Ara
Toplam kayıt 90, listelenen: 31-40
Conventional and microwave-assisted synthesis of novel 1,2,4-triazole derivatives containing tryptamine skeleton and evaluation of antimicrobial activity
(Bentham Science Publishing, 2021)
1,2,4-Triazole-3-one (3) obtained from tryptamine was transformed to the corresponding carbox(thio)amides via several steps (6a-d). Their reaction with sodium hydroxide performed the 1,2,4triazole derivatives (7a-d). ...
Microwave-assisted synthesis of novel mannich base and conazole derivatives containing biologically active pharmacological groups
(Bentham Science Publishers, 2021)
Background: The aim of this study was to synthesize new Mannich bases and conazol derivatives with biological activity by the microwave-assisted method. Introduction: 1,2,4-Triazole-3-one (3) acquired from tryptamine was ...
Elucidation of Bioactive compounds in flower extracts of Camellia sinensis by HPLC-DAD-MS/MS and their inhibitory effects on replicative bacterial DNA polymerases
(Elsevier, 2022)
Camellia sinensis L. (C. sinensis) is an economically valuable crop whose leaves are used to produce tea. Tea flowers extracts (TFE) have been tested for their DNA polymerase inhibitory effect experimentally and in silico. ...
Conventional and microwave irradiated synthesis, biological activity evaluation of highly substituted indole-triazole hybrids
(Elsevier, 2022)
In the present study, a series of new indole-3-carbaldehyde embedded triazole derivatives have been synthesized. 4-{[(1E)-1H-indol-3-ylmethylidene]amino}-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (2) were converted to ...
The therapeutic potency of hesperis matronalis subsp. matronalis for alzheimer's and microbial diseases
(Süleyman Demirel University, 2021)
The goal of the present study, to investigate for the methanolic extract from the aerial parts of Hesperis
matronalis subsp. matronalis in terms of acetylcholinesterase (AChE) and butyrylcholinesterase
inhibitory and ...
Synthesis and antimicrobial activity of new piperazine-based heterocyclic compounds
(Walter de Gruyter Gmbh, 2017)
The hydrazide 5, that was obtained from -1-(4-fluorophenyl) piperazine (1), was converted to the cor-responding carbothioamides 6a-c by the reaction with alkyl(aryl) isothiocyanates. the synthesis of conazole analogs 10a-f ...
Investigating the antioxidant and antimicrobial activities of different vinegars
(Springer, 2017)
In this study, the antioxidant contents and the antimicrobial activities of 18 vinegar samples were investigated. For this purpose, total flavonoid contents (TFC) and total phenolic contents (TPC) of different vinegar ...
New pyridine derivatives as antiurease inhibitors: Synthesis and their evaluation for antimicrobial activities
(Editura Acad Romane, 2017)
6-Morpholin-4-ylpyridin-3-amine (3) gathered starting from morpholine by two steps was converted into the corresponding arylidenehydrazides through the reaction with several aromatic aldehydes. the treatment of compound 3 ...
In vitro biological activity of some new 1,2,4-triazole derivatives with their potentiometric titrations
(Natl Inst Science Communication & Information Resources-Niscair, 2017)
In this study, 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones 3 have been reacted with 4-methoxy-3-(p-toluenesulfonyloxy)-benzaldehyde 1 to afford the corresponding nine new 3-alkykary1)-4-[4-methoxy-3-(p-tolu ...
Structure-based hybridization, conventional and microwave irradiated synthesis, biological evaluation and molecular docking studies of new compounds derived from thiomorpholin
(Bentham Science Publ Ltd, 2017)
Background: the amine 2 obtained via two steps starting from thiomorpholine was converted into the corresponding 1,3-thiazole (4), arylmethileneamino (5a- d) and hydrazide (7) derivatives using conventional and also microwave ...