Ara
Toplam kayıt 3, listelenen: 1-3
Microwave-assisted and conventional synthesis of novel antimicrobial 1,2,4-triazole derivatives containing nalidixic acid skeleton
(Walter de Gruyter Gmbh, 2016)
Carbothioamides 4a,b, obtained from nalidixic acid, were converted to the corresponding 1,3-thiazolidine derivatives 5a,b by cyclocondensation with 2-bromo-1-(4-chlorophenyl) ethanone. Treatment of 4a,b with base afforded ...
Novel microwave assisted synthesis and antimicrobial activity of new quinolone-hybrids
(Bentham Science Publ Ltd, 2016)
Background: Carbo(thio)amid derivatives 4a, 4b were obtained starting from nalidixic acid in three steps. the acidic treatment of compound 4a generated the corresponding 1,3,4-oxadiazole (5), while the compound 4a gave ...
Synthesis and antimicrobial activity of new piperazine-based heterocyclic compounds
(Walter de Gruyter Gmbh, 2017)
The hydrazide 5, that was obtained from -1-(4-fluorophenyl) piperazine (1), was converted to the cor-responding carbothioamides 6a-c by the reaction with alkyl(aryl) isothiocyanates. the synthesis of conazole analogs 10a-f ...