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Toplam kayıt 8, listelenen: 1-8
Microwave-assisted synthesis of new benzimidazole derivatives with lipase inhibition activity
(Taylor & Francis Ltd, 2014)
A practical protocol has been used for the synthesis of benzimidazoles. the reaction of iminoester hydrochlorides of phenylacetic with 4,5-dichloro-1,2-phenylenediamine under microwave irradiation leads to the benzimidazole ...
An efficient synthesis of benzimidazoles via a microwave technique and evaluation of their biological activities
(Springer Wien, 2013)
A simple and practical protocol was developed for the synthesis of benzimidazoles. the protocol uses iminoester hydrochloride which is very useful in the reaction with 4,5-dichloro-1,2-phenylenediamine under microwave ...
Synthesis and pharmacological activities of some new 2-[1-Heptyl-3-(4-methoxybenzyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl] acetohydrazide derivatives
(Walter de Gruyter Gmbh, 2014)
In the present investigation, the key intermediate acetohydrazide derivative 5 was synthesized starting from 3-(4-methoxybenzyl)-4-amino-4,5-dihydro-1,2,4-triazol-5-one (1) by a four-step reaction. Thiosemicarbazides 6a-f ...
Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives
(Maik Nauka/Interperiodica/Springer, 2014)
This study presents a synthesis of new series of some benzimidazole, bisbenzimidazole and perimidine derivatives via microwave technique, which, leads to the good product yields and short reaction times. the structure of ...
Synthesis and study of alpha-glucosidase inhibitory, antimicrobial and antioxidant activities of some benzimidazole derivatives containing triazole, thiadiazole, oxadiazole, and morpholine rings
(Springer, 2015)
A new series of 2-(4-bromobenzyl)- and 2-(4-fluorobenzyl)-1H-benzimidazole derivatives containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and morpholine rings has been synthesized. the structures of the newly ...
Microwave-assisted synthesis of some new coumarin derivatives including 1,2,4-triazol-3-one and investigation of their biological activities
(Springer, 2015)
By using the microwave technology, a new protocol has been developed for the synthesis of new coumarin derivatives including 1,2,4-triazol-3-one skeleton. This protocol proves to be efficient and environmentally friendly ...
Synthesis and evaluation of alpha-glucosidase and pancreatic lipase inhibition by quinazolinone-coumarin hybrids
(Springer, 2016)
A new series of 2-substituted quinazolin-4(3H)-one derivatives including coumarin nucleus has been synthesized and screened for their lipase and a-glucosidase inhibition properties. Among the synthesized compounds, ...
Design, synthesis, and biological evaluation of coumarin-triazole hybrid molecules as potential antitumor and pancreatic lipase agents
(Wiley-V C H Verlag Gmbh, 2017)
The design, synthesis, and investigation of antitumor and anti-lipase activities of some coumarin-triazole hybrid molecules are reported. the synthesis of these hybrid molecules was performed under microwave irradiation ...