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Küçük Resim

Ratlarda Cisplatinin Oluşturduğu Karaciğer Hasarında Beyaz Çayın Etkisi 

Dizman, Fatih (Recep Tayyip Erdoğan Üniversitesi, Sağlık Bilimleri Enstitüsü, Tıbbi Biyokimya Anabilim Dalı, 2019)
Abstract: The aim of this study was to investigate the reduction or elimination of cisplatin-induced liver damage in chronic white tea-fed rats. For this purpose, 24 female Sprague Dawley rats from 3 groups of 8 were used. ...

Antioxidative and anti-inflammatory effect of thymoquinone in an acute Pseudomonas Prostatitis Rat model 

Rifaioğlu, Murat Mehmet; Nacar, Ahmet; Yüksel, Rana; Yönden, Zafer; Karcıoğlu, Murat; Zorba, Orhan Ünal; Sefil, Nebihat Kaplan (KargerKarger, 2013)
Introduction: the aim of this study is to investigate the potential antioxidant and anti-inflammatory effects of thymoquinone (TQ) to improve acute bacterial prostatitis (ABP) induced by Pseudomonas aeruginosa. Material ...

The impaired balances of oxidant/antioxidant and COX-1/COX-2 in ovarian ischemia-reperfusion injury and prevention by Nimesulide 

İsaoğlu, Ünal; Yılmaz, Mehmet; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Bilen, Habib; Yapca, Ömer Erkan; Demiryılmaz, İsmail; İsaoğlu, Neslihan; Gül, Mehmet Ali; Kumbasar, Serkan; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2012)
The aims of this study were to investigate the association of ovarian I/R injury with oxidant/antioxidant and cyclooxygenase activity and to examine the effect of nimesulide in I/R injury. Rats were divided into four groups: ...

Effect of thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat kidney 

Altuner, Durdu; Çetin, Nihal; Süleyman, Bahadır; Aslan, Zeynep; Hacımuftuoğlu, Ahmet; Gülaboğlu, Mine; İsaoğlu, Neslihan; Demiryılmaz, İsmail; Suleyman, Halis (Wolters Kluwer Medknow Publications, 2013)
Objectives: the biochemical effects of thiamine pyrophosphate on ischemia-reperfusion (IR) induced oxidative damage and DNA mutation in rat kidney tissue were investigated, and compared to thiamine. Materials and Methods: ...
Küçük Resim

Investigation and histopathological evaluation of the effects of omeprazole on the ischemia-reperfusion induced oxidative damage and DNA mutation in rat ovarian tissue 

Demiryılmaz, İsmail; Çetin, Nihal; Yapca, Ömer Erkan; Altuner, Durdu; İsaoğlu, Ünal; Özgeris, Fatma Betül; Çalık, Muhammet; Süleyman, Halis (Chemical Publishing Co., 2013)
In this study, the biochemical and histopathological effects of omeprazole on ischemia-reperfusion (I/R) induced oxidative damage in rat ovarian tissue were investigated. The moment that the animals remained motionless in ...
Küçük Resim

Effect of mirtazapine on gastric oxidative stress and DNA injury created with methotrexate in rats 

Demiryılmaz, İsmail; Uzkeser, Hülya; Çetin, Nihal; Hacımüftüoğlu, Ahmet; Bakan, Ebubekir; Altuner, Durdu (Chemical Publishing Co., 2013)
In this study, effect of mirtazapine on gastric oxidative stress and DNA injury created with methotrexate was investigated. Experimental results showed that GSH (nmol/g protein), MDA (?mol/g protein) and MPO (?/g protein) ...
Küçük Resim

Exogenous ATP administration prevents ischemia/reperfusion-induced oxidative stress and tissue injury by modulation of hypoxanthine metabolic pathway in rat ovary 

Kumbasar, Serkan; Çetin, Nihal; Yapca, Ömer Erkan; Şener, Ebru; İsaoğlu, Ünal; Yılmaz, Mehmet; Salman, Süleyman; Aksoy, Ayşe Nur; Gül, Mehmet Ali; Süleyman, Halis (Univ Federal Santa Maria, 2014)
In this study, xanthine oxidase (XO), malondialdehyde (MDA), myeloperoxidase (MPO) and glutathione (GSH) levels in the ovarian tissues of rats during the development of ischemia and postischemia-induced reperfusion were ...
Küçük Resim

Damage induced by paracetamol compared with N-acetylcysteine 

Kısaoğlu, Abdullah; Özoğul, Bünyamin; Turan, Mehmet İbrahim; Yılmaz, İsmail; Demiryılmaz, İsmail; Atamanalp, Sabri Selçuk; Bakan, Ebubekir; Süleyman, Halis (Lippincott Williams & Wilkins, 2014)
Background: This study investigated the effect of thiamine pyrophosphate (TPP) on oxidative liver damage induced in rats with high-dose paracetamol. Methods: Rats for this experiment were divided into the following groups: ...
Küçük Resim

Investigation of antiulcer and antioxidant activity of moclobemide in rats 

Albayrak, Abdulmecit; Alp, Hamit Hakan; Süleyman, Halis (Aves, 2015)
Amaç: Peptik ülser tedavisinde kullanılan çok sayıda klasik antiülser ilaç grupları bulunsa da, bu ilaçlar ile ülserin kalıcı tedavisi sağlanamamaktadır. 1950'den beri antidepresan ilaçlar non - psikiyatrik bazı hastalıkların ...
Küçük Resim

A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue 

Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Akçay, Fatih; Süleyman, Halis (Pharmaceutical Soc Korea, 2013)
In this study, the biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue were investigated. Animals were divided into four ...
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