Ara
Toplam kayıt 21, listelenen: 11-20
In silico inhibition potential of artemisinin derivatives against SARS-CoV-2 main protease
(TUBİTAK Scientific & Technical Research Council Turkey, 2021)
The outbreak of COVID-19 caused by the SARS-CoV-2 virus has recently affected millions worldwide. The natural compounds obtained from medicinal plants have been proven to be the source of many treatments throughout history. ...
Potential therapeutic effect of turmeric contents against SARS-CoV-2 compared with experimental COVID-19 therapies: in silico study
(Taylor & Francis Inc, 2020)
Inspired by the 'There is no scientific evidence that turmeric prevents COVID-19' statement made by WHO, the protective or therapeutic potential of the compounds in turmeric contents was investigated against COVID-19 with ...
New 1,3,4-thiadiazol derivatives: Synthesis, computational study and X-Ray
(Elsevier, 2020)
In this study, 4-hydroxyphenyl-3H-1,2,4-triazol-3-one derivatives (la-d), cyanomethoxyphenyl-3-alkyl/aryl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-acetonitriles (2a-d) and bis amino-1,3,4-thiadiazol-5-alkyl/aryl-2,4-dihydro-3H ...
Synthesis, alpha-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives
(Academic Press Inc Elsevier Science, 2020)
In this study, a new series of 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives has been synthesized and screened for their alpha-glucosidase inhibitory potential. All molecules showed a considerable ...
Chalcone-based dipolar cycloaddition of novel heteroaromatic compounds: Their anticancer examination
(Elsevier, 2023)
In this study, new chalcone-isoxazole-based hybrid derivatives (12, 13, 18, and 21) and chalcone-triazole hybrid molecules (26) were synthesized using the click chemistry approach. Among these hybrid molecules, 12, 13, 21, ...
Metabolite profiling of Althaea officinalis by HPLC-DAD-MS with in silico and in vitro analysis for therapeutic potential
(Springer, 2023)
Althaea officinalis L. has been widely used traditionally as an herbal tea and for the treatment of cough, mucous membrane irritation, colds, and inflammation. Parts of the plant extracts were analyzed using HPLC-DAD and ...
Binuclear Cu(II), Ni(II) and Zn(II) complexes of hydrazone Schiff bases: Synthesis, spectroscopy, DFT calculations, and SOD mimetic activity
(Elsevier, 2023)
Two new salicylaldimine-based N-heterocyclic hydrazone ligands, N'-[(2-hydroxyphenyl) methylene]2-(2-phenyl-1H-benzimidazol-1-yl)acetohydrazone (H 2 L 1 ) and 2-[2-(3-chlorobenzyl)-1H-benzimidazol-1yl]-N'-[(2-(hydroxyimi ...
Benzimidazolone-piperazine/triazole/thiadiazole/furan/thiophene conjugates: Synthesis, in vitro urease inhibition, and in silico molecular docking studies
(Wiley, 2023)
This study describes the synthesis, in vitro urease inhibition, and molecular docking studies of benzimidazolone derivatives incorporating the piperazine, triazole, thiadiazole, furan, thiophene, and thiosemicarbazide ...
Stereo- and Regio-selective benzo- and Benzohalo-conduritols: Anti-diabetes & anti-tumor activity investigation, kinetic and molecular docking studies
(Elsevier, 2023)
In this study, benzoconduritols, benzohalogenoconduritol, and benzodihalogenoconduritols with conduritol-A and –C structures from oxo-norbornene derivative endo-10 b, exo-11 b cleavaged by Lewis acids (BBr3, BCl3, BF3· ...
Developing effective antimicrobial agents: synthesis and molecular docking study of ciprofloxacin-benzimidazole hybrids
(Wiley, 2024)
In this study, we designed and synthesized some new ciprofloxacin-benzimidazole hybrid compounds and evaluated them for their antimicrobial activity against four Gram-positive (B. subtilis, B. megaterium, E. faecalis and ...