Yazar "Özil, Musa" için listeleme
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A aonvenient synthesis of Bisbenzimidazoles from iminoester hydrochlorides Via Microwave Technique
Kahveci, Bahittin; Menteşe, Emre; Özil, Musa; Yılmaz, Fatih; Serdar, Mevlüt (Wiley-Blackwell, 2016)A simple and practical method has been developed for the synthesis of bisbenzimidazoles. Iminoester hydrochlorides of phenylacetic acids were used as intermediates in this reaction with 3,3'-diaminobenzidine under microwave ... -
Binuclear Cu(II), Ni(II) and Zn(II) complexes of hydrazone Schiff bases: Synthesis, spectroscopy, DFT calculations, and SOD mimetic activity
Zengin, Ali; Serbest, Kerim; Emirik, Mustafa; Özil, Musa; Menteşe, Emre; Faiz, Özlem (Elsevier, 2023)Two new salicylaldimine-based N-heterocyclic hydrazone ligands, N'-[(2-hydroxyphenyl) methylene]2-(2-phenyl-1H-benzimidazol-1-yl)acetohydrazone (H 2 L 1 ) and 2-[2-(3-chlorobenzyl)-1H-benzimidazol-1yl]-N'-[(2-(hydroxyimi ... -
Bioevaluation of synthetic pyridones as dual inhibitors of alpha-amylase and alpha-glucosidase enzymes and potential antioxidants
Saleem, Faiza; Khan, Khalid Mohammed; Ullah, Nisar; Özil, Musa; Baltaş, Nimet; Hameed, Shehryar; Salar, Uzma; Wadood, Abdul; Rehman, Ashfaq Ur; Kumar, Mukesh; Taha, Muhammad; Haider, Syed Moazzam (Wiley, 2022)Herein, a library of novel pyridone derivatives 1-34 was designed, synthesized, and evaluated for alpha-amylase and alpha-glucosidase inhibitory as well as antioxidant activities. Pyridone derivatives 1-34 were synthesized ... -
Determination of the protonation constants of triazole derivatives in non-aqueous solvents
İslamoğlu, Fatih; Kahveci, Bahittin; Özil, Musa; Akyüz, Emine; Menteşe, Emre; Ekinci, Arife Pınar (2009)Different 17 triazole derivatives were titrated with tetrabutylammonium hydroxide in four non-aqueous solvents (isopropyl alcohol, rert-butyl alcohol, N,N-dimethylformamide and acetonitrile), using Potentiometric method. ... -
Developing a scaffold for urease inhibition based on benzothiazoles: Synthesis, docking analysis, and therapeutic potential
Özil, Musa; Tuzcuoğlu, Özge; Emirik, Mustafa; Baltaş, Nimet (Wiley-V C Verlag GMBH, 2021)The synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzothiazole derivatives are reported. The title compounds in the two series, namely, 2-({5-[(benzothiazol-2-ylthio ... -
Diversely functionalized benzopyran scaffolds as potential lead candidates for treating Alzheimer's disease and diabetes
Naz, Fouzia; Seraj, Faiza; Taha, Muhammad; Özil, Musa; Salar, Uzma; Baltaş, Nimet; Ul-Haq, Zaheer; Tariq, Syeda Sumayya; Khan, Khalid Mohammed (Elsevier, 2024)The current study deals with the preparation of polyfunctional benzopyran derivatives 1–25, synthesized by the condensation of 2,4-dihydroxy benzophenone, substituted aldehydes, and malononitrile. These compounds were ... -
Ecofriendly solventless synthesis and reduction reaction of some triazole compounds and evaluation of their antimicrobial activity
Özil, Musa; Menteşe, Emre; Karaoğlu, Şengül Alpay; Kahveci, Bahittin (Taylor & Francis Inc, 2013)A number of triazole-3-one compounds have been synthesized, and reduction of the carbonyl group in the molecule has been carried out to give a corresponding hydroxyl group that possesses asymmetric carbon atom in good ... -
Efficient synthesis of 5-(substituted)benzyl-2,4-dihydro-3H-1,2,4-triazol- 3-ones using microwave irradiation
A growing body of literature has shown the effectiveness of using microwave irradiation in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new 5-aryl-2,4-dihydro-3H-1,2,4- ... -
An efficient synthesis of benzimidazoles via a microwave technique and evaluation of their biological activities
Kahveci, Bahittin; Menteşe, Emre; Özil, Musa; Ülker, Serdar; Ertürk, Murat (Springer Wien, 2013)A simple and practical protocol was developed for the synthesis of benzimidazoles. the protocol uses iminoester hydrochloride which is very useful in the reaction with 4,5-dichloro-1,2-phenylenediamine under microwave ... -
Efficient, rapid, and high-yield synthesis of aryl Schiff base derivatives and their in vitro and in silico inhibition studies of hCA I, hCA II, AChE, and BuChE
Özil, Musa; Balaydın, Halis T.; Doğan, Berna; Şentürk, Murat; Durdağı, Serdar (Wiley, 2024)This study reports a rapid and efficient synthesis of four novel aryl Schiff base derivatives. Biological activity and molecular modeling studies were conducted to evaluate the inhibitory effects of these compounds on human ... -
Emerging glyco-based strategies to steer immune responses
Anderluh, Marko; Berti, Francesco; Bzducha-Wrobel, Anna; Chiodo, Fabrizio; Colombo, Cinzia; Compostella, Federica; Durlik, Katarzyna; Ferhati, Xhenti; Holmdahl, Rikard; Jovanovic, Dragana; Kaca, Wieslaw; Lay, Luigi; Marinovic-Cincovic, Milena; Marradi, Marco; Özil, Musa; Polito, Laura; Reina-Martin, Jose Juan; Reis, Celso A.; Sackstein, Robert; Silipo, Alba; Svajger, Urban; Vanek, Ondrej; Yamamoto, Fumiichiro; Richichi, Barbara; van Vliet, Sandra J. (Wiley, 2021)Glycan structures are common posttranslational modifications of proteins, which serve multiple important structural roles (for instance in protein folding), but also are crucial participants in cell-cell communications and ... -
Hydrazinyl thiazole linked indenoquinoxaline hybrids: Potential leads to treat hyperglycemia and oxidative stress; Multistep synthesis, alpha-amylase, and antioxidant activities
Hameed, Shehryar; Khan, Khalid Mohammed; Salar, Uzma; Özil, Musa; Baltaş, Nimet; Saleem, Faiza; Qureshi, Urooj; Taha, Muhammad; Ul-Haq, Zaheer (Elsevier, 2022)A library of hydrazinyl thiazole-linked indenoquinoxaline hybrids 1-36 were synthesized via a multistep reaction scheme. All synthesized compounds were characterized by various spectroscopic techniques including EI-MS ... -
Imidazole-thiadiazole hybrids: A multitarget de novo drug design approach, in vitro evaluation, ADME/T, and in silico studies
Maqbool, Maryam; Solangi, Mehwish; Khan, Khalid M.; Özil, Musa; Baltaş, Nimet; Salar, Uzma; Tariq, Syeda S.; Haq, Zaheer Ul; Taha, Muhammad (Wiley, 2024)A library of imidazole-thiadiazole compounds (1–24) was synthesized to explore their therapeutic applications. The compounds were subjected to meticulous in vitro evaluation against α-glucosidase, α-amylase, acetylcholinesterase ... -
Indenoquinoxaline-phenylacrylohydrazide hybrids as promising drug candidates for the treatment of type 2 diabetes: In vitro and in silico evaluation of enzyme inhibition and antioxidant activity
Hameed, Shehryar; Saleem, Faiza; Özil, Musa; Baltaş, Nimet; Salar, Uzma; Ashraf, Sajda; Ul-Haq, Zaheer; Taha, Muhammad; Khan, Khalid Mohammed (Elsevier, 2024)Existing drugs that are being used to treat type-2 diabetes mellitus are associated with several side effects; thus, exploring potential drug candidates is still an utter need these days. Hybrids of indenoquinoxaline and ... -
Indole-pyridine carbonitriles: multicomponent reaction synthesis and bio-evaluation as potential hits against diabetes mellitus
Solangi, Mehwish; Khan, Khalid Mohammed; Ji, Xingyue; Özil, Musa; Baltaş, Nimet; Salar, Uzma; Khan, Alamgir; Ul-Haq, Zaheer; Meghwar, Herchand; Taha, Muhammad (2023)Background: Diabetes mellitus is a significant health disorder; therefore, researchers should focus on discovering new drug candidates. Methods: A series of indole-pyridine carbonitrile derivatives, 1-34, was synthesized ... -
Microwave-assisted and conventional synthesis of new phthalocyanines containing 4-(p-fluorophenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one moieties
Kahveci, Bahittin; Özil, Musa; Kantar, Cihan; Şaşmaz, Selami; Işık, Şamil; Köysal, Yavuz (Elsevier, 2007)New metal-free and metal (Zn, Ni, Cu and Co) phthalocyanines containing 4-(p-fluorophenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one moiety have been prepared from 1-(3,4-dicyanophenyl)-4-(p-fluorophenyl)-3-methyl-4,5- ... -
Microwave-assisted synthesis and antifungal activity of some new 1H-1,2,4-triazole derivatives
Kahveci, Bahittin; Özil, Musa; Menteşe, Emre; Bekircan, O.; Buruk, K. (Springer, 2008)A number of 3-aryl-4-arylmethylideneamino-4,5-dihydro-1H-1,2,4-triazol-5- ones were synthesized by reaction of the corresponding aromatic aldehydes with 4-amino-3-aryl-1H-1,2,4-triazol-5-ones in anhydrous ethanol under ... -
Microwave-assisted synthesis and characterization of novel metal-free and metallophthalocyanines containing four 14-membered tetraaza macrocycles
Bıyıklıoğlu, Zekeriya; Kantekin, Halit; Özil, Musa (Elsevier, 2007)The novel tetrasubstituted metal-free phthalocyanine (6) and metallophthalocyanines (7, 8) bearing four 14-membered tetraaza macrocycles moieties on peripheral positions have been synthesized by cyclotetramerization reaction ... -
Microwave-assisted synthesis of novel 2,4-dihydro-5-[4-(trifluoromethyl) phenyl]-3h-1,2,4-triazol-3-ones and potentiometric determination of their pKa in nonaqueous solvents
Özil, Musa; İslamoğlu, Fatih; Menteşe, Emre; Kahveci, Bahittin (Wiley, 2010)The novel 4-amino- or 4-aryl-substituted 2,4-dihydro-5-[(4-trifluoromethyl) phenyl]-3H-1,2,4-triazol-3-ones 3a-3g were synthesized by reaction of N-(ethoxycarbonyl)-4-(trifluoromethyl)benzenehydrazonic acid ethyl ester (2) ... -
Microwave-assisted synthesis of some 1, 2, 4-triazol-3-ones and potentiometric determination of their pKa in amfiprotic and dipolar aprotic-water mixtures
İslamoğlu, Fatih; Menteşe, Emre; Özil, Musa; Turumtay, Emine Akyüz; Kahveci, Bahittin (0-Belirlenecek, 2013)The novel 5-alkyl(aryl)-4-(aryl)-2, 4-dihydro-3H-1, 2, 4-triazol-3-ones (1-12) were synthesized by reaction of (N?-ethoxycarbonyl)-4-alkyl(aryl)hydrazonic acid ethyl ester with primary amines by microwave irradiation. ...
