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Küçük Resim

Ratlarda Cisplatinin Oluşturduğu Karaciğer Hasarında Beyaz Çayın Etkisi 

Dizman, Fatih (Recep Tayyip Erdoğan Üniversitesi, Sağlık Bilimleri Enstitüsü, Tıbbi Biyokimya Anabilim Dalı, 2019)
Abstract: The aim of this study was to investigate the reduction or elimination of cisplatin-induced liver damage in chronic white tea-fed rats. For this purpose, 24 female Sprague Dawley rats from 3 groups of 8 were used. ...
Küçük Resim

Investigation and histopathological evaluation of the effects of omeprazole on the ischemia-reperfusion induced oxidative damage and DNA mutation in rat ovarian tissue 

Demiryılmaz, İsmail; Çetin, Nihal; Yapca, Ömer Erkan; Altuner, Durdu; İsaoğlu, Ünal; Özgeris, Fatma Betül; Çalık, Muhammet; Süleyman, Halis (Chemical Publishing Co., 2013)
In this study, the biochemical and histopathological effects of omeprazole on ischemia-reperfusion (I/R) induced oxidative damage in rat ovarian tissue were investigated. The moment that the animals remained motionless in ...
Küçük Resim

Effect of mirtazapine on gastric oxidative stress and DNA injury created with methotrexate in rats 

Demiryılmaz, İsmail; Uzkeser, Hülya; Çetin, Nihal; Hacımüftüoğlu, Ahmet; Bakan, Ebubekir; Altuner, Durdu (Chemical Publishing Co., 2013)
In this study, effect of mirtazapine on gastric oxidative stress and DNA injury created with methotrexate was investigated. Experimental results showed that GSH (nmol/g protein), MDA (?mol/g protein) and MPO (?/g protein) ...
Küçük Resim

Exogenous ATP administration prevents ischemia/reperfusion-induced oxidative stress and tissue injury by modulation of hypoxanthine metabolic pathway in rat ovary 

Kumbasar, Serkan; Çetin, Nihal; Yapca, Ömer Erkan; Şener, Ebru; İsaoğlu, Ünal; Yılmaz, Mehmet; Salman, Süleyman; Aksoy, Ayşe Nur; Gül, Mehmet Ali; Süleyman, Halis (Univ Federal Santa Maria, 2014)
In this study, xanthine oxidase (XO), malondialdehyde (MDA), myeloperoxidase (MPO) and glutathione (GSH) levels in the ovarian tissues of rats during the development of ischemia and postischemia-induced reperfusion were ...
Küçük Resim

Damage induced by paracetamol compared with N-acetylcysteine 

Kısaoğlu, Abdullah; Özoğul, Bünyamin; Turan, Mehmet İbrahim; Yılmaz, İsmail; Demiryılmaz, İsmail; Atamanalp, Sabri Selçuk; Bakan, Ebubekir; Süleyman, Halis (Lippincott Williams & Wilkins, 2014)
Background: This study investigated the effect of thiamine pyrophosphate (TPP) on oxidative liver damage induced in rats with high-dose paracetamol. Methods: Rats for this experiment were divided into the following groups: ...
Küçük Resim

Investigation of antiulcer and antioxidant activity of moclobemide in rats 

Albayrak, Abdulmecit; Alp, Hamit Hakan; Süleyman, Halis (Aves, 2015)
Amaç: Peptik ülser tedavisinde kullanılan çok sayıda klasik antiülser ilaç grupları bulunsa da, bu ilaçlar ile ülserin kalıcı tedavisi sağlanamamaktadır. 1950'den beri antidepresan ilaçlar non - psikiyatrik bazı hastalıkların ...
Küçük Resim

A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue 

Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Akçay, Fatih; Süleyman, Halis (Pharmaceutical Soc Korea, 2013)
In this study, the biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue were investigated. Animals were divided into four ...
Küçük Resim

Effects of Hypericum perforatum and Hippophae rhamnoides extracts on indomethacin-induced gastric oxidative stress in rats 

Turan, Mehmet İbrahim; Bilen, Habib; Demiryılmaz, İsmail; Özgeriş, Fatma Betül; Baykal, Hüseyin; Türkoğlu, Murat; Süleyman, Halis (Allied Acad, 2013)
We investigate the effects of Hypericum perforatum (HP) and Hippophae rhamnoides (HR) extracts on indomethacin-induced gastric injury. Rats were divided into five groups each containing 10 animals. the first group received ...
Küçük Resim

Investigating the effect of prunus laurocerasus fruit extract in type II diabetes induced rats 

Turan, Mehmet İbrahim; Türkoğlu, Murat; Dündar, Cihat; Çelik, Nuray; Süleyman, Halis (Asian Network Scientific Information-Ansinet, 2013)
Prunus laurocerasus (PL) is the fruits of the officinalis species in the Rosaceae family. It is used as diuretic, antidiabetic, antiulcer, dermatitis and hemorrhoids. This study investigate the antidiabetic effects of PL ...
Küçük Resim

The protective effect of melatonin and agomelatin against cisplatin-induced nephrotoxicity and oxidative stress in the rat kidney 

Yılmaz, İsmayıl; Demiryılmaz, İsmail; Turan, Mehmet İbrahim; Süleyman, Bahadır; Turan, Işıl Şiltelioğlu; Altuner, Durdu; Hakan, Alp Hamit; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2013)
Cisplatin is used to treat various types of cancers. Its use is limited, however, due to nephrotoxicity, which may result from free radical damage. Evidence exists that melatonin reduces oxidative stress-induced damage. ...
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