Yazar "Tok, Fatih" için Fen Edebiyat Fakültesi listeleme
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Synthesis of novel thiosemicarbazone derivatives as antidiabetic agent with enzyme kinetic studies and antioxidant activity
Tok, Fatih; Küçükal, Bahar; Baltaş, Nimet; Tatar Yılmaz, Gizem; Koçyiğit Kaymakçıoğlu, Bedia (Taylor & Francis Ltd., 2022)Novel thiosemicarbazone derivatives were synthesized via condensation reactions between the corresponding thiosemicarbazides and 4-(methylsulfonyl)acetophenone. The chemical structures of all compounds were elucidated by ... -
Synthesis, biological evaluation and in silico studies of new pyrazoline derivatives bearing benzo[d]thiazol-2(3H)-one moiety as potential urease inhibitors
Tok, Fatih; Baltaş, Nimet; Tatar, Gizem; Koçyiğiy Kaymakçıoğlu, Bedia (Wiley, 2022)Novel pyrazoline derivatives containing benzo[d]thiazol-2(3H)-one moiety were synthesized and screened for their inhibitory properties against urease, a clinically important metabolic enzyme. In vitro enzyme inhibition ... -
Synthesis, in-vitro inhibition of cholinesterase and in silico studies of new hydrazide-hydrazones derived from Clopidogrel
Tok, Fatih; Çelikçi, Taner; Acar, Ahmet Beytullah; Baltaş, Nimet; Başoğlu, Faika; Karakuş, Sevgi (Elsevier, 2024)Due to the lack of an effective treatment for Alzheimer's disease, there is a need for the development of new and effective compounds. The synthesis of some new hydrazone derivatives (TA1-TA14) based on Clopidogrel bisulfate ...