Yazar "Serdaroğlu, Vildan" için FEF, Kimya Bölümü Koleksiyonu listeleme
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Diastereoselective synthesis, characterization, investigation of anticancer, antibacterial activities, in silico approaches and DNA/BSA binding affinities of novel pyrimidine-sugar derivatives
Kahriman, Nuran; Serdaroğlu, Vildan; Aydın, Ali; Türkmenoğlu, Burçin; Usta, Asu (Elsevier, 2023)Eighteen novel carbohydrate conjugates (1-9) and their tetra-O-acetyl derivatives (10-18) were synthesized in total and evaluated for their biological properties, including antimicrobial and anticancer functions, and ... -
New pyrimidine-N-β-D-glucosides: synthesis, biological evaluation, and molecular docking investigations
Kahriman, Nuran; Peker, Kıvanç; Serdaroğlu, Vildan; Aydın, Ali; Türkmenoğlu, Burçin; Usta, Asu; Yaylı, Nurettin (Scientific Technical Research Council Turkey, TÜBİTAK, 2023)In this study, syntheses of new pyrimidine-coupled N-beta-glucosides and tetra-O-acetyl derivatives were carried out. All glycoconjugates were investigated in comparison with known chemotherapeutic agents in terms of their ... -
Novel 2-amino-4-aryl-6-pyridopyrimidines and N-alkyl derivatives: Synthesis, characterization and investigation of anticancer, antibacterial activities and DNA/BSA binding affinities
Kahriman, Nuran; Peker, Kıvanç; Serdaroğlu, Vildan; Aydın, Ali; Usta, Asu; Fandaklı, Seda; Yaylı, Nurettin (Academic Press Inc Elsevier Science, 2020)A series of new 2-amino-4-aryl-6-pyridopyrimidines, and their N-alkyl bromide derivatives were designed and synthesized by employing methyl substituted azachalcones. These novel compounds were evaluated and compared to the ... -
Synthesis and biological evaluation of new 2,4,6-trisubstituted pyrimidines and their N-alkyl derivatives
Kahriman, Nuran; Serdaroğlu, Vildan; Peker, Kıvanç; Aydın, Ali; Usta, Asu; Fandaklı, Seda; Yaylı, Nurettin (Academic Press Inc Elsevier Science, 2019)A series of new 2,4,6-trisubstituted pyrimidines and their N-alkyl bromide derivatives were prepared based upon methoxy substituted azachalcones as the starting materials. All newly synthesized compounds were screened for ...