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dc.contributor.authorKalaycıoğlu, Ezgi
dc.contributor.authorÇetin, Mustafa
dc.contributor.authorKiriş, Tuncay
dc.contributor.authorÖzyıldız, Ali Gökhan
dc.contributor.authorTuran, Turhan
dc.contributor.authorYılmaz, Ahmet Seyda
dc.date.accessioned2022-10-05T05:31:56Z
dc.date.available2022-10-05T05:31:56Z
dc.date.issued2021en_US
dc.identifier.citationKalaycıoğlu, E., Çetin, M., Kırış, T., Özyıldız, A. G., Turan, T., & Yılmaz, A. S. (2021). FEV1 is independently related with impaired left atrial strain in chronic obstructive pulmonary disease patients: A speckle tracking study. The clinical respiratory journal, 15(12), 1359–1367. https://doi.org/10.1111/crj.13442en_US
dc.identifier.issn1752-6981
dc.identifier.issn1752-699X
dc.identifier.urihttps://doi.org/10.1111/crj.13442
dc.identifier.urihttps://hdl.handle.net/11436/6650
dc.description.abstractBackground Atrial fibrillation (AF) is common in chronic obstructive pulmonary disease (COPD) patients. It is known that impaired forced expiratory volume in 1 s (FEV1) is one of the risk factors of cardiovascular disease. Two-dimensional speckle tracking echocardiography (2D-STE) can detect deterioration of left atrial mechanical functions in the subclinical stage. We hypothesized that reduced lung functions, measured by FEV1 in COPD patients, may be associated with impaired left atrial (LA) mechanical functions. Objectives Present study included 127 consecutive COPD patients. We divided study population into two groups: patients with normal LA strain (n = 20) or with impaired LA strain (n = 107). Results In univariate logistic regression analysis, age (p: 0.001), FEV1% (p < 0.001), FEV1 (p < 0.001), FEV1/forced vital capacity (FVC) (p: 0.014), white blood cell (p: 0.012), LA Max vol (p: 0.026), C-reactive protein (p :0.001), arterial oxygen pressure (PaO2) (p: 0.019), arterial oxygen saturation (SO2) (p: 0.021), left ventricle ejection fraction (LVEF) (p: 0.042), and mitral A-wave velocity (p: 0.017) were associated with impaired LA-strain. In multivariate logistic regression analysis, age (p: 0.043), FEV1 (p < 0.001), LA Max vol (p: 0.004), and LVEF (p: 0.004) were independently associated with impaired LA strain. Conclusion FEV1 is associated with impaired left atrial strain independently of arterial blood gas and left ventricular diastolic dysfunction parameters in COPD patients with preserved left ventricular systolic function.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic obstructive pulmonary diseaseen_US
dc.subjectForced expiratory volumeen_US
dc.subjectLeft atrial mechanical functionen_US
dc.subjectTwo-dimensional speckle tracking echocardiographyen_US
dc.titleFEV1 is independently related with impaired left atrial strain in chronic obstructive pulmonary disease patients: A speckle tracking studyen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.contributor.institutionauthorÇetin, Mustafa
dc.contributor.institutionauthorÖzyıldız, Ali Gökhan
dc.contributor.institutionauthorYılmaz, Ahmet Seyda
dc.identifier.doi10.1111/crj.13442en_US
dc.identifier.volume15en_US
dc.identifier.issue12en_US
dc.identifier.startpage1359en_US
dc.identifier.endpage1367en_US
dc.relation.journalThe Clinical Respiratory Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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