Kurum Yazarı "Karaoğlu, Şengül Alpay" Fen Edebiyat Fakültesi İçin Listeleme
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New potential monotherapeutic candidates for helicobacter pylori: Some pyridinazo compounds having both urease enzyme inhibition and anti-helicobacter pylori effectiveness
Kantar, Cihan; Baltaş, Nimet; Karaoğlu, Şengül Alpay; Şaşmaz, Selami (Springer, 2021)To contribute to the monotherapeutic approach to Helicobacter pylori, some new pyridinazo compounds containing natural phenols such as eugenol and guaiacol were synthesized and their antioxidant capacities, urease enzyme ... -
Novel fluoroquinolones containing 2-arylamino-2-oxoethyl fragment: Design, synthesis, evaluation of antibacterial and antituberculosis activities and molecular modeling studies
Kulabaş, Necla; Türe, Aslı; Bozdeveci, Arif; Krishna, Vagolu Siva; Karaoğlu, Şengül Alpay; Sriram, Dharmarajan; Küçükgüzel, İlkay (Wiley, 2022)Novel substituted fluoroquinolone derivatives, compounds 6-20 were designed, synthesized, and evaluated for antituberculosis and antibacterial activity. Antibacterial activities of the compounds were determined and compound ... -
Novel imidazo[2,1-b] [1,3,4]thiadiazole (ITD) hybrid compounds: Design, synthesis, efficient antibacterial activity and antioxidant effects
Taflan, Ebru; Bayrak, Hacer; Er, Mehtap; Karaoğlu, Şengül Alpay; Bozdeveci, Arif (Academic Press Inc Elsevier Science, 2019)In this study, novel imidazo[2,1-b] [1,3,4]thiadiazole (ITD) compounds were synthesized and their antimicrobial and antioxidant capacity was examined. the C-2 position of the ITD structure was fixed with the 3,4-hydroxybenzene ... -
PCR-based detection of the honeybee tracheal mite (Acarapis woodi) in Turkiye
Akpınar, Rahşan Koç; Sevim, Ali; Sevim, Elif; Kaya, Selma; Türlek, Şakir Önder; Aydın, Coşkun; Karaoğlu, Şengül Alpay; Çelik, Sema Nur; Bozdeveci, Arif; Güven, Gökhan; Küçükoğlu, Bilal; Yaldız, Murat; Aydın, İsmail (Springer, 2023)Acarapis woodi (Rennie 1921) (Acari: Tarsonemidae) is one of the mites that settles in the respiratory system of honeybees (Apis mellifera L. (Hymenoptera, Apidae)) and distributed throughout the world. It causes significant ... -
Phenolic acid contents of kale (Brassica oleraceae L. var. acephala DC.) extracts and their antioxidant and antibacterial activities
Ayaz, Faik Ahmet; Hayırlıoğlu-Ayaz, Sema; Karaoğlu, Şengül Alpay; Grúz, Jiři; Valentová, Kateřina; Ulrichová, Jitka; Strnad, Miroslav (Elsevier, 2008)Nine phenolic acids were identified and quantified by HPLC-MS in leaves and 10 in seeds of kale (black cabbage). The free, ester (methanol-soluble), glycoside and ester-bound (methanol-insoluble) phenolic acid contents of ... -
Phenolic components and antioxidant activity of prunus spinosa from Gumushane, Turkey
Aliyazıcıoğlu, Rezzan; Yıldız, Oktay; Şahin, Hüseyin; Eyüpoğlu, Ozan Emre; Özkan, Mehtap Tuğçe; Karaoğlu, Şengül Alpay; Kolaylı, Sevgi (Springer, 2015)Blackthorn (Prunus spinosa L.) is a fruit of the genus Prunus from the family Rosaceae. It grows wild in various regions in Turkey (especially in central, north, west, and south Anatolia). It has numerous stems covered ... -
Phenylenediamine, salicylic acid, stoichiometry, formation constant, speplot, metal complexes
Tosun, Gonca; Kahriman, Nuran; Çoskunçelebi, Kamil; Genç, Hasan; Karaoğlu, Şengül Alpay; Yaylı, Nurettin (2011)The present work describes the chemical composition and antimicrobial activity of the essential oil of Campanula olympica Boiss. which was isolated from the all parts of the plant by hydrodistillation and analyzed by GC-FID ... -
Phytochemicals, antimicrobial, and sporicidal activities of moss, Dicranum polysetum Sw., against certain honey bee bacterial pathogens
Karaoğlu, Şengül Alpay; Yaylı, Nurettin; Akpınar, Rahşan; Bozdeveci, Arif; Erik, İshak; Suyabatmaz, Şeyma; Korkmaz, Büşra; Batan, Nevzat; Kaya, Selma; Nisbet, Cevat; Güler, Ahmet (Springer, 2023)Beekeeping is an important agricultural and commercial activity globally practiced. Honey bee is attacked by certain infectious pathogens. Most important brood diseases are bacterial including American Foulbrood (AFB), ... -
Pollen analysis, chemical composition and antibacterial activity of Anatolian chestnut propolis collected from Yıgılca region
Kekeçoğlu, Meral; Sönmez, Emine; Acar, Merve Kambur; Karaoğlu, Şengül Alpay (Pleiades journals, 2021)Abstract: The purpose of this study is to examine the antimicrobial and antifungal activity of propolis samples of Yıgılca honey bee against Gram-positive and Gram-negative bacteria and yeast-like fungi. For this purpose ... -
Preparation and antimicrobial activity evaluation of some quinoline derivatives containing an azole nucleus
Özyanık, Muhammet; Demirci, Serpil; Bektaş, Hakan; Demirbaş, Neslihan; Demirbaş, Ahmet; Karaoğlu, Şengül Alpay (2012)Quinoline-2-carbohydrazide (2) obtained from quinaldic acid (1) was converted to the corresponding carbothioamide 3 and carboxamide 6 by treatment with benzyliso(thio)cyanate. The basic treatment of 3 and 6 yielded the ... -
Prevalence and phylogenetic analysis of Ascosphaera apis (Maassen ex Claussen) LS Olive & Spiltoir (1955) isolates from honeybee colonies in Turkey
Sevim, Ali; Akpınar, Rahşan; Karaoğlu, Şengül Alpay; Bozdeveci, Arif; Sevim, Elif (Springer, 2022)Ascosphaera apis (Maassen ex Claussen) Olive et Spiltoir is a causal agent of chalkbrood disease and is widely found in mainly honeybee colonies worldwide. Chalkbrood disease rarely causes colony death, but severe infections ... -
Purification and characterization of an extracellular lipase from Mucor hiemalis f. corticola isolated from soil
Ülker, Serdar; Karaoğlu, Şengül Alpay (Elsevier, 2012)We have screened 39 microfungi isolates originated from soil in terms of lipolytic activity. Out of all screened, a novel strain of Mucor hiemalis f. corticola was determined to have the highest lipase activity. The ... -
Quinolone-rhodanine hybrid compounds: Synthesis and biological evaluation as anti-bacterial agents
Cebeci, Yıldız Uygun; Karaoğlu, Şengül Alpay (Wiley, 2022)As potential antimicrobial agents, 4-fluoroaniline and diethyl (ethoxymethylene)malonate were used to efficiently synthesize a new quinolone (3-9) series. The (HNMR)-H-1 and C-13 NMR, IR, mass spectrometry, and elemental ... -
Rapid and efficient microwave-assisted synthesis of some new triazol-3-one derivatives
Menteşe, Emre; Özil, Musa; Karaoğlu, Şengül Alpay; Kahveci, Bahittin (Wiley, 2013)A growing body of literature has shown the effectiveness of using microwaves in chemical reactions. The aim of this study is to demonstrate a rapid and highly efficient synthesis of some new triazol-3-ones via microwave ... -
Reduction, Mannich reaction, and antimicrobial activity evaluation of some new 1,2,4-triazol-3-one derivatives
Fandaklı, Seda; Başoğlu, Serap; Bektaş, Hakan; Yolal, Meltem; Demirbaş, Ahmet; Karaoğlu, Şengül Alpay (TÜBİTAK, 2012)Ethyl[4-arylmethyleneamino-3-(4-metylphenyl)-5-oxo-4,5-dihydro-1H -1,2,4-triazole-1-yl]acetates (3a-e and 10a-d) were obtained starting from 4-amino-2,4-dihydro-3H -1,2,4-triazol-3-ones (1 and 9) in 2 steps. The treatment ... -
Salt stress resilience potential of a fungal inoculant isolated from tea cultivation area in maize
Durmuş, Nuran; Yesilyurt, Abdullah Muhammed; Pehlivan, Necla; Karaoğlu, Şengül Alpay (Springer, 2017)Agriculture needs to be sustained by organic processes in current era as population explosion energy and the number of individuals undernourished are raising public concerns. Global warming poses additional threat by lifting ... -
Some azo dyes containing eugenol and guaiacol, synthesis, antioxidant capacity, urease inhibitory properties and anti-helicobacter pylori activity
Kantar, Cihan; Baltaş, Nimet; Karaoğlu, Şengül Alpay; Şaşmaz, Selami (Editura Acad Romane, 2018)There are many studies about azo compounds at literature. However, antioxidant capacity, urease inhibitory and anti-Helicobacter pylori activity properties are not well known. Therefore, some azo dyes containing eugenol ... -
Some schiff bases containing eugenol and guaiacol: Comparison of urease inhibition and anti-helicobacter pylori activities with Its azo analogs
Kantar, Cihan; Baltaş, Nimet; Karaoğlu, Şengül Alpay; Şaşmaz, Selami (Springer, 2024)To improve and develop our monotherapeutic approach for Helicobacter pylori infection, some Schiff base compounds containing eugenol and guaiacol were synthesized and their antioxidant capacities, urease enzyme inhibition, ... -
Structure-based hybridization, microwave prompted synthesis and biological evaluation of novel 4-(2-fluoro-4-nitrophenyl)morpholine derivatives
Cebeci, Yıldız Uygun; Demirbaş, Neslihan; Özdemir, Serap Başoğlu; Bayrak, Hacer; Demirbaş, Ahmet; Aksakal, Fatma; Karaoğlu, Şengül Alpay (Bentham Science Publ Ltd, 2018)1,3,4-oxadiazole-2-thiole 6 was obtained from 4-(2-fluoro-4-nitrophenyl)morpholine (2) by the reduction of its nitro group and the sequential treatment of the resulting amine with ethyl bro-moacetate, hydrazine hydrate, ... -
Syntheses and biological activities of new hybrid molecules containing different heterocyclic moieties
Ceylan, Şule; Bektaş, Hakan; Bayrak, Hacer; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay; Ülker, Serdar (Wiley, 2013)4-Aryl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-(thi)oles 5-7, obtained starting from nicotinic acid hydrazide were converted to the corresponding Mannich bases 12-24 by the reaction with several heterocyclic amines in the ...