Design and synthesis of some piperazine hybrid molecules

Abstract

In this work, a new series of piperazine hybrid molecules containing coumarin, isatin, salicyl, furane and 1,2,4-triazol-3-thiol moieties was synthesized in good yields. 2-[4-(4-Nitrophenyl)piperazin-1-yl] acetohydrazide was used as key intermediate to obtain these hybrid molecules. the structures of newly synthesized compounds were identified by H-1 NMR, C-13 NMR and elemental analysis data.