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dc.contributor.authorOral, Akgün
dc.contributor.authorHalıcı, Zekai
dc.contributor.authorBayır, Yasin
dc.contributor.authorTopçu, Atilla
dc.contributor.authorUn, Harun
dc.contributor.authorBilgin, Aslı Özbek
dc.contributor.authorAtmaca, Hasan Tarık
dc.date.accessioned2020-12-19T19:48:26Z
dc.date.available2020-12-19T19:48:26Z
dc.date.issued2017
dc.identifier.citationOral, A., Halici, Z., Bayir, Y., Topcu, A., Un, H., Bilgin, A. O., & Atmaca, H. T. (2017). Effects of oral zinc administration on long-term ipsilateral and contralateral testes damage after experimental testis ischaemia-reperfusion. Andrologia, 49(6), 10.1111/and.12673. https://doi.org/10.1111/and.12673en_US
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.urihttps://doi.org/10.1111/and.12673
dc.identifier.urihttps://hdl.handle.net/11436/2078
dc.descriptionOral, Akgun/0000-0002-5250-7335; bayir, yasin/0000-0003-3562-6727; Ozbek bilgin, Asli/0000-0001-9027-4299; UN, Harun/0000-0003-1772-282X; ATMACA, HASAN TARIK/0000-0001-8379-4114en_US
dc.descriptionWOS: 000408624600008en_US
dc.descriptionPubMed: 27681996en_US
dc.description.abstractThe purpose of this study was to examine potential long-term post-torsion changes that can occur in the histopathology, biochemistry and spermatogenesis of both torsioned and nontorsioned opposite testes. the study also determines the effect of zinc (Zn) administration on the testicular torsion/detorsion (T/D) damage on both testes. Forty-eight male rats, divided equally into eight groups: (SHAM), (SHAM+,Zn+), (T/D+, Zn- 1 month), (T/D+, Zn- 2 months), (T/D+, Zn- 3 months), (T/D+, Zn+ 1 months), (T/D+, Zn+ 2 months), (T/D+, Zn+ 3 months), have been used. Drug administration was carried out by adding 100 mu g (0.016 ml/rat) Zn per rat to drinking water in related groups. Testicular damage decreased superoxide dismutase (SOD) and glutathione (GSH) and increased malondialdehyde (MDA) in the testis tissues of rats, while Zn administration increased SOD and GSH and decreased MDA in the testis tissues in comparison with the SHAM group. the beneficial effect of zinc sulphate was more evident on the nonrotated testis than the rotated testis. in the histopathological study, a significant decrease in torsion and detorsion injuries was observed in the treatment groups compared to the torsion and detorsion groups. We found a protective effect of zinc sulphate on oxidative stress as a result of T/D injuries in rats, especially for the nonrotated testis; results were supported histopathologically.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntioxidanten_US
dc.subjectRaten_US
dc.subjectTestisen_US
dc.subjectTorsionen_US
dc.subjectZincen_US
dc.titleEffects of oral zinc administration on long-term ipsilateral and contralateral testes damage after experimental testis ischaemia-reperfusionen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.contributor.institutionauthorTopçu, Atilla
dc.identifier.doi10.1111/and.12673
dc.identifier.volume49en_US
dc.identifier.issue6en_US
dc.relation.journalAndrologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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