Relationship between 18F-FDG uptake on PET/CT and expression of Ki-67 and p53 proteins in patient with lung cancer: a clinocopathologic study

Abstract

Introduction Lung cancer is the 2nd most common malignancy in both of men and women. It is also the most common cause of cancer related deaths.1 Nearly 85% of lung cancers were diagnosed as large cell carcinoma, adenocarcinoma (AC), and squamous cell carcinoma (SCC) classified as non-small cell lung carcinoma (NSCLC). One third of the newly diagnosed NSLC patients were diagnosed at advanced stages (Stage IIIA or IIIB), and they are not suitable for surgical treatment. The 5-year survival rate of these patients is 16%.2,3