleen by adalimumab
(Taylor & Francis Ltd., 2022)
Methotrexate (MTX) has been in use for the treatment of rheumatoid arthritis (RA), psoriasis, and cancer since 1948. Its toxic side effects on tissues and organs have been well documented but splenotoxicity has not been ...
The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation
(Verduci Editore, 2022)
OBJECTIVE: Sepsis is responsible for more than 5 million deaths worldwide every year. The purpose of this study was to use amifostine to reduce acute kidney injury developing as a result of sepsis. MATERIALS AND METHODS: ...
Histopathological evaluation of the effects of dexmedetomidine against pituitary damage ınduced by X-ray irradiation
(Taylor & Francis Ltd., 2022)
Background: The present study, aimed to investigate the potential negative effects of x-ray radiation and the effects of the α2-adrenergic receptor agonist dexmedetomidine on the pituitary gland. Methods: Twenty-four ...
The effects of TNF-alpha inhibitors on carbon tetrachloride-induced nephrotoxicity
(Taylo & Francis Ltd., 2021)
Objectives: Carbon tetrachloride (CCl4), employed in various industrial fields, can cause acute damage in renal tissues. This study investigated the therapeutic effect of the TNF-alpha inhibitor Infliximab on TGF-beta and ...
Comparison of linear versus macrocyclic gadolinium chelates in rat skeletal muscle
(2022)
OBJECTIVE: We investigated the effects on skeletal muscle of gadolinium based linear and macrocyclic radiocontrast agents
applied at experimental intervals using histopathological methods.
METHODS: Thirty-two male ...
The protective effects of red ginseng and amifostine against renal damage caused by ionizing radiation
(2022)
This study aimed to elucidate the effects of amifostine (ethyol) (AM), a synthetic radioprotector, and red ginseng (RG), a natural radioprotective agent, against the toxic effect of ionizing radiation (IR) on kidney tissues ...
Effects of exposure to 2100 MHz GSM-like radiofrequency electromagnetic field on auditory system of rats
(Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2017)
Introduction: the use of mobile phones has become widespread in recent years. Although beneficial from the communication viewpoint, the electromagnetic fields generated by mobile phones may cause unwanted biological changes ...
The effects of curcumin on wound healing in a rat model of nasal mucosal trauma
(Hindawi Ltd, 2017)
We explored the effects of topical curcumin on the healing of nasal mucosal wounds. A total of 32 Sprague-Dawley Albino rats were randomized in equal numbers into four groups, and unilateral nasal wounds were created using ...
Lasting hepatotoxic effects of prenatal mobile phone exposure
(Taylor & Francis Ltd, 2017)
Objective: in this study, the livers of rats born to mothers exposed to electromagnetic field (EMF) were examined 60 days postpartum for biochemical and histopathological changes.Methods: Pregnant rats were exposed to ...
The therapeutic effect of thymoquinone on acoustic trauma-induced hearing loss in rats
(Springer, 2017)
Thymoquinone has antioxidant properties. We hypothesized that thymoquinone may prevent or alleviate hearing loss induced by acoustic trauma. We aimed to study thymoquinone's effect on hearing function with distortion-product ...