Ara
Toplam kayıt 77, listelenen: 51-60
Synthesis and urease inhibition study of some new quinazolinone derivatives bearing triazole, thiadiazole, and piperazine moiety
(Wiley, 2018)
A new series of 2,3-disubstituted quinazolin-4(3H)-one derivatives bearing triazole and thiadiazole nucleus has been synthesized and then screened for their urease inhibition properties. All synthesized compounds showed ...
Synthesis, molecular docking and biological evaluation of some benzimidazole derivatives as potent pancreatic lipase inhibitors
(Academic Press Inc Elsevier Science, 2018)
In this study, a new series of benzimidazole and bisbenzimidazole derivatives were prepared via the reaction of iminoester hydrochlorides and o-phenylenediamines and then screened for their lipase inhibition properties. ...
Synthesis and molecular docking study of some novel 2,3-disubstituted quinazolin-4(3H)-one derivatives as potent inhibitors of urease
(Academic Press Inc Elsevier Science, 2018)
A new series of 2,3-disubstituted quinazolin-4(3H)-one compounds including oxadiazole and furan rings was synthesized. Their inhibitory activities on urease were assessed in vitro. All newly synthesized compounds exhibited ...
Synthesis of some new Methoxy Bridged Benzimidazolyl-Substituted phthalocyanines as potent inhibitors of urease
(Elsevier Science Sa, 2018)
In this study, the novel peripherally 4-[(2-methyl-1H-benzimidazol-1-yl)methoxy] substituted Zn(II) (3) Cu(II) (4), Co(II) (5) phthalocyanines were prepared and their structures were characterized spectro-scopically. the ...
Crystal structure of 4-[(4-Ethyl-5-Phenyl-4H-1,2,4-Triazol-3-yl)sulfanyl]phthalonitrile
(Pleiades Publishing Inc, 2018)
The structure of the 4-[(4-ethyl-5-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl]phthalonitrile titled molecule is determined by means of X-ray diffraction. the title compound has weak inter- and intramolecular C-H...N-type hydrogen ...
Synthesis, antioxidant, and antibacterial activities of some new 2-(3-fluorobenzyl)-1H-benzimidazole derivatives
(Wiley, 2018)
A new series of 2-(3-fluorobenzyl)-1H-benzimidazole derivatives containing Schiff base, 1,3,4-oxadiazole, thiosemicarbazide, and 1,3,4-thiadiazole moiety was synthesized. All the synthesized compounds were investigated for ...
Novel 1,2,4-triazole substituted metallo-phthalocyanines: Synthesis, characterization and investigation of electrochemical and spectroelectrochemical properties
(Elsevier Science Bv, 2018)
The phthalonitrile compound (3) and peripherally tetra substituted zinc(II) (4), nickel (II) (5), iron (II) (6), cobalt (II) (7) and copper (II) (8) phthalocyanines were synthesized for the first time in this study. the ...
Synthesis of novel 2,3-disubstituted quinazolin-4(3H)-one derivatives containing hydrazone skeleton as potent urease inhibitors and their antimicrobial activities
(Wiley, 2019)
A new series of quinazolinones containing hydrazone moiety were synthesized, and their inhibitory activities on urease were assessed in vitro. Most of the compounds exhibited potent urease inhibitory activity. Among the ...
Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
(Academic Press Inc Elsevier Science, 2019)
A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ...
Synthesis and in vitro urease inhibition of some novel benzimidazole-based hydrazones
(Wiley, 2019)
A novel series of N '-(substituted benzylidene)-2-(5,6-dichloro-2-methyl-1H-benzimidazol-1-yl)acetohydrazides and N '-(1-(substituted phenyl)ethylidene)-2-(5,6-dichloro-2-methyl-1H-benzimidazol-1-yl)acetohydrazides were ...