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Küçük Resim

Antimicrobial resistance patterns and integron carriage of escherichia coli isolates causing community-acquired infections in Turkey 

Çiçek, Ayşegül Çopur; Özgümüş, Osman Birol; Saral, Ayşegül; Sandallı, Cemal (Korean Soc Laboratory Medicine, 2014)
We aimed to observe antimiCrobial resistance patterns and integron carriage of Escherichia coli isolates causing community-acquired infections. Two hundred sixty-eight E. coli strains were obtained from outpatients with ...
Küçük Resim

Molecular docking, synthesis and biological evaluation (enzyme inhibition, antimicrobial and antioxidant) of methoxy benzoin/benzil/stilbenoid derivatives 

Yaylı, Nurettin; Kahriman, Nuran; Kılıç, Gözde; Serdaroğlu, Vildan; Aliyazıcıoğlu, Rezzan; Sellitepe, Hasan Erdinç; Karaoğlu, Şengül Alpay; Yılmaz, Gizem Tatar (ACG Publications, 2022)
In this study. methoxy benzoin compounds (1-10) were synthesized from the corresponding aromatic aldehydes based on a screening of biological activity. Oxidation and reduction of benzoins (1-10) yielded the corresponding ...
Küçük Resim

The phenolic composition, aroma compounds, physicochemical and antimicrobial properties of Nigella sativa L. (black cumin) honey 

Kolaylı, Sevgi; Kazaz, Gamze; Özkök, Aslı; Keskin, Merve; Kara, Yakup; Kandur, Esra Demir; Ertürk, Ömer (Springer, 2022)
Honey is an important bee product with its nutritional and medicinal properties. Characterization of different monofloral honey has importance for focusing on honey's biocomponents and the potential use of its medicinal ...
Küçük Resim

Synthesis of hydroxy benzoin/benzil analogs and investigation of their antioxidant, antimicrobial, enzyme inhibition, and cytotoxic activities 

Yaylı, Nurettin; Kılıç, Gözde; Çelik, Gözde; Kahriman, Nuran; Kanbolat, Şeyda; Bozdeveci, Arif; Karaoğlu, Şengül Alpay; Aliyazıcıoğlu, Rezzan; Sellitepe, Hasan Erdinç; Doğan, İnce Selin; Aydın, Ali (Scientific Technical Research Council Turkey - TUBİTAK, 2021)
In this study, hydroxy benzoin (1-7), benzil (8-14), and benzoin/benzil-O-beta-D-glucosides (15-25) were synthesized to investigate their biological activities. An efficient method for synthesizing hydroxy benzoin compounds ...
Küçük Resim

Antimicrobial, cytotoxic, antiviral wffects, and apectroscopic characterization of metabolites produced by fusarium oxysporum YP9B 

Kılıç, Gözde; Tosun, Gonca; Bozdeveci, Arif; Erik, İshak; Öztürk, Elif; Reis, Rengin; Sipahi, Hande; Cora, Merve; Karaoğlu, Şengül Alpay; Yaylı, Nurettin (ACG Publications, 2021)
The goal of the work is to determine the bioactive pharmaceutical metabolites produced by the Fusarium oxysporum YP9B isolate. Ten new natural compounds were isolated from the ethyl acetate extract of the F. oxysporum YP9B ...
Küçük Resim

Do different substrates affect antioxidant properties and antimicrobial activity of Pleurotus ostreatus? 

Bozdeveci, Arif; Avcı, Sibel; Karaoğlu, Şengül Alpay; Can, Zehra; Pekşen, Aysun (2022)
The aim of this study is to determine the effect of growing substrates on the antioxidant properties and antimicrobial activities of Pleurotus ostreatus (Jacq.) P. Kumm. In the study, growing substrates were prepared ...
Küçük Resim

Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil 

Erik, İshak; Bozdal, Gözde; Şener, Sıla Özlem; Korkmaz, Büşra; Karaoğlu, Şengül Alpay; Terzioğlu, Salih; Yaylı, Nurettin (TUBITAK, 2022)
The essential oil (EO) of Cota tinctoria var. tinctoria was analyzed using GC-FID / MS. A total of 51 compounds were determined from this taxon, accounting for 99.79% in hydrodistillation. Monoterpenes were the primary ...
Küçük Resim

Synthesis, biological evaluation (antioxidant, antimicrobial, enzyme inhibition, and cytotoxic) and molecular docking study of hydroxy methoxy benzoin/benzil analogous 

Yaylı, Nurettin; Kılıç, Gözde; Kahriman, Nuran; Kanbolat, Şeyda; Bozdeveci, Arif; Karaoğlu, Şengül Alpay; Aliyazıcıoğlu, Rezzan; Sellitepe, Hasan Erdinç; Doğan, İnci Selin; Aydın, Ali; Tatar, Gizem (Academic Press Inc., 2021)
In this work, due to the biological activity evaluation, a series of hydroxy methoxy benzoins (1–8), benzils (10–16) and methoxy benzoin/benzil-O-β-D-glucosides (17–28) were synthesized. Antioxidant (FRAP, CUPRAC, DPPH), ...

Study of antıoxidant, antimicrobial and anti-xanthine oxidase activities of some 5,6-dimethyl-2-(substituted)-1h-benzimidazoles and their acylhydrazide derivatives 

Baltaş, Nimet; Beriş, Fatih Şaban; Menteşe, Emre (Raman Publ, 2017)
In this study, a series of 5,6-dimethy1-2-(4-fluoro/chloro/bromo/methyl/nitrobenzy1)-1Hbenzimidazoles were screened for their bovine milk xanthine oxidase (XO) inhibition, antioxidant and antimicrobial activities. Compounds ...
Küçük Resim

Biological evaluation and synthesis of new pyrimidine-2(1H)-ol/-thiol derivatives derived from chalcones using the solid phase microwave method 

Fandakli, Seda; Kahriman, Nuran; Yücel, Tayyibe Beyza; Karaoğlu, Şengül Alpay; Yaylı, Nurettin (Scientific Technical Research Council Turkey-Tubitak, 2018)
Twenty-five new hydroxy- and methoxy-substituted 4,6-diarylpyrimidin-2(1H)-ol (20-34) and 4,6-diarylpyrimidine-2(1H)-thiol derivatives (35-44) were synthesized from the reaction of the corresponding 1,3-diaryl-2-propene-1-one ...
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