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Toplam kayıt 48, listelenen: 1-10
Topiramate ameliorates abdominal aorta cross-clamping induced liver injury in rats
(Wolters Kluwer Medknow Publications, 2014)
Background and Aim: Ischemia/reperfusion (I/R) injury in the liver occurs after a prolonged period of ischemia followed by restoration of hepatic blood perfusion. During the surgery of abdominal aorta, I/R injury causes ...
Adalimumab ameliorates abdominal aorta cross clamping which induced liver injury in rats
(Hindawi Ltd, 2014)
The aim of this study was to investigate the possible protective effects of adalimumab (ADA) on cell damage in rat liver tissue during ischemia/reperfusion (I/R) injury of infrarenal abdominal aorta. Thirty male Wistar-albino ...
Influence of infliximab pretreatment on ischemia/reperfusion injury in rat intestine
(Via Medica, 2014)
The Pringle maneuver is used in hepatic surgery to prevent blood loss but is associated with ischemia-reperfusion injury. To investigate the effect of infliximab on inflammation and apoptosis in rat intestinal mucosa during ...
Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats
(Shenyang Editorial Dept Neural Regeneration Res, 2015)
Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle cerebral artery occlusion were intraperitoneally ...
The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats
(Acta Cirurgica Brasileira, 2016)
PURPOSE: To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats. METHODS: Pregnant rats in the experimental group were exposed to radiation ...
The acute effects of preoperative ozone theraphy on surgical wound healing
(Acta Cirurgica Brasileira, 2016)
PURPOSE: To investigate the effects of preoperative rectal ozone insufflation on surgical wound healing over the proinflammatory cytokines and histopathological changes. METHODS: Twenty one rabbits were divided into 3 ...
The protective effect of infliximab on cisplatin-induced intestinal tissue toxicity
(Verduci Publisher, 2014)
OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. the aim of this study was to investigate the protective effects of ...
Effect of infliximab against cisplatin-induced nephrotoxicity
(Saudi Med J, 2014)
Objectives: To investigate whether infliximab (Ib), an inhibitor of tumor necrosis factor alpha (TNF-alpha), prevents cisplatin (Cis)-induced nephrotoxicity. Methods: the study was performed in the Department of Internal ...
Topiramate has protective effect on renal injury
(Comenius Univ, 2015)
Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage. ...
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
(Wolters Kluwer Medknow Publications, 2015)
Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ...