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Küçük Resim

Protective effects of estrogen and bortezomib in kidney tissue of post-menopausal rats: an ultrastructural study 

Mercantepe, Tolga; Ünal, Deniz; Selli, Jale; Mercantepe, Filiz; Ünal, Bünyamin; Karabıyık, Tuba Nur (Taylor & Francis Ltd, 2016)
Purpose: Symptoms and disorders related to menopause and its associated estrogen deficiency have become a considerable health concern worldwide. Ovarian hormone depletion/estrogen deficiency can be usefully studied using ...
Küçük Resim

Histopathological evaluation of the effects of dexmedetomidine against pituitary damage ınduced by X-ray irradiation 

Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema (Taylor & Francis Ltd., 2022)
Background: The present study, aimed to investigate the potential negative effects of x-ray radiation and the effects of the α2-adrenergic receptor agonist dexmedetomidine on the pituitary gland. Methods: Twenty-four ...
Küçük Resim

Protective effects of tumor necrosis factor alpha inhibitors on methotrexate-induced pancreatic toxicity 

Mercantepe, Tolga; Kalkan, Yıldıray; Tümkaya, Levent; Şehitoğlu, İbrahim; Mercantepe, Filiz; Yıldırmış, Sermet (Wroclaw Medical Univ, 2018)
Background. Methotrexate (MTX), a folate antagonist, is commonly used in the treatment of many different types of cancer and inflammatory diseases, including pancreatic cancer, although its side effects on the pancreas ...
Küçük Resim

Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury 

Mercantepe, Filiz; Mercantepe, Tolga; Topçu, Atilla; Yılmaz, Adnan; Tümkaya, Levent (Springer, 2018)
Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 years has yet been discovered. This ...
Küçük Resim

Effects of gadolinium-based MRI contrast agents on liver tissue 

Mercantepe, Tolga; Tümkaya, Levent; Çeliker, Fatma Beyazal; Suzan, Zehra Topal; Çınar, Seda; Akyıldız, Kerimali; Mercantepe, Filiz; Yılmaz, Adnan (Wiley, 2018)
BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...
Küçük Resim

Effects of infliximab against methotrexate toxicity in splenic tissue via the regulation of CD3, CD68, and C200R in rats 

Mercantepe, Tolga; Tümkaya, Levent; Mercantepe, Filiz (Karger, 2018)
Methotrexate (MTX), which has been used in clinical practice for approximately 70 years, is still widely employed in the treatment of rheumatoid arthritis (RA), psoriasis, and cancer. Although MTX toxicity causes nephrotoxicity, ...
Küçük Resim

Protective effects of amifostine, curcumin and melatonin against cisplatin-induced acute kidney injury (vol 391, pg 915, 2018) 

Mercantepe, Filiz; Mercantepe, Tolga; Topçu, Atilla; Yılmaz, Adnan; Tümkaya, Levent (Springer, 2019)
.......
Küçük Resim

The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats 

Mercantepe, Tolga; Topçu, Atilla; Rakıcı, Sema; Tümkaya, Levent; Yılmaz, Adnan; Mercantepe, Filiz (Springer Heidelberg, 2019)
The purpose of this study was therefore to investigate the effects of radiotherapy on the kidney and the potential use of agents such as N-acetylcysteine (NAC) in developing a future therapeutic protocol for radiation-induced ...
Küçük Resim

An investigation of the effects of N-acetylcysteine on radiotherapy-induced testicular injury in rats 

Topçu, Atilla; Mercantepe, Filiz; Rakıcı, Sema; Tümkaya, Levent; Uydu, Hüseyin Avni; Mercantepe, Tolga (Springer, 2019)
According to data issued by the International Agency for Research on Cancer in 2012, the estimated number of new cases of all types of cancer worldwide was estimated to exceed 10 million, and 6 million of whom receive ...
Küçük Resim

Evaluation of the protective effects of amifostine and melatonin against cisplatin induced testis injury via oxidative stress and apoptosis in rats 

Eren, Hüseyin; Mercantepe, Tolga; Tümkaya, Levent; Mercantepe, Filiz; Dil, Eyüp; Horsanali, Mustafa Ozan; Yılmaz, Adnan (Academic Press Inc Elsevier Science, 2020)
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Mercantepe, Filiz (24)
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