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dc.contributor.authorGürkan, Çağla Gül
dc.contributor.authorKeleş, Gonca Çayır
dc.contributor.authorKurt, Sevda
dc.contributor.authorÇiftçi, Alper
dc.contributor.authorAyas, Bülent
dc.contributor.authorGüler, Şevki
dc.contributor.authorÇetinkaya, Burcu Özkan
dc.date.accessioned2020-12-19T19:35:55Z
dc.date.available2020-12-19T19:35:55Z
dc.date.issued2019
dc.identifier.citationGürkan, Ç. G., Keleș, G. Ç., Kurt, S., Çiftçi, A., Ayas, B., Güler, Ş., & Çetinkaya, B. Ö. (2019). Histopathological and biochemical evaluation of paeoniflorin administration in an experimental periodontitis model. Journal of oral science, 61(4), 554–557. https://doi.org/10.2334/josnusd.18-0427en_US
dc.identifier.issn1343-4934
dc.identifier.issn1880-4926
dc.identifier.urihttps://doi.org/10.2334/josnusd.18-0427
dc.identifier.urihttps://hdl.handle.net/11436/1370
dc.descriptionKURT, Sevda/0000-0002-3711-6520en_US
dc.descriptionWOS: 000509391800015en_US
dc.descriptionPubMed: 31588098en_US
dc.description.abstractThe purpose of this study was to evaluate the effects of administered Paeoniflorin (Pae) on periodontal tissues within an experimental periodontitis model. Forty male Wistar rats were used in this study and experimental periodontitis was created in all rats except in the control group (n = 10, first group). in the periodontitis group, experimental periodontitis was created but no other application was performed (n = 10, second group). in the other groups created experimental periodontitis, systemic Pae (n = 10, third group) or saline (n = 10, fourth group) was applied. A biochemical analysis of the gingival vascular endothelial growth factor (VEGF) levels and a histomorphometric analysis (measurements of the area of alveolar bone, alveolar bone resorption, and attachment loss) were performed. in the Pae group, the area of the alveolar bone was increased, while alveolar bone resorption and attachment loss decreased. Gingival VEGF levels increased in all groups that created experimental periodontitis and the greatest increase seen in the Pae group. Histomorphometric and biochemical analyses in this study suggest that Pae has a curative effect on periodontal tissues. However, additional studies are needed to confirm these results.en_US
dc.description.sponsorshipScientific Research Fund of Ondokuz Mayis University in Samsun/TurkeyOndokuz Mayis University [PYO.DIS.1904.15.001]en_US
dc.description.sponsorshipThis study was supported by the Scientific Research Fund of Ondokuz Mayis University in Samsun/Turkey (Project number: PYO.DIS.1904.15.001).en_US
dc.language.isoengen_US
dc.publisherNihon Univ, School Dentistryen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExperimental periodontitisen_US
dc.subjectHistologyen_US
dc.subjectHerbal medicineen_US
dc.titleHistopathological and biochemical evaluation of paeoniflorin administration in an experimental periodontitis modelen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Diş Hekimliği Fakültesi, Klinik Bilimler Bölümüen_US
dc.contributor.institutionauthorKurt, Sevda
dc.identifier.doi10.2334/josnusd.18-0427
dc.identifier.volume61en_US
dc.identifier.issue4en_US
dc.identifier.startpage554en_US
dc.identifier.endpage557en_US
dc.ri.editoaen_US
dc.relation.journalJournal of Oral Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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