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Toplam kayıt 9, listelenen: 1-9
Synthesis and molecular docking study of some 5,6-dichloro-2cyclopropyl-1H-benzimidazole derivatives bearing triazole, oxadiazole, and imine functionalities as potent inhibitors of urease
(Pergamon-Elsevier Science Ltd, 2017)
A new series of benzimidazole compounds including hydrazinecarbothioamide, 1,2,4-triazole, 1,3,4-oxadiazole and imine function were synthesized starting from 5,6-dichloro-2-cyclopropyl-1H-benzimidazole. All of the benzimidazole ...
Synthesis of some new Methoxy Bridged Benzimidazolyl-Substituted phthalocyanines as potent inhibitors of urease
(Elsevier Science Sa, 2018)
In this study, the novel peripherally 4-[(2-methyl-1H-benzimidazol-1-yl)methoxy] substituted Zn(II) (3) Cu(II) (4), Co(II) (5) phthalocyanines were prepared and their structures were characterized spectro-scopically. the ...
Synthesis, antioxidant, and antibacterial activities of some new 2-(3-fluorobenzyl)-1H-benzimidazole derivatives
(Wiley, 2018)
A new series of 2-(3-fluorobenzyl)-1H-benzimidazole derivatives containing Schiff base, 1,3,4-oxadiazole, thiosemicarbazide, and 1,3,4-thiadiazole moiety was synthesized. All the synthesized compounds were investigated for ...
Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
(Academic Press Inc Elsevier Science, 2019)
A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ...
Synthesis and in vitro urease inhibition of some novel benzimidazole-based hydrazones
(Wiley, 2019)
A novel series of N '-(substituted benzylidene)-2-(5,6-dichloro-2-methyl-1H-benzimidazol-1-yl)acetohydrazides and N '-(1-(substituted phenyl)ethylidene)-2-(5,6-dichloro-2-methyl-1H-benzimidazol-1-yl)acetohydrazides were ...
Synthesis and spectroscopic characterization of novel methoxy bridged benzimidazolyl-substituted phthalocyanines as potent inhibitors of urease
(Pergamon-Elsevier Science Ltd, 2020)
In this study, novel peripherally 4-[(1H-benzimidazol-1-yl)methoxy] substituted Zn(II) (3) Cu(II) (4) and Co(II) (5) phthalocyanines were prepared and their structures were characterized spectroscopically. the light ...
Benzimidazolone-piperazine/triazole/thiadiazole/furan/thiophene conjugates: Synthesis, in vitro urease inhibition, and in silico molecular docking studies
(Wiley, 2023)
This study describes the synthesis, in vitro urease inhibition, and molecular docking studies of benzimidazolone derivatives incorporating the piperazine, triazole, thiadiazole, furan, thiophene, and thiosemicarbazide ...
Synthesis of some benzimidazole-thiophene hybrids as potential urease and lipase inhibitors
(Springer Link, 2023)
In this study, some benzimidazole-thiophene hybrid compounds containing isatin and salicyl moieties were synthesized and investigated for their urease and lipase inhibition properties. Most of the synthesized compounds ...
Synthesis and biological evaluation of coumarin-amino acid-benzotriazole conjugates
(Springer, 2024)
Objective: It is aimed to synthesize new amino acid-conjugated coumarin-benzotriazole molecules and to investigate their acetylcholinesterase, urease, and lipase inhibition properties. Methods: Urease inhibitory activities ...