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Synthesis and spectroscopic characterization of novel methoxy bridged benzimidazolyl-substituted phthalocyanines as potent inhibitors of urease

Access

info:eu-repo/semantics/closedAccess

Date

2020

Author

Akcay, Hakki Turker
Mentese, Emre
Sokmen, Bahar Bilgin

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Abstract

In this study, novel peripherally 4-[(1H-benzimidazol-1-yl)methoxy] substituted Zn(II) (3) Cu(II) (4) and Co(II) (5) phthalocyanines were prepared and their structures were characterized spectroscopically. the light absorption behaviors of the synthesized compounds (3-5) were studied by UV-Vis spectroscopy at different concentrations in different solvents. the urease inhibition activities of the synthesized compounds were also investigated. Among the synthesized molecules, compound 4 showed the best inhibitory effect against jack bean urease with IC50 values of 0.0036 +/- 0.0010 mu M. (C) 2019 Elsevier B.V. All rights reserved.

Source

Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy

Volume

228

URI

https://doi.org/10.1016/j.saa.2019.117804
https://hdl.handle.net/11436/1193

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  • PubMed İndeksli Yayınlar Koleksiyonu [1483]
  • Scopus İndeksli Yayınlar Koleksiyonu [4409]
  • WoS İndeksli Yayınlar Koleksiyonu [3797]



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