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Küçük Resim

A comparative investigation of the nephrotoxic effects of various antihypertensive drugs in rats: biochemical and histopathological analysis 

Malkoç, İsmail; Altunkaynak, Konca; Turan, Mehmet İbrahim; Gürsan, Nesrin; Hacımüftüoğlu, Ahmet; Akçay, Fatih; Üçüncü, Yılmaz; Süleyman, Halis (Carbone Editore, 2014)
Aims: Hypertension is known to cause potentially fatal kidney damage. However, it is unclear whether long-term use of antihypertensive drugs establishes any toxic effect on the kidney. This study investigate whether ...
Küçük Resim

The protective effects of perindopril against acute kidney damage caused by septic shock 

Kostakoğlu, Uğur; Mercantepe, Tolga; Yılmaz, Hülya Kılıç; Tümkaya, Levent; Batçık, Şule; Pınarbaş, Esra; Uydu, Hüseyin Avni (Springer/Plenum Publishers, 2021)
Acute kidney injury (AKI) resulting from septic shock caused by sepsis is an important health problem encountered at rates of 55-73%. Increasing oxidative stress and inflammation following sepsis is a widely observed ...
Küçük Resim

The effect of exposure of rats during prenatal period to radiation spreading from mobile phones on renal development 

Bedir, Recep; Tümkaya, Levent; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Yılmaz, Adnan; Şahin, Osman Zikrullah (Informa Healthcare, 2015)
Background: the aim of this study was to investigate the effects of exposure to a 900-MHz electromagnetic field (EMF) produced by mobile phones on the renal development of prenatal rats. Histopathological changes and ...
Küçük Resim

The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats 

Mercantepe, Tolga; Topçu, Atilla; Rakıcı, Sema; Tümkaya, Levent; Yılmaz, Adnan; Mercantepe, Filiz (Springer Heidelberg, 2019)
The purpose of this study was therefore to investigate the effects of radiotherapy on the kidney and the potential use of agents such as N-acetylcysteine (NAC) in developing a future therapeutic protocol for radiation-induced ...
Küçük Resim

Effects of gadodiamide and gadoteric acid on rat kidneys: A comparative study 

Çeliker, Fatma Beyazal; Tümkaya, Levent; Mercantepe, Tolga; Beyazal, Mehmet; Turan, Arzu; Beyazal Polat, Hatice; Suzan, Zehra Topal; İnecikli, Mehmet Fatih; Akyıldız, Kerimali; Yılmaz, Adnan (Wiley, 2019)
Background Gadolinium-based contrast agents are complex chelates to provide contrast in NRI. However, recent studies have highlighted the deposition of free Gd+3 ion in various tissues. Purpose To evaluate the histopathological ...
Küçük Resim

The effects of dexmedetomidine on early acute kidney injury in severely burned rats 

Özdemir, Ayşe; Topçu, Atilla; Mercantepe, Tolga; Arpa, Medeni; Karakaş, Sibel Mataracı; Özdemir, Ali Sezin; Tümkaya, Levent; Mercantepe, Filiz (Verduci Publisher, 2023)
OBJECTIVE: Burns are a global medical and economic problem. In addition to high costs, the lengthy therapeutic process and the emotional trauma experienced by patients and their families indirectly worsen the socioeconomic ...
Küçük Resim

Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis 

Dil, Eyüp; Topçu, Atilla; Mercantepe, Tolga; Tümkaya, Levent; Akyıldız, Kerimali; Saral, Sinan; Yılmaz, Adnan (Springer, 2023)
Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ...

Investigation of the effects of fosfomycin in kidney damage caused by CLP-induced sepsis 

Yıldız, İlknur Esen; Mercantepe, Tolga; Bahçeci, İlkay; Arpa, Medeni; Batçık, Şule; Yıldız, Yasin; Tümkaya, Levent (MDPI, 2025)
Sepsis, a life-threatening condition characterized by dysregulated host responses to infection, often leads to multi-organ dysfunction, including kidney injury. Kidney damage in sepsis can have severe consequences and is ...



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YazarTümkaya, Levent (7)Mercantepe, Tolga (6)Yılmaz, Adnan (4)Topçu, Atilla (3)Akyıldız, Kerimali (2)Arpa, Medeni (2)Batçık, Şule (2)Mercantepe, Filiz (2)Akçay, Fatih (1)Altunkaynak, Konca (1)... Daha FazlaAnahtar Kelime
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Oxidative stress (4)Inflammation (3)Sepsis (2)Agomelatine (1)Antihypertensive agents (1)Apoptosis (1)Burn (1)Caspase-3 (1)... Daha FazlaYayın Tarihi2020 - 2025 (4)2014 - 2019 (4)Mevcut Dosya(lar)Tam Metni Olanlar (8)

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