Ara
Toplam kayıt 12, listelenen: 1-10
Synthesis of some new hybride molecules containing several azole moieties and investigation of their biological activities
(Maik Nauka/Interperiodica/Springer, 2014)
1,2,4-Triazole-3-one prepared from tryptamine was converted to the corresponding carbothioamides by several steps. Their treatment with ethyl bromoacetate or 4-chlorophenacyl bromide produced the corresponding 5-oxo-1,3- ...
Microwave-promoted synthesis and biological activity of some 2-hetarylmethyl-4-(4-hetarylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one derivatives
(Springer, 2015)
A series of fused and non-fused 1,2,4-triazole derivatives were prepared starting from ethyl 4-[1-(2-ethoxy-2-oxoethyl)-3-methyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]benzoate. Firstly, both ethyl ester groups were ...
Synthesis and study of alpha-glucosidase inhibitory, antimicrobial and antioxidant activities of some benzimidazole derivatives containing triazole, thiadiazole, oxadiazole, and morpholine rings
(Springer, 2015)
A new series of 2-(4-bromobenzyl)- and 2-(4-fluorobenzyl)-1H-benzimidazole derivatives containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and morpholine rings has been synthesized. the structures of the newly ...
Microwave-assisted and conventional synthesis of novel antimicrobial 1,2,4-triazole derivatives containing nalidixic acid skeleton
(Walter de Gruyter Gmbh, 2016)
Carbothioamides 4a,b, obtained from nalidixic acid, were converted to the corresponding 1,3-thiazolidine derivatives 5a,b by cyclocondensation with 2-bromo-1-(4-chlorophenyl) ethanone. Treatment of 4a,b with base afforded ...
Microwave assisted synthesis and antimicrobial activity evaluation of new heterofunctionalized norfloxacine derivatives
(Bentham Science Publ Ltd, 2016)
The synthesis of new hybrid compounds containing several heterocyclic groups namely norfloxacine, 1,2,4-triazole, 1,3,4-oxadiazole, piperazine, morpholine, thiomorpholine, 1,3,4-thiadiazole etc. was performed by conventional ...
Novel microwave assisted synthesis and antimicrobial activity of new quinolone-hybrids
(Bentham Science Publ Ltd, 2016)
Background: Carbo(thio)amid derivatives 4a, 4b were obtained starting from nalidixic acid in three steps. the acidic treatment of compound 4a generated the corresponding 1,3,4-oxadiazole (5), while the compound 4a gave ...
Design and microwave-assisted synthesis of a novel Mannich base and conazole derivatives and their biological assessment
(Walter de Gruyter, 2021)
4-Amino-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (1) was converted to the corresponding Schiff base (2) by treatment with salicylaldehyde. 1,2,4-Triazoles were then converted to the corresponding Mannich bases containing ...
Conventional and microwave-assisted synthesis of novel 1,2,4-triazole derivatives containing tryptamine skeleton and evaluation of antimicrobial activity
(Bentham Science Publishing, 2021)
1,2,4-Triazole-3-one (3) obtained from tryptamine was transformed to the corresponding carbox(thio)amides via several steps (6a-d). Their reaction with sodium hydroxide performed the 1,2,4triazole derivatives (7a-d). ...
Conventional and microwave irradiated synthesis, biological activity evaluation of highly substituted indole-triazole hybrids
(Elsevier, 2022)
In the present study, a series of new indole-3-carbaldehyde embedded triazole derivatives have been synthesized. 4-{[(1E)-1H-indol-3-ylmethylidene]amino}-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (2) were converted to ...
Synthesis and antimicrobial activity of some new triazole bridged benzimidazole substituted phthalonitrile and phthalocyanines
(Editura Acad Romane, 2018)
In this study, some new phthalonitriles and metallophthalocyanines (Zn, Ni, Co, and Cu) containing triazole bridged benzimidazole moieties were synthesized starting from 2-(3-methylbenzyl)-1H-benzimidazole Newly synthesized ...
