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dc.contributor.authorYılmaz, Fatih
dc.contributor.authorFaiz, Özlem
dc.date.accessioned2020-12-19T20:41:49Z
dc.date.available2020-12-19T20:41:49Z
dc.date.issued2018
dc.identifier.issn2149-0120
dc.identifier.issn2149-0120
dc.identifier.urihttps://doi.org/10.18596/jotcsa.390928
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpJMU1ERXlNZz09
dc.identifier.urihttps://hdl.handle.net/11436/5585
dc.description.abstractIn this work, 15 different coumarin hydrazides were successfully synthesized and screened for their antioxidant and antilipase activities. To do this, firstly, salicylaldehyde derivatives and Meldrum's Acid were reacted in absolute ethanol with catalytic amount of pyridine to obtain coumarin-3-carboxylic acid derivatives (1a-e). Then, these compounds were treated with 1H-benzotriazole in dichloromethane by using thionyl chloride to synthesize benzotriazole derivatives (2a-e). Then, compounds 2a-e were reacted with three commercial hydrazides (nicotinic hydrazide, benzhydrazide,and phenyl acetichydrazide) in ethanol by using microwave irradiation and conventional heating procedures to obtain final products (3-5a-e). Finally, these compounds were tested for their anti-oxidant and anti-lipase activities. The structure of newly synthesized compounds was identified by IR, 1H NMR, 13C NMR, and elemental analysis data.en_US
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectKimya, Analitiken_US
dc.subjectKimya, Uygulamalıen_US
dc.subjectKimya, İnorganik ve Nükleeren_US
dc.subjectKimya, Tıbbien_US
dc.subjectKimya, Organiken_US
dc.subjectFizikokimyaen_US
dc.subjectSpektroskopien_US
dc.subjectTermodinamiken_US
dc.titleMicrowave-Assisted Synthesis and Biological Evaluation of Some Coumarin Hydrazidesen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜen_US
dc.identifier.doi10.18596/jotcsa.390928
dc.identifier.volume5en_US
dc.identifier.issue2en_US
dc.identifier.startpage551en_US
dc.identifier.endpage568en_US
dc.ri.editoaen_US
dc.relation.journalJournal of the Turkish Chemical Society, Section A: Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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