Microwave-assisted synthesis of some new benzylidenamino compounds and potentiometric determination of their pKa

Abstract

A growing body of literature has shown the effectiveness of using microwaves in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new benzylidenamino compounds (4a-f) via microwave heating using a monomode microwave. Compounds 4a-f were potentiometrically titrated with tetrabutylammonium hydroxide (TBAH) in four nonaqueous solvents (isopropyl alcohol, ferf-butyl alcohol, acetonitrile and N,N-dimethyl formamide). Also half-neutralization potential values and the corresponding pKa values were determined in all cases.