Yazar "RTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü" için Scopus İndeksli Yayınlar Koleksiyonu listeleme
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Beta-lactamase genes in carbapenem resistance Acinetobacter baumannii isolates from a Turkish university hospital
Coşkun, Umut Safiye Say; Çalışkan, Emel; Çiçek, Ayşegül Çopur; Turumtay, Halbay; Sandallı, Cemal (J Infection Developing Countries, 2019)Introduction: the spread of Acinetobacter baumannii, resistant to most of the available antimicrobial agents, is a serious health problem. the high rate of carbapenem resistance among Acinetobacter baumannii isolates is ... -
Biochemical and pathological changes in the male rat kidney and bladder following exposure to continuous 900-MHz electromagnetic field on postnatal days 22-59
Türedi, Sibel; Kerimoğlu, Gökçen; Mercantepe, Tolga; Odacı, Ersan (Taylor & Francis Ltd, 2017)Purpose: To investigate the effect on male rat kidney and bladder tissues of exposure to 900-megahertz (MHz) electromagnetic field (EMF) applied on postnatal days 22-59, inclusive. Materials and methods: Twenty-four male ... -
Can dexmedetomidine be effective in the protection of radiotherapy-induced brain damage in the rat?
Çınar, Seda; Tümkaya, Levent; Mercantepe, Tolga; Saral, Sinan; Rakıcı, Sema; Yılmaz, Adnan; Topçu, Atilla; Şen, Ahmet; Karakaş, Sibel (Springer, 2021)Approximately 7 million people are reported to be undergoing radiotherapy (RT) at any one time in the world. However, it is still not possible to prevent damage to secondary organs that are off-target. This study, therefore, ... -
Can prenatal exposure to a 900 MHz electromagnetic field affect the morphology of the spleen and thymus, and alter biomarkers of oxidative damage in 21-day-old male rats?
Hancı, Hatice; Türedi, Sibel; Topal, Zehra Suzan; Mercantepe, Tolga; Bozkurt, İlyas; Kaya, Haydar; Ersöz, Şafak; Ünal, Bünyamin; Odacı, Ersan (Taylor & Francis Ltd, 2015)We investigated the effects of a 900 Megahertz (MHz) electromagnetic field (EMF), applied during the prenatal period, on the spleen and thymus of 21-day-old male rat pups. Pregnant Sprague-Dawley rats were divided into ... -
Carbonic anhydrase I and II autoantibodies in Behcet's disease
Mentese, Ahmet; Alver, Ahmet; Demir, Selim; Sümer, Ayşegül; Özer Yaman, Serap; Karkucak, Murat; Aydın Çapkın, Arzu; Us Altay, Diler; Turan, İbrahim (Publisaude-Edicoes Medicas Lda, 2017)Background: Behcet's disease ( BD) is a vasculitis, seen more frequently around the Mediterranean and the Far East, and evinces with oral and genital ulcerations, skin lesions and uveitis. Carbonic anhydrase ( CA) is a ... -
Carriage of class 1 and 2 integrons in acinetobacter baumannii and pseudomonas aeruginosa isolated from clinical specimens and a novel gene cassette array: bla(OXA-11)-cmlA7
Mengeloğlu, Fırat Zafer; Çiçek, Ayşegül Çopur; Koçoğlu, Esra; Sandallı, Cemal; Budak, Emine Esra; Özgümüş, Osman Birol (Ankara Microbiology Soc, 2014)The dissemination of antibiotic resistance genes between bacteria leads to serious problems in the treatment of infectious diseases. It has been shown that resistance genes can also be carried by the integrons. There are ... -
Changes in testicular morphology and oxidative stress biomarkers in 60-day-old Sprague Dawley rats following exposure to continuous 900-MHz electromagnetic field for 1 h a day throughout adolescence
Hancı, Hatice; Kerimoğlu, Gökçen; Mercantepe, Tolga; Odacı, Ersan (Pergamon-Elsevier Science Ltd, 2018)The purpose of this study was to investigate the 60-day-old male rat testis following exposure to continuous 900-megahertz (MHz) electromagnetic field (EMF) throughout the adolescent period using histopathological and ... -
Characterization of class 1 and class 2 integron gene cassettes in escherichia coil strains isolated from urine cultures: A multicenter study
Çopur Çiçek, Ayşegül; Sandallı, Cemal; Budak, Emine Esra; Yağmur, Gülhan; Çizmeci, Zeynep; Ak, Sibel; Balcı, Pervin Özlem; Say Coşkun, Safiye Umut; Ay Altıntop, Yasemin; Fırat, Mehmet; Sarı, Fatma; Çalışkan, Ahmet; Yıldız, Nazan; Sancaktar, Metin; Özgümüş, Osman Birol (Ankara Microbiology Soc, 2016)Escherichia coli is the most common pathogen isolated from both nosocomial and community acquired urinary tract infections. Although there are many studies from different centers concerning the antibiotic susceptibility ... -
Characterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing beta-lactamases in Pseudomonas aeruginosa in Turkey
Iraz, Meryem; Düzgün, Azer Özad; Çiçek, Ayşegül Çopur; Bonnin, Remy A.; Ceylan, Ayşenur; Saral, Ayşegül; Nordmann, Patrice; Sandalli, Cemal (Elsevier Science Inc, 2014)Pseudomonas aeruginosa isolates were collected form a Turkish hospital. Antimicrobial susceptibility was performed using the Vitek 2 Compact system, and 24 isolates were categorized as multidrug resistant (n = 18), ... -
Cholesterol forms and traditional lipid profile for projection of atherogenic dyslipidemia: lipoprotein subfractions and erythrocyte membrane cholesterol
Uydu, Hüseyin Avni; Bostan, Mehmet; Atak, Mehtap; Yılmaz, Adnan; Demir, Adem; Akcan, Buket; Sümer, Fatih; Baltaş, Nimet; Karadağ, Zakir; Uğurlu, Yavuz; Örem, Asım (Springer, 2014)Atherogenic dyslipidemia characterized by abnormal changes in plasma lipid profile such as low high-density lipoprotein (HDL) and increased triglyceride (TG) levels is strongly associated with atherosclerotic diseases. We ... -
Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation
Üçüncü, Yılmaz; Çelik, Nuray; Öztürk, Cengiz; Türkoğlu, Murat; Çetin, Nihal; Koçkara, Nizamettin; Şener, Ebru; Dündar, Cihat; Arslan, Aynur; Doğan, Hasan; Kurt, Nezahat; Süleyman, Halis (Pergamon-Elsevier Science Ltd, 2015)Aims: This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside) and bromelain ... -
Chromosomal findings and sequence analysis of target exons of calcium-sensing receptor (CaSR) gene in patients with Sagliker syndrome
Tunç, Erdal; Demirhan, Osman; Sağlıker, Yahya; Yıldız, İsmail; Paylar, Nuray; Güzel, Ali İrfan (2017)Background/aim: Sagliker syndrome (SS) develops as a continuation of chronic kidney disease and secondary hyperparathyroidism conditions. It was thought that there are some genetic predisposition factors leading to SS. The ... -
Chronic prenatal exposure to the 900 megahertz electromagnetic field induces pyramidal cell loss in the hippocampus of newborn rats
Bas, O.; Odacı, E.; Mollaoğlu, H.; Üçok, K.; Kaplan, S. (Sage, 2009)Widespread use of mobile phones which are a major source of electromagnetic fields might affect living organisms. However, there has been no investigation concerning prenatal exposure to electromagnetic fields or their ... -
Clodronate changes neurobiological effects of pulsed magnetic field on diabetic rats with peripheral neuropathy
Mert, Tufan; Öçal, Işıl; Güzel, Ali İrfan; Günay, İsmail (Taylor & Francis Ltd., 2013)Several studies have reported that pulsed magnetic fields (PMFs) can be a choice of therapy for diabetic peripheral neuropathy. However, the exact underlying mechanism of PMF is still not known. The purpose of this study ... -
Cloning and expression of beta-1,3-glucanase gene from cellulosimicrobium cellulans in escherichia coli DH5a
Özcan, Bahri Devrim; Özcan, Numan; Baylan, Makbule; Güzel, Ali İrfan (Kafkas Univ, Veteriner Fakultesi Dergisi, 2013)In this study, beta-1,3-glucanase gene of Cellulosimicrobium cellulans was amplified by PCR and cloned in pUC18 cloning vector to construct the recombinant plasmids pTEG5 and pTEG11. the recombinant plasmids pTEG5 and ... -
Cloning and expression of cellulosimicrobium cellulans beta-1,3-glucanase gene in lactobacillus plantarum to create new silage inoculant for aerobic stability
Özcan, Bahri Devrim; Özcan, Numan; Baylan, Makbule; Güzel, Ali İrfan (Kafkas Univ, Veteriner Fakultesi Dergisi, 2013)In this study, the recombinant plasmid pTE353-beta G was created by inserting the p353-2 cryptic plasmid region of pLP3537 into pTEG5 recombinant plasmid contains pUC18 and beta-1,3-glucanase gene of Cellulosimicrobium ... -
Co-existance of ISABA1/BLA(OXA-51/23) is increasing in carbapenem rersistant acinetobacter baumannii isolates in Turkey
Uzunoğlu, Emel; Direkel, Şahin; Koçbıyık, Merve; Uludağ, Selma Keleş; Çiçek, Ayşegül Çopur (Carbone Editore, 2017)Introduction: Carbapenem resistant Acinetobacter baumannii (A. baumannii) strains are challenging topics for hospitals. We determined the antibiotic susceptibilities and genetic resistance mechanisms of 135 A. baumannii ... -
Common variants rs3815188 and rs1043994 on notch3 gene confer susceptibility to lung cancer: A hospital-based case-control study
Yağcı, Emine; Değirmenci, İrfan; Özbayer, Cansu; Ak, Güntulu; Saydam, Faruk; Metintaş, Muzaffer (Begell House Inc, 2019)The Notch signaling pathway is a mechanism that plays a role in the determination of cell fate during cell development. Signals between neighbor cells are amplified through the Notch receptors. Notch activity is related ... -
A comparative investigation of the nephrotoxic effects of various antihypertensive drugs in rats: biochemical and histopathological analysis
Malkoç, İsmail; Altunkaynak, Konca; Turan, Mehmet İbrahim; Gürsan, Nesrin; Hacımüftüoğlu, Ahmet; Akçay, Fatih; Üçüncü, Yılmaz; Süleyman, Halis (Carbone Editore, 2014)Aims: Hypertension is known to cause potentially fatal kidney damage. However, it is unclear whether long-term use of antihypertensive drugs establishes any toxic effect on the kidney. This study investigate whether ... -
Comparison of a novel antigen detection test with reverse transcription polymerase chain reaction assay for laboratory diagnosis of SARS-CoV-2 infection
Cirit, Osman Sezen; Mutlu, Esvet; Sancak, Banu; Kocagöz, Tanıl; Can, Özge; Çiçek, Candan; Sayıner, Ayça Arzu; Appak, Özgür; Uyar, Neval Yurttutan; Külah, Canan; Çiçek, Ayşegül Çopur; Özgümüş, Osman Birol; Altıntop, Yasemin Ay; Saatçi, Esma; Karslıgil, Tekin; Zer, Yasemin; Özen, Nevgün Sepin; Çekin, Yeşim; Karahan, Zeynep Ceren; Evren, Ebru; Karakoç, Ayşe Esra; Orhan, Sultan Gülbahçe; Mutlu, Derya; Bozdemir, Tuğba; Çaycı, Yeliz Tanrıverdi; Çınar, Canberk; Taşbakan, Meltem; Mert, Merve; Çınar, Ece; Kutlusoy, Oya Özlem Eren; Kocagöz, Sesin; Ertürk, Ayşe; Çelik, İlhami; Mete, Ayşe Özlem; Eneyli, Müge Günalp; Akdemir, İrem; Karakök, Taliha; İnan, Dilara; Atilla, Aynur; Taflan, Şevket Onur; Yörük, Kağan Etka (Springer, 2022)Molecular diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by real-time reverse transcription polymerase chain reaction (RT-PCR) in respiratory specimens is considered the gold standard method. ...