Yazar "Mercantepe, Filiz" için listeleme
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Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury
Mercantepe, Filiz; Mercantepe, Tolga; Topçu, Atilla; Yılmaz, Adnan; Tümkaya, Levent (Springer, 2018)Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 years has yet been discovered. This ... -
Protective effects of beta glucan in brain tissues of post-menopausal rats: a histochemical and ultra-structural study
Selli, Jale; Ünal, Deniz; Mercantepe, Filiz; Akaras, Nurhan; Kabayel, Rabia; Ünal, Bünyami; Atilay, Hilal (Taylor & Francis Ltd, 2016)Decline of estrogen during menopause has been associated with numerous significant changes that have been linked to many pathophysiological complications. in addition, ovarian hormone deficiency increases the production ... -
Protective effects of estrogen and bortezomib in kidney tissue of post-menopausal rats: an ultrastructural study
Mercantepe, Tolga; Ünal, Deniz; Selli, Jale; Mercantepe, Filiz; Ünal, Bünyamin; Karabıyık, Tuba Nur (Taylor & Francis Ltd, 2016)Purpose: Symptoms and disorders related to menopause and its associated estrogen deficiency have become a considerable health concern worldwide. Ovarian hormone depletion/estrogen deficiency can be usefully studied using ... -
Protective effects of tumor necrosis factor alpha inhibitors on methotrexate-induced pancreatic toxicity
Mercantepe, Tolga; Kalkan, Yıldıray; Tümkaya, Levent; Şehitoğlu, İbrahim; Mercantepe, Filiz; Yıldırmış, Sermet (Wroclaw Medical Univ, 2018)Background. Methotrexate (MTX), a folate antagonist, is commonly used in the treatment of many different types of cancer and inflammatory diseases, including pancreatic cancer, although its side effects on the pancreas ... -
The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats
Mercantepe, Tolga; Topçu, Atilla; Rakıcı, Sema; Tümkaya, Levent; Yılmaz, Adnan; Mercantepe, Filiz (Springer Heidelberg, 2019)The purpose of this study was therefore to investigate the effects of radiotherapy on the kidney and the potential use of agents such as N-acetylcysteine (NAC) in developing a future therapeutic protocol for radiation-induced ... -
Radioprotective effects of alpha 2-adrenergic receptor agonist dexmedetomidine on X-ray irradiation-induced pancreatic islet cell damage
Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz; Çiftel, Serpil; Çiftel, Sedat (Springer, 2023)Comprehensive epidemiological analyses conducted in the last 30 years have revealed a link between radiation and DM. We aimed to determine the effects of dexmedetomidine pretreatment on radiation-induced pancreatic islet ... -
The relationship between laboratory findings and mortality in COVID-19 patients requiring intensive care
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shows a wide clinical manifestation from asymptomatic infection to life-threatening respiratory failure. This study aimed to determine the ... -
Relationship between overnight dexamethasone suppression test and aging
Çiftel, Serpil; Mercantepe, Filiz (Cureus Inc., 2023)Background This study aims to investigate the relationship between suppressed cortisol levels measured after the 1-mg dexamethasone suppression test (DST) and age based on the hypothesis that aging can alter the activity ... -
Relationship between serum endocan levels and other predictors of endothelial dysfunction in obese women
Mercantepe, Filiz; Şahin, Serap Baydur; Cüre, Medine Cumhur; Karadağ, Zakir (Sage Publications, 2022)Endocan, or endothelial cell-specific molecule-1 (ESM-1), is a potential inflammatory marker implicated in endothelial dysfunction. The purpose of this study was to determine the correlation between serum endocan levels ... -
Relationship of vitamin B12 levels with different degrees of obesity and diabetes mellitus
Mercantepe, Filiz (Cureus Inc., 2023)Introduction: The potential influence of micronutrient status on obesity should be considered. Nevertheless, previous research examining the relationship between serum vitamin B12 levels and obesity has yielded inconclusive ...