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Toplam kayıt 13, listelenen: 1-10
Synthesis and antimicrobial activities of some new 1,2,4-triazole derivatives
(MDPI, 2010)
Some novel 4,5-disubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one (3, 6, 8, 9) derivatives and or 3-(4-methylphenyl)[1,2,4]triazolo[3,4-b][1,3]benzoxazole (5) were synthesized from the reaction of various ester ethoxycarbo ...
Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2013)
Norfloxacin was converted to 7-(4-amino-2-fluorophenyl)piperazin derivative (2) via the formation of nitro compound. the synthesis of the norfloxacin derivatives containing 1,3-thiazole or 1,3-thiazolidin moiety was performed ...
Synthesis and antimicrobial activity of new piperazine-based heterocyclic compounds
(Walter de Gruyter Gmbh, 2017)
The hydrazide 5, that was obtained from -1-(4-fluorophenyl) piperazine (1), was converted to the cor-responding carbothioamides 6a-c by the reaction with alkyl(aryl) isothiocyanates. the synthesis of conazole analogs 10a-f ...
Synthesis and antimicrobial activity evaluation of new norfloxacine-azole hybrids
(Walter de Gruyter Gmbh, 2018)
Norfloxacin-azole hybrids 3 and 6a,b were synthesized starting from norfloxacin. the treatment of these compounds with amines as a one-pot three-component reaction produced the corresponding amino derivatives 4a,b, 7a-g ...
Structure-based hybridization, microwave prompted synthesis and biological evaluation of novel 4-(2-fluoro-4-nitrophenyl)morpholine derivatives
(Bentham Science Publ Ltd, 2018)
1,3,4-oxadiazole-2-thiole 6 was obtained from 4-(2-fluoro-4-nitrophenyl)morpholine (2) by the reduction of its nitro group and the sequential treatment of the resulting amine with ethyl bro-moacetate, hydrazine hydrate, ...
Synthesis and antimicrobial activities of some new biheterocyclic compounds containing 1, 2, 4-triazol-3-one and 1, 3, 4-thiadiazole moieties
(TÜBİTAK, 2010)
2-(4-Amino-3-(4-chlorophenyl)-5-oxo-4, 5-dihydro-1 H-1, 2, 4-triazol-1-yl)-N'-[(2, 6 dihalogenophenyl)-methylene]acetohydrazides (3a, b) was obtained via the formation of 2-(4-amino-3-(4-chlorophenyl)-5-oxo-4, 5-dihydro-1 ...
Synthesis of some new biheterocyclic triazole derivatives and evaluation of their antimicrobial activity
(TÜBİTAK, 2010)
2-{3-(4-Substitutedbenzyl)-4-[2-(1H-indol-3-yl)ethyl]-5-oxo-4, 5-dihydro-1H-1,2,4-triazol-1-yl}-N' -(arylmethylene) acetohydrazides (5a-g), 4-amino-2-{3-(4-substitutedbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1- yl}-N' ...
Synthesis and antimicrobial activities of some new 1,2,4-triazole derivatives
(TUBİTAK, 2010)
The synthesis of ethyl [3-(cyanomethyl)-5-alkyl-4H-1,2,4-triazol-4-yl] carbamates (2a-d) was performed starting from ethyl 2-[ethoxy(4-(aryl)methylene] hydrazinecarboxylates (1a, 1b). The treatment of 2a with thiosemicarbazide ...
Synthesis and biological activity studies of new hybrid molecules containing tryptamine moiety
(Springer, 2012)
The synthesis of N?-(4-substitutedphenylsulfonyl)-2-{4-[2-(1H-indol- yl)ethyl]-3-(4-chlorobenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl} acetohydrazides (3a-c), 2-{4-[2-(1H-indol-3-yl)ethyl]-3-(4-chlorobenzyl)-5-oxo- ...
Design and synthesis of new 1,2,4-triazole deriaties containing morpholine moiety as antimicrobial agents
(TÜBİTAK, 2012)
2-Morpholine-4ylethyl-3H -1,2,4-triazole-3-ones (2a, 2b) were obtained from the condensation between the corresponding ethoxycarbonylhydrazones and 2-morpholinoethanamine. 2a was conerted to acetohydrazide (4) ia the ...