Browsing by Author "Yılmaz, Fatih"
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A aonvenient synthesis of Bisbenzimidazoles from iminoester hydrochlorides Via Microwave Technique
Kahveci, Bahittin; Menteşe, Emre; Özil, Musa; Yılmaz, Fatih; Serdar, Mevlüt (Wiley-Blackwell, 2016)A simple and practical method has been developed for the synthesis of bisbenzimidazoles. Iminoester hydrochlorides of phenylacetic acids were used as intermediates in this reaction with 3,3'-diaminobenzidine under microwave ... -
Bazı yeni benzimidazol türevlerinin sentezi ve yapılarının aydınlatılması
Yılmaz, Fatih (Rize Üniversitesi / Fen Bilimleri Enstitüsü / Kimya Anabilim Dalı, 2011)Bu çalışma heterosiklik bileşikler arasında önemli bir yeri olan benzimidazol türevi bileşiklerin mikrodalga destekli senteziyle ilgilidir. Bu çalışma sonucunda 11 yeni benzimidazol türevi bileşik heterosiklik bileşikler ... -
Bazı Yeni Potansiyel Biyolojik 4-(Arylidenamino)-2, 4-dihidro-3H- 1,2,4-Triazol-3-one Bileşiklerinin Mikrodalga- destekli Sentezi ve pKa Değerlerinin Belirlenmesi
Bu çalışmada,sekiz yeni bazı potansiyel biyolojik aktif 4-(arilidenamino)-2,4-dihidro-1H-1,2,4-triazol-3-on bileşikleri mikrodalga yöntemi kullanılarak sentezlendi. Bu bileşiklerin yapıları farklı spektroskopik yöntemle ... -
Effect of microwave irradiation on the synthesis of 1,2,4-triazol-3-one derivatives and their antimicrobial activities
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Beriş, Fatih Şaban (Science Reviews 2000 Ltd, 2012)An easy efficient method for the synthesis of N-(3,5-dichlorophenyl)-5-alkyl/aryl-3H-1,2,4-triazol-3-one derivatives under microwave irradiation has been developed using the reaction of 3,5-dichloroaniline and ethoxycarb ... -
Efficient microwave-assisted synthesis of n-(2-alkyl/aryl-4-phenyl-1h-imidazol-1-yl)-2-phenylacetamides
Menteşe, Emre; Yılmaz, Fatih (Taylor & Francis Inc, 2014)An easy, efficient, and environmentally friendly method for the synthesis of N-(2-alkyl/aryl-4-phenyl-1H-imidazol-1-yl)-2-phenylacetamides from the reaction of phenyl acylbromides and phenylacetohydrazide derivatives has ... -
An efficient synthesis of some new bisbenzimidazoles via microwave technique
2,2’-[1,4 (1,3)-Phenylenedi(methylene)]bis-1 H -benzimidazole derivatives were obtained from the reaction of 1,4- or (1,3)-bisiminoester hydrochloride and o -phenylenediamine derivatives under microwave irradiation. Ester ... -
Kumarin-triazol hibrit bileşiklerinin mikrodalga destekli sentezi ve bazı biyolojik özelliklerinin incelenmesi
Yılmaz, Fatih (Recep Tayyip Erdoğan Üniversitesi / Fen Bilimleri Enstitüsü / Kimya Anabilim Dalı, 2016)Bu Çalışma, üç basamakta gerçekleştirilmiştir. İlk basamakta, 1,2,4-triazol-3-on türevlerinin sentezi için gerekli olan iminoester hidroklorürler (1a-f) ve hidrazon bileşikleri (2a-f) literatürdeki yönteme göre sentezlendi. ... -
Microwave-assisted synthesis and biological evaluation of some benzimidazole derivatives containing a 1,2,4-triazol ring
Menteşe, Emre; Karaali, Nesrin; Yılmaz, Fatih; Ülker, Serdar; Kahveci, Bahittin (Wiley-V C H Verlag Gmbh, 2013)A new series of 2-(4-(trifluoromethyl)phenyl)-1H-benzo[d]imidazole derivatives containing a 1,2,4-triazole ring were synthesized via microwave technique. This efficient procedure provides pure products within a few minutes. ... -
Microwave-Assisted Synthesis and Biological Evaluation of Some Coumarin Hydrazides
Yılmaz, Fatih; Faiz, Özlem (2018)In this work, 15 different coumarin hydrazides were successfully synthesized and screened for their antioxidant and antilipase activities. To do this, firstly, salicylaldehyde derivatives and Meldrum's Acid were reacted ... -
Microwave-assisted synthesis of some 1H-1,2,4-triazol-3-one derivatives
Karaali, Nesrin; Menteşe, Emre; Yılmaz, Fatih; Usta, Asu; Kahveci, Bahittin (Bureau Scientific Publ, 2013)4-Amino-5-(methyl/ethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one were synthesized from the reaction of (methyl/ethyl)-ester ethoxycarbonyl hydrazone with hydrazine hydrate and then, converted to corresponding Schiff bases using ... -
Microwave-assisted synthesis of some 5(6)-nitro-1h-benzimidazoles and their hydrazide derivatives
Yılmaz, Fatih; Menteşe, Emre; Karaali, Nesrin; Kahveci, Bahittin (Chem Soc Ethiopia, 2013)A series of 5(6)-nitro-1H-benzimidazole and their hydrazide derivatives were synthesized starting from iminoester hydrochloride and 4-nitro-o-phenylenediamine under microwave irradiation. the structure of all synthesized ... -
Microwave-Assisted Synthesis of Some Benzimidazole Derivatives Containing Imine Function
Akyüz, Gülay; Yılmaz, Fatih; Menteşe, Emre (2015)Benzimidazol modern ilaç keşfinde önemli bir farmakofordur. Birçok benzimidazole türevi yeni ilaç adayı bileşikler elde etmek amacıyla organik kimyacılar tarafından sentezlenmektedir. Bu çalışmada, imin fonksiyonu içeren ... -
Microwave-assisted synthesis of some new benzimidazole derivatives with their antimicrobial activity
Menteşe, Emre; Yılmaz, Fatih; Beriş, Fatih Şaban; Bekircan, Olcay; Kahveci, Bahittin (Bentham Science Publ Ltd, 2015)2-(2-Chlorobenzyl)-1H-benzimidazole (2) was prepared from the reaction of o-phenylenediamine and ethylimido-o-chlorophenylacetate hydrochloride (1) under microwave irradiation. the acetate and hydrazide derivatives of 2(2- ... -
Microwave-assisted synthesis of some new coumarin derivatives including 1,2,4-triazol-3-one and investigation of their biological activities
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Ülker, Serdar (Springer, 2015)By using the microwave technology, a new protocol has been developed for the synthesis of new coumarin derivatives including 1,2,4-triazol-3-one skeleton. This protocol proves to be efficient and environmentally friendly ... -
Microwave-assisted synthesis of some novel benzimidazole derivatives containing imine function and evaluation of their antimicrobial activity
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Özil, Musa; Karaoğlu, Şengül Alpay (Wiley, 2014)4-Bromo-o-phenylenediamine and ethylimido-p-bromophenylacetate, 1, were subjected to microwave irradiation to synthesize benzimidazole derivative, compound 2. Ester derivative, 3, and hydrazide derivative, 4, of compound ... -
Mıcrowave-assısted synthesıs of some novel benzımıdazole compounds contaınıng oxadıazole moıety
Kahveci, Bahittin; Sosan, Nesibe; Menteşe, Emre; Yılmaz, Fatih (Editura Acad Romane, 2013)5(6)-Nitro-2-alkyllaryl-1H-benzimidazoles were obtained from the reaction of iminoester hydrochlorides and 4-nitro-o-phenylenediamine, and converted to their ester and hydrazide derivatives. Hydrazide derivatives were used ... -
Mıcrowave-assısted synthesıs of some nıtro-benzımıdazoles and theır salıcyl and ısatın schıff bases
Yılmaz, Fatih; Karaali, Nesrin; Şaşmaz, Selami (Chem Soc Ethiopia, 2017)A series of 5-nitrosubstituted benzimidazole and 6-nitro substituted benzimidazole derivatives were synthesized starting from iminoester hydrochloride and 4-nitro-o-phenylenediamine under microwave irradiation. the structure ... -
A Novel route to one-pot three-component synthesis of benzimidazo [2,1-b]-quinazolin-1-one derivatives
Kahveci, Bahittin; Yılmaz, Fatih; Menteşe, Emre; Karaali, Nesrin (Bentham Science Publ Ltd, 2013)One-pot three-component synthesis of benzimidazo[2,1-b]-quinazolin-1-ones was efficiently performed under microwave irradiation and solvent-free condition. the method provides some advantages such as low cost, experimental ... -
PaCaHa inhibits proliferation of human cancer cells in vitro
Background/aim: The aim of this study was to investigate the antiproliferative and cytotoxic effects of a newly synthesized molecule named paracetamol acetohydroxamic acid (PaCaHa) on human neoplastic cell lines. Materials ... -
Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives
Menteşe, Emre; Yılmaz, Fatih; Karaali, Nesrin; Ülker, Serdar; Kahveci, Bahittin (Maik Nauka/Interperiodica/Springer, 2014)This study presents a synthesis of new series of some benzimidazole, bisbenzimidazole and perimidine derivatives via microwave technique, which, leads to the good product yields and short reaction times. the structure of ...
