Kurum Yazarı "Emirik, Mustafa" FEF, Biyoloji Bölümü Koleksiyonu İçin Listeleme
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Developing effective antimicrobial agents: synthesis and molecular docking study of ciprofloxacin-benzimidazole hybrids
Menteşe, Emre; Yılmaz, Fatih; Menteşe, Meltem; Beriş, Fatih Şaban; Emirik, Mustafa (Wiley, 2024)In this study, we designed and synthesized some new ciprofloxacin-benzimidazole hybrid compounds and evaluated them for their antimicrobial activity against four Gram-positive (B. subtilis, B. megaterium, E. faecalis and ... -
Molecular docking studies and synthesis of novel bisbenzimidazole derivatives as inhibitors of alpha-glucosidase
Özil, Musa; Emirik, Mustafa; Beldüz, Ali; Ülker, Serdar (Pergamon-Elsevier Science Ltd, 2016)A series of bisbenzimidazole derivatives starting from o-phenylenediamine and 4-nitro-o-phenylenediamine were prepared with oxalic acid. Most of the reactions were conducted using both the microwave and conventional methods ... -
Paeoniflorigenone purified from Paeonia daurica roots potently inhibits viral and bacterial DNA polymerases: investigation by experimental validation and docking simulation
Demir, Adem; Turumtay, Halbay; Emirik, Mustafa; SandalIı, Cemal; Kanbolat, Şeyda; Özgen, Ufuk; Turumtay, Emine Akyüz (Springer Birkhauser, 2019)The methanolic extracts from fruit, leaf, stem and roots of Paeonia daurica subsp. macrophylla (P. daurica) were investigated for inhibitory effect on replicative bacterial (PolC and DnaE2) and viral (MMLV-RT from Moloney ... -
A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies
Özil, Musa; Emirik, Mustafa; Etlik, Semiha Yılmaz; Ülker, Serdar; Kahveci, Bahittin (Academic Press Inc Elsevier Science, 2016)A novel series of benzimidazole derivatives were prepared starting from o-phenylenediamine and 4-nitro-o-phenylenediamine with iminoester hydrochlorides. Acidic proton in benzimidazole was exchanged with ethyl bromoacetate, ...