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Toplam kayıt 1429, listelenen: 1255-1274
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Synthesis and in vitro urease inhibition of some novel benzimidazole-based hydrazones
(Wiley, 2019)A novel series of N '-(substituted benzylidene)-2-(5,6-dichloro-2-methyl-1H-benzimidazol-1-yl)acetohydrazides and N '-(1-(substituted phenyl)ethylidene)-2-(5,6-dichloro-2-methyl-1H-benzimidazol-1-yl)acetohydrazides were ... -
Synthesis and in vitro α-glucosidase and cholinesterases inhibitory actions of water-soluble metallophthalocyanines bearing ({6-[3-(diethylamino)phenoxy]hexyl}oxy groups
(TUBITAK, 2022)In this paper, we have prepared peripherally tetra-({6-[3-(diethylamino)phenoxy]hexyl}oxy substituted cobalt(II), copper(II), manganese(III) phthalocyanines (3, 4, 5) and their water-soluble derivatives (3a, 4a, 5a). Then, ... -
Synthesis and kinetics studies of N '-(2-(3,5-disubstituted-4H-1,2,4-triazol-4-yl)acetyl)-6/7/8-substituted-2-oxo-2H-chromen-3-carbohydrazide derivatives as potent antidiabetic agents
(Wiley-V C H Verlag Gmbh, 2019)A novel series of N '-(2-(3,5-disubstituted-4H-1,2,4-triazol-4-yl)acetyl)-6/7/8-substituted-2-oxo-2H-chromen-3-carbohydrazides were synthesized and studied for their alpha-glucosidase inhibition activity. Most of the ... -
Synthesis and molecular docking studies of novel triazole derivatives as antioxidant agents
(Bentham Science Publ Ltd, 2020)A series of 1,2,4-triazole and 1,2,4- thiadiazole derivatives were prepared starting from ethyl 4-(3-methyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)benzoate. Firstly, both ethyl ester groups were simultaneously transformed ... -
Synthesis and molecular docking studies of potent urease inhibitors based on benzoxazole scaffold
(Wiley-V C Verlag GMBH, 2021)In this study, we report the synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzoxazole derivatives. The title compound in the series namely (2-(benzo[d]oxazol-2-ylthi ... -
Synthesis and molecular docking study of some 5,6-dichloro-2cyclopropyl-1H-benzimidazole derivatives bearing triazole, oxadiazole, and imine functionalities as potent inhibitors of urease
(Pergamon-Elsevier Science Ltd, 2017)A new series of benzimidazole compounds including hydrazinecarbothioamide, 1,2,4-triazole, 1,3,4-oxadiazole and imine function were synthesized starting from 5,6-dichloro-2-cyclopropyl-1H-benzimidazole. All of the benzimidazole ... -
Synthesis and molecular docking study of some novel 2,3-disubstituted quinazolin-4(3H)-one derivatives as potent inhibitors of urease
(Academic Press Inc Elsevier Science, 2018)A new series of 2,3-disubstituted quinazolin-4(3H)-one compounds including oxadiazole and furan rings was synthesized. Their inhibitory activities on urease were assessed in vitro. All newly synthesized compounds exhibited ... -
Synthesis and pancreatic lipase inhibitory activities of some 1,2,4-triazol-5(3)-one derivatives
(Wiley, 2020)In this study, starting from 4-amino-5-(4-chlorobenzyl)-2,4-dihydro-3H-1,2,4-triazole-3-one (1), the 4-Amino-5-(4-chlorobenzyl)-2-undecyl-2,4-dihydro-3H-1,2,4-triazol-3-one (2) was first synthesized and this compound was ... -
Synthesis and pharmacological activities of some new 2-[1-Heptyl-3-(4-methoxybenzyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl] acetohydrazide derivatives
(Walter de Gruyter Gmbh, 2014)In the present investigation, the key intermediate acetohydrazide derivative 5 was synthesized starting from 3-(4-methoxybenzyl)-4-amino-4,5-dihydro-1,2,4-triazol-5-one (1) by a four-step reaction. Thiosemicarbazides 6a-f ... -
Synthesis and properties of triazol-5-one substituted phthalocyanines by microwave irradiation
(TÜBİTAK, 2006)Triazol-5-one substituted phthalocyanines were prepared quickly by the reaction of 4-nitrophthalonitrile with anhydrous metal salts in DBU (1,8-diazabicyclo[5,4,0]undec-7-ene) and DMAE (dimethylaminoethanol) by microwave ... -
Synthesis and solvent-dependent photophysics of a novel fluorescent triazole-coumarin-based dye
(Wiley, 2020)Synthesis of a new coumarin-triazole-based dye and its photophysical parameters such as absorption, fluorescence emission, and fluorescence quantum yield were investigated. Studies have shown that the present dye has ... -
Synthesis and spectroscopic characterization of novel methoxy bridged benzimidazolyl-substituted phthalocyanines as potent inhibitors of urease
(Pergamon-Elsevier Science Ltd, 2020)In this study, novel peripherally 4-[(1H-benzimidazol-1-yl)methoxy] substituted Zn(II) (3) Cu(II) (4) and Co(II) (5) phthalocyanines were prepared and their structures were characterized spectroscopically. the light ... -
Synthesis and spectroscopic studies of homo-binuclear, alkoxo bridged homo- and hetero-tetranuclear metal complexes of a bis-N 2O 4 Schiff base ligand derived from ethanolamine and macroacyclic tetranaphthaldehyde
(Elsevier, 2011)Three new homo-binuclear Ni(II), Cu(II), Zn(II) complexes (2-4), homo-tetranuclear Cu(II) complex (5), and hetero-tetranuclear Cu(II)-Ni(II) complex (6) of a macroacyclic potentially bis-hexadentate N 2O 4 Schiff base have ... -
Synthesis and study of alpha-glucosidase inhibitory, antimicrobial and antioxidant activities of some benzimidazole derivatives containing triazole, thiadiazole, oxadiazole, and morpholine rings
(Springer, 2015)A new series of 2-(4-bromobenzyl)- and 2-(4-fluorobenzyl)-1H-benzimidazole derivatives containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and morpholine rings has been synthesized. the structures of the newly ... -
Synthesis and study of antitumor activity of some new 2-(4-methoxybenzyl)-1h-benzimidazole derivatives bearing triazole, oxadiazole and ethanol moiety
(Editura Acad Romane, 2016)A series of novel 1,2-disubstituted benzimidazole derivatives containing hydrazinecarbothioamide (7a-c), 1,2,4-triazole (8a-c) and 1,3,4-oxadiazole (5) moiety were synthesized starting from 2-(4-methoxybenzyl)-1H-benzimidazole. ... -
Synthesis and urease inhibition activities of some new schiff bases benzimidazoles containing thiophene ring
(Springer, 2024)Objective: Schiff bases are significant pharmacophores and show varied biological applications such as antiurease, antidiabetic, antioxidant, antifungal, antibacterial, and anticancer. In this study, new Schiff bases ... -
Synthesis and urease inhibition studies of some new quinazolinones
(Wiley, 2021)In this study, novel quinazolinones were designed, synthesized, characterized by FT-IR, H-1-NMR, C-13-NMR spectral data, and LC-MS. New compounds inhibitory activities on urease were assessed. All of the compounds exhibited ... -
Synthesis and urease inhibition study of some new quinazolinone derivatives bearing triazole, thiadiazole, and piperazine moiety
(Wiley, 2018)A new series of 2,3-disubstituted quinazolin-4(3H)-one derivatives bearing triazole and thiadiazole nucleus has been synthesized and then screened for their urease inhibition properties. All synthesized compounds showed ... -
Synthesis of 1,2,4-Triazole derivatives and determination of protonation constant
(2009)A microwave irradiation method has been developed for the synhesis of some 1,2,4-triazole derivatives using environmentally benign solvent ethanol in open vessels. Twelve 1,2,4-triazole derivatives were synthesized in good ... -
Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine Derivatives
(MDPI, ST ALBAN-ANLAGE 66, 2005)Iminoester hidroklorürler 1 sentezlenmiştir. Bu bileşikler daha sonra ester etoksikarbonil hidrazonlar 2'ye dönüştürüldü ve bunlardan sırasıyla yeni bir ikame edilmiş 4-amino-4,5-dihidro-lH-1,2,4-triazol-5-onlar, 3 serisi ...
