Recep Tayyip Erdoğan Üniversitesi Kurumsal Akademik Arşivi
DSpace@RTEÜ, Recep Tayyip Erdoğan Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Unlocking the potential of nutmeg oil: A sustainable alternative for rainbow trout anesthesia in aquaculture
(Elsevier, 2025) Minaz, Mert; Er, Akif; Ak, Kübra; Serdar, Osman
In aquaculture, interest in natural anesthetic agents as alternatives to synthetic anesthetics has been steadily increasing. This is due to concerns over residue accumulation, environmental impact, and growing demand for sustainable practices. Within this context, the present study focused on the anesthetic effects of nutmeg essential oil at three different concentrations in rainbow trout (Oncorhynchus mykiss, 94.42 ± 23.9 g): low (400 µL/L), medium (600 µL/L), and high (800 µL/L). Induction and recovery times were recorded, and samples were collected at 0, 2, 4, and 8 hours post-anesthesia for antioxidant, cortisol, and hematological analyses. Additionally, gill tissues were sampled immediately after anesthesia for histological examination. While the induction time for the low concentration exceeded 3 minutes, the induction and recovery times for the other concentrations ranged within acceptable limits (3 min for induction and 5 min for recovery). Blood parameters exhibited an increasing trend until the 4th hour post-anesthesia, peaking at the 2nd hour, before returning to control levels by the 4th hour. Histological evaluation revealed healthy gill tissues in the control and low-concentration group (400 µL/L), whereas hyperplasia was observed in the medium (600 µL/L) and high-concentration (800 µL/L) groups. Antioxidant enzyme activity (superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA), and glutathione peroxidase (GSH-Px)) indicated potential oxidative stress at the high anesthetic concentration. Similarly, cortisol levels were higher at the high concentration, with plasma cortisol showing a slight initial increase followed by a return to normal levels over time. In conclusion, this study highlights that nutmeg oil at a concentration of 600 µL/L may serve as a promising natural alternative to synthetic anesthetics in aquaculture. However, future studies should include a synthetic anesthetic as a control to allow for direct comparisons and a more comprehensive evaluation of its efficacy and physiological effects.
Efficiency analysis using the machine learning algorithms: model development and verification
(Springer, 2025) Soydaş, Şafak Sönmez; Kalkan, Yusuf; Çam, Alper Veli; Barut, Abdulkadir
Recently, machine learning (ML) algorithms have been employed intensively in the field of finance as in all sectors. The issues such as financial distress prediction, bank credit risk calculation, etc., have been analyzed using ML algorithms. This study aimed to determine firm performance with the data envelopment analysis (DEA) method, sensitivity analysis, and ML algorithms and analyze the efficiency of companies via artificial neural networks (ANNs), support vector machines (SVMs), and logistic regression (LR) classification algorithms. In the study, first, 10 financial ratios were categorized into two parts, such as output and input, and efficiency scores were determined in MS Excel software. The obtained scores were included in the ML algorithm as a categorical dependent variable. Secondly, the data were extracted and included in the analysis software as 80% training and 20% test data, and the accuracy of ML algorithms was tested. Lastly, a comparative analysis of the estimation and classification algorithms of active and inactive companies was conducted. As a result of the analysis, the best classification prediction was seen as the ANN algorithm. SVM and LR algorithms also made an acceptable level of classification prediction. It was expected that the study would have contributed to the literature in terms of testing the companies whose efficiency scores were determined by the DEA method with ML techniques and determining which technique was more successful.
MoS2-WS2 decorated carbon nanotubes amplified electro-nanosensor for label-free voltammetric detection of DNA
(Elsevier, 2025) Bal Altuntaş, Derya; Sanko, Vildan; Kuralay, Filiz
The development of functional interfaces for healthcare applications is in great demand to perform sensitive and reliable testing. For this purpose, in the present study, the use of transition metal dichalcogenides (TMDCs) combined with carbon nanotubes modified pencil graphite electrode (PGE) was demonstrated for fish sperm double-stranded deoxyribonucleic acid (fsDNA) detection. The advanced system consisted of molybdenum disulfide (MoS2), tungsten disulfide (WS2), and multi-walled carbon nanotubes (MWCNTs), which exhibited superior and fascinating electrochemical properties on PGE as a result of synergetic effect occurred between the materials. The MoS2-WS2-MWCNTs incorporated PGE (MoS2-WS2-MWCNTs/E) was characterized by scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray diffraction (XRD) analysis, and electrochemical techniques. The elemental composition of the sensing platform was monitored with energy-dispersive X-ray spectroscopy (EDS). Specific parameters, including the amount of components in the hybrid material were optimized. MoS2-WS2-MWCNTs/E presented a good linear range for fsDNA between 0.1 and 50mgL−1 with a low detection limit of 0.05 mg L−1 by using the differential pulse voltammetry (DPV) technique. The detection performance of the resulting electrode was compared with the responses of MoS2-MWCNTs/E and WS2-MWCNTs/E as well. This sensing platform establishes the use of dichalcogenides-carbon nanotubes-based material for facile, sensitive, and reproducible sensing applications.
Correction to: The prognostic impact of Her2 status in early triple negative breast cancer: a Turkish Oncology Group (TOG) study (Scientific Reports, (2024), 14, 1, (23556), 10.1038/s41598-024-75293-5)
(Nature Research, 2025) Özyurt, Neslihan; Alkan, Ali; Gülbağcı, Burcu; Seyyar, Mustafa; Aşık, Esra; Şahbazlar, Mustafa; Aydın, Esra; Doğan, Mutlu
Correction to: Scientific Reportshttps://doi.org/10.1038/s41598-024-75293-5, published online 09 October 2024 The original version of this Article contained an error in the spelling of the author Esra Aşık which was incorrectly given as Esra Aydın. The original Article has been corrected.
Comparison of methods for detecting mandibular lingula and can antilingula be used in lingula mandibula detection?
(BioMed Central Ltd, 2025) Balaban, Emre; Köse, Taha Emre; Günaçar, Dilara Nil; Naralan, Muhammed Enes; Gonca, Merve
Objective: The aim of this study is to evaluate the relationship between anatomical reference points used during orthognathic surgery and to minimize the risks of iatrogenic neurovascular damage. Materials and methods: This retrospective study included cone-beam computed tomography (CBCT) images involving the mandible from patients who visited Recep Tayyip Erdoğan University Faculty of Dentistry between January 2018 and September 2023. The age range of the included individuals was set between 18 and 80 years. Horizontal and vertical distances between mandibular anatomical structures, such as the lingula mandibula (LM), mandibular foramen (MF), antilingula (AL), and surrounding structures were measured using CBCT software. Individuals with intraosseous pathology, insufficient image quality, or a history of surgical/orthodontic treatment were excluded from the study. Results: A total of 240 hemimandibles from 120 patients were analyzed (55.83% female, 44.17% male; mean age: 46.78 ± 15.30 years). Significant differences were identified in LM positions according to different AL types. The LM was found to be more inferior and posterior relative to hill and ridge type ALs, while it was more anterior relative to plateau type ALs. In 26.25% of mandibular rami, AL was not detected. Conclusion: The position of the AL can serve as a guide in determining the osteotomy line during inferior vertical ramus osteotomy (IVRO). However, relying solely on AL as a reference point may increase the risk of inferior alveolar nerve (IAN) injury. Preoperative tomographic evaluations to determine the relationships among LM, MF, and AL can provide a safer approach in surgical planning, reduce complications, and help protect neurovascular structures.
