| dc.contributor.author | Boran, Halis | |
| dc.contributor.author | Terzi, Serap | |
| dc.date.accessioned | 2020-12-19T19:48:23Z | |
| dc.date.available | 2020-12-19T19:48:23Z | |
| dc.date.issued | 2017 | |
| dc.identifier.citation | Boran, H., & Terzi, S. (2017). Stress-Induced Transcriptional Changes and DNA Damage Associated with Bis(2-ethylhexyl) Adipate Exposure in Zebrafish (Danio rerio) Larvae. Bulletin of environmental contamination and toxicology, 99(3), 308–314. https://doi.org/10.1007/s00128-017-2116-4 | en_US |
| dc.identifier.issn | 0007-4861 | |
| dc.identifier.issn | 1432-0800 | |
| dc.identifier.uri | https://doi.org/10.1007/s00128-017-2116-4 | |
| dc.identifier.uri | https://hdl.handle.net/11436/2063 | |
| dc.description | WOS: 000408269400004 | en_US |
| dc.description | PubMed: 28536799 | en_US |
| dc.description.abstract | The present study evaluates potential toxic effects of bis(2-ethylhexyl) adipate (DEHA) plasticizer to larval (72 h post fertilization) zebrafish (Danio rerio) by analyzing changes in expression levels of stress-related genes (p53, rad51 and xrcc5) and assessing possible DNA damage of DEHA in larvae. the lethal concentration for 50% mortality (LC50) in larval zebrafish exposed for 96 h to 0-200 mg L-1 DEHA was 89.9 +/- 8.03 mg L-1. A concentration-dependent increase in DNA strand breaks was detected in cells from larvae exposed for 96 h to DEHA. There were some significant differences in induction of stress-related genes in larvae exposed to DEHA relative to control. | en_US |
| dc.description.sponsorship | Recep Tayyip Erdogan UniversityRecep Tayyip Erdogan University [2015.53001.103.01.02] | en_US |
| dc.description.sponsorship | This project was funded by Recep Tayyip Erdogan University, Scientific Research Projects Fund (Project No. 2015.53001.103.01.02). the information contained in this article was extracted from a master's thesis by the author, Serap Terzi. | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Springer | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Bis(2-ethylhexyl) adipate | en_US |
| dc.subject | Gene expression | en_US |
| dc.subject | Genotoxicity | en_US |
| dc.subject | Acute toxicity | en_US |
| dc.subject | Zebrafish | en_US |
| dc.title | Stress-induced transcriptional changes and DNA damage associated with bis(2-ethylhexyl) adipate exposure in Zebrafish (Danio rerio) larvae | en_US |
| dc.type | article | en_US |
| dc.contributor.department | RTEÜ, Su Ürünleri Fakültesi, Su Ürünleri Temel Bilimler Bölümü | en_US |
| dc.contributor.institutionauthor | Boran, Halis | |
| dc.contributor.institutionauthor | Terzi, Serap | |
| dc.identifier.doi | 10.1007/s00128-017-2116-4 | |
| dc.identifier.volume | 99 | en_US |
| dc.identifier.issue | 3 | en_US |
| dc.identifier.startpage | 308 | en_US |
| dc.identifier.endpage | 314 | en_US |
| dc.relation.journal | Bulletin of Environmental Contamination and Toxicology | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
