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Toplam kayıt 34, listelenen: 31-34
Evaluation of the therapeutic effects of arbutin on cisplatin-induced ovarian toxicity in rats through endoplasmic reticulum stress and Nrf2 pathway
(Elsevier, 2023)
Arbutin (ARB) is a glycosylated hydroquinone with potent antioxidant effects. Although cisplatin (CP) is widely
used in chemotherapy, its toxicity in healthy tissues, including ovotoxicity, is an insurmountable problem. ...
The association of Sort1 expression with LDL subfraction and inflammation in patients with coronary artery disease
(Taylor & Francis Ltd., 2023)
Background: Controversial effect of sortilin on lipoprotein metabolism in the development of atherosclerosis reveals the need for more extensive research Objectives: The aim of this study was to investigate the association ...
Gallic acid attenuates torsion/detorsion-induced testicular injury in rats through suppressing of HMGB1/NF- κB axis and endoplasmic reticulum stress
(Elsevier, 2024)
It was aimed to evaluate whether gallic acid (GA) have a beneficial effect in the testicular ischemia/reperfusion injury (IRI) model in rats for the first time. Testicular malondialdehyde, 8-hydroxy-2 '-deoxyguanosine, ...
Arbutin abrogates cisplatin-induced hepatotoxicity via upregulating Nrf2/HO-1 and suppressing genotoxicity, NF-κB/iNOS/TNF-α and caspase-3/Bax/Bcl2 signaling pathways in rats
(Oxford University Press, 2024)
Background: Cisplatin is a potent anticancer agent widely employed in chemotherapy. However, cisplatin leads to toxicity on non-targeted healthy organs, including the liver. We investigated the hepatoprotective mechanism ...