Kurum Yazarı "Özil, Musa" Fen Edebiyat Fakültesi İçin Listeleme
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Rapid and efficient microwave-assisted synthesis of some new triazol-3-one derivatives
Menteşe, Emre; Özil, Musa; Karaoğlu, Şengül Alpay; Kahveci, Bahittin (Wiley, 2013)A growing body of literature has shown the effectiveness of using microwaves in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new triazol-3-ones via microwave ... -
Recent advances on smart glycoconjugate vaccines in infections and cancer
Anderluh, Marko; Berti, Francesco; Bzducha-Wrobel, Anna; Chiodo, Fabrizio; Colombo, Cinzia; Compostella, Federica; Durlik, Katarzyna; Ferhati, Xhenti; Holmdahl, Rikard; Jovanovic, Dragana; Kaca, Wieslaw; Lay, Luigi; Marinovic-Cincovic, Milena; Marradi, Marco; Özil, Musa; Polito, Laura; Reina, Jose Juan; Reis, Celso A.; Sackstein, Robert; Silipo, Alba; Svajger, Urban; Vanek, Ondrej; Yamamoto, Fumiichiro; Richichi, Barbara; van Vliet, Sandra J. (Wiley, 2021)Vaccination is one of the greatest achievements in biomedical research preventing death and morbidity in many infectious diseases through the induction of pathogen-specific humoral and cellular immune responses. Currently, ... -
Regioselective syntheses of 2-oxopyridine carbonitrile derivatives and evaluation for antihyperglycemic and antioxidant potential
Saleem, Faiza; Haider, Maham; Khan, Khalid Mohammed; Özil, Musa; Baltaş, Nimet; Ul-Haq, Zaheer; Qureshi, Urooj; Salar, Uzma; Taha, Muhammad; Hameed, Shehryar; Ullah, Nisar (Elsevier, 2023)A library of 2-oxopyridine carbonitriles 1-34 was synthesized by regioselective nucleophilic substitution reactions. In the first step, a one-pot multicomponent reaction yield pyridone intermediates. The resulting pyridone ... -
Silorane-based composite: Depth of cure, surface hardness, degree of conversion, and cervical microleakage in class II cavities
Kşsgöz, Adem; Ülker, Mustaf; Yeşilyurt, Cemal; Yoldaş, Oğuz Hamdi; Özil, Musa; Tanrıver, Mehmet (Wiley, 2011)Objective: The purpose of this study was to determine the depth of cure, degree of conversion (DC), hardness, and cervical sealing ability of silorane-based composite (Filtek Silorane [FS; 3M, Seefeld, Germany]) and to ... -
A simple and efficient synthesis of benzimidazoles containing piperazine or morpholine skeleton at C-6 position as glucosidase inhibitors with antioxidant activity
Özil, Musa; Parlak, Cansu; Baltaş, Nimet (Academic Press Inc Elsevier Science, 2018)A novel 2-(aryl)-6-morpholin-4-yl(or 4-methylpiperazin-1-yl)-1H-benzimidazole derivatives were designed and expeditiously synthesized starting from 5-morpholin-4-yl(or 4-methylpiperazin-1-yl)-2-nitroaniline with various ... -
A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies
Özil, Musa; Emirik, Mustafa; Etlik, Semiha Yılmaz; Ülker, Serdar; Kahveci, Bahittin (Academic Press Inc Elsevier Science, 2016)A novel series of benzimidazole derivatives were prepared starting from o-phenylenediamine and 4-nitro-o-phenylenediamine with iminoester hydrochlorides. Acidic proton in benzimidazole was exchanged with ethyl bromoacetate, ... -
Solvent-free synthesis of novel phthalocyanines containing triazole derivatives under microwave irradiation
Özil, Musa; Canpolat, Mutlu (Pergamon-Elsevier Science Ltd, 2013)An efficient microwave processing method has been developed for the synthesis of novel metal-free phthalocyanine and metallophthalocyanines containing 1,2,4-triazole-3-one derivatives under microwave irradiation in ... -
Studies on the protonation constants of some triazoles in ethanol-water mixtures
İslamoğlu, Fatih; Kahveci, Bahittin; Özil, Musa; Akyüz, Emine (Chemical Publishing Co., 2008)Several studies, involving the formation and investigation of biological activities of some triazoles derivatives. These derivatives have weak acidic properties. To gain more information about the effect of solvent on ... -
Synthesis and characterization of two new hydroxamic acids derivatives and their metal complexes. An investigation on the keto/enol, E/Z and hydroxamate/hydroxirnate forms
Adıgüzel, Ekrem; Yılmaz, Fatih; Emirik, Mustafa; Özil, Musa (Elsevier Science Bv, 2017)2-phenylbenzimidazole-N-acetohydroxamic acid (HL1), 2-phenylbenzimidazole-N-butanohydroxamic acid (HL2) and Ni(II), Cu(II), Zn(II) and Cd(II) metal complexes have been synthesized and characterized by elemental analyses, ... -
Synthesis and glutathione reductase inhibitory properties of 5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one's aryl Schiff base derivatives
Balaydın, Halis Türker; Özil, Musa; Şentürk, Murat (Wiley-V C H Verlag Gmbh, 2018)Glutathione reductase (GR) is responsible for the existence of the reduced glutathione (GSH) molecule, a crucial antioxidant against oxidative stress reagents. the antimalarial activities of some redox active compounds are ... -
Synthesis and molecular docking studies of novel triazole derivatives as antioxidant agents
Özil, Musa; Tacal, Güvan; Baltaş, Nimet; Emirik, Mustafa (Bentham Science Publ Ltd, 2020)A series of 1,2,4-triazole and 1,2,4- thiadiazole derivatives were prepared starting from ethyl 4-(3-methyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)benzoate. Firstly, both ethyl ester groups were simultaneously transformed ... -
Synthesis and molecular docking studies of potent urease inhibitors based on benzoxazole scaffold
Özil, Musa; Tuzcuoğlu, Özge; Baltaş, Nimet; Emirik, Mustafa (Wiley-V C Verlag GMBH, 2021)In this study, we report the synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzoxazole derivatives. The title compound in the series namely (2-(benzo[d]oxazol-2-ylthi ... -
Synthesis and properties of triazol-5-one substituted phthalocyanines by microwave irradiation
Kahveci, Bahattin; Şaşmaz, Selami; Özil, Musa; Kantar, Cihan; Koşar, Başak; Büyükgüngör, Orhan (TÜBİTAK, 2006)Triazol-5-one substituted phthalocyanines were prepared quickly by the reaction of 4-nitrophthalonitrile with anhydrous metal salts in DBU (1,8-diazabicyclo[5,4,0]undec-7-ene) and DMAE (dimethylaminoethanol) by microwave ... -
Synthesis of 5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-one's aryl Schiff base derivatives and investigation of carbonic anhydrase and cholinesterase (AChE, BuChE) inhibitory properties
Özil, Musa; Balaydın, Halis Türker; Şentürk, Murat (Academic Press Inc Elsevier Science, 2019)Carbonic anhydrase enzymes (EC 4.2.1.1, CAs) are metalloenzyme families that catalyze the rapid conversion of H2O and CO2 to HCO3- and H+. CAs are found in different tissues where they participate in various significant ... -
Synthesis of benzimidazoles containing piperazine ring as potential therapeutic agents against diabetes mellitus and antioxidant activities
Özil, Musa; Khan, Khalid Mohammed; Baltaş, Nimet; Wadood, Abdul; Samad, Abdus; Kahveci, Bahittin (Elsevier, 2024)We synthesized a novel 6-(4-substitue-piperazin-1-yl)-2-aryl-1H-benzimidazole derivatives starting from 5-(4-substitue-piperazin-1-yl)-2-nitroaniline with different aldehydes. A quick "onepot" nitro reductive cyclization ... -
Synthesis of novel triazol compounds containing isatin as potential antibacterial and antifungal agents by microwave and conventional methods
Özil, Musa; Menteşe, Emre; Yılmaz, Fatih; İslamoğlu, Fatih; Kahveci, Bahittin (Sage Publishing, 2011)Microwave irradiation has been used to accelerate the conversion of isatin (1a) and 5-nitroisatin (1b) into their Schiff bases 3-[5?-aryl(alkyl)- 2?,4?-dihydro-1?,2?,4?-triazol-3?-on- 4?-yl]iminoisatin (3a-g) and ...