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dc.contributor.authorSerbest, Kerim
dc.contributor.authorDural, Bayram
dc.contributor.authorÇöl Ayaz, Melek
dc.contributor.authorZengin, Ali
dc.contributor.authorEmirik, Mustafa
dc.date.accessioned2022-12-09T11:45:32Z
dc.date.available2022-12-09T11:45:32Z
dc.date.issued2021en_US
dc.identifier.citationSerbest, K., Dural, B., Çol Ayvaz, M., Zengin, A. & Emirik, M. (2021). Iron(III) Complexes Derived From Azo-Containing Salicylaldoxime Ligands: Synthesis, Structures and Biological Evaluations. El-Cezeri, 8(3), 1184-1201. https://doi.org/10.31202/ecjse.905307en_US
dc.identifier.issn2148-3736
dc.identifier.urihttps://doi.org/10.31202/ecjse.905307
dc.identifier.urihttps://hdl.handle.net/11436/7255
dc.description.abstractTwo novel mononuclear Fe(III) complexes derived from azo-containing salicylaldoxime ligands were synthesized and characterized by elemental analyses, spectroscopic data i.e. IR, 1H NMR, UV-Vis, electrospray ionization mass spectra, molar conductivity, and magnetic susceptibility measurements. Both the experimental and theoretical results strongly suggest that the ligands have a major contribution to the azo enol imine form instead of the hydrazo keto imine and azo keto amine forms in solution/solid-state. The electronic spectra of the ligands and their iron(III) complexes were calculated theoretically for the band assignments by using DFT and TD-DFT/CPCM methods. DNA binding, cleavage, and antioxidative activities of the investigated compounds were studied. It has been shown that the ligands and their iron (III) complexes tested bind to DNA via the intercalative mode. It was observed that all molecules tested inhibited topoisomerase I almost to the same degree. One of the most striking results among the antioxidant activity tests is that the hydroxyl radical scavenging activities of the ligands and complexes are higher than the standard antioxidant mannitol.en_US
dc.language.isoengen_US
dc.publisherTUBİTAK Scientific & Technical Research Council Turkeyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntioxidant activityen_US
dc.subjectAzo-oximeen_US
dc.subjectDFTen_US
dc.subjectDNA interactionen_US
dc.subjectIron(III) complexen_US
dc.titleIron(III) complexes derived from azo-containing salicylaldoxime ligands: Synthesis, structures and biological evaluationsen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Fen - Edebiyat Fakültesi, Kimya Bölümüen_US
dc.contributor.institutionauthorSerbest, Kerim
dc.contributor.institutionauthorDural, Bayram
dc.contributor.institutionauthorZengin, Ali
dc.contributor.institutionauthorEmirik, Mustafa
dc.identifier.doi10.31202/ecjse.905307en_US
dc.identifier.volume8en_US
dc.identifier.issue3en_US
dc.identifier.startpage1184en_US
dc.identifier.endpage1201en_US
dc.relation.journalEl-Cezeri Journal of Science and Engineeringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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