Ara
Toplam kayıt 29, listelenen: 21-29
Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
(Academic Press Inc Elsevier Science, 2019)
A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ...
Synthesis, antioxidant and antiurease activities of some new 5,6-dichloro-2-(4-fluorobenzyl)-1H-benzimidazolle derivatives containing furan, oxadiazole, triazole and thiadiazole moieties
(Bentham Science Publ Ltd, 2019)
Background: Benzimidazoles and its derivatives have been attracting interest for many years because of their biological activities. Benzimidazoles containing different heterocyclic moieties have wide range of biological ...
Synthesis and characterization of ring-type and branched polymers including polyethylene glycols by "click" chemistry
(Springer International Publishing Ag, 2019)
Synthesis of ring-type (or branched) polymers including polyethylene glycols was archived via "click" chemistry of 5,6-diazido-2-benzyl-1H-benzimidazole (Di-N-3) [or triazidoacetohydrazide derivative (Tri-N-3)] and terminally ...
Synthesis, alpha-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives
(Academic Press Inc Elsevier Science, 2020)
In this study, a new series of 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives has been synthesized and screened for their alpha-glucosidase inhibitory potential. All molecules showed a considerable ...
Synthesis of some benzimidazole-thiophene hybrids as potential urease and lipase inhibitors
(Springer Link, 2023)
In this study, some benzimidazole-thiophene hybrid compounds containing isatin and salicyl moieties were synthesized and investigated for their urease and lipase inhibition properties. Most of the synthesized compounds ...
Developing effective antimicrobial agents: synthesis and molecular docking study of ciprofloxacin-benzimidazole hybrids
(Wiley, 2024)
In this study, we designed and synthesized some new ciprofloxacin-benzimidazole hybrid compounds and evaluated them for their antimicrobial activity against four Gram-positive (B. subtilis, B. megaterium, E. faecalis and ...
Synthesis of benzimidazoles containing piperazine ring as potential therapeutic agents against diabetes mellitus and antioxidant activities
(Elsevier, 2024)
We synthesized a novel 6-(4-substitue-piperazin-1-yl)-2-aryl-1H-benzimidazole derivatives starting from 5-(4-substitue-piperazin-1-yl)-2-nitroaniline with different aldehydes. A quick "onepot" nitro reductive cyclization ...
Green protocol: Catalyst-free synthesis of 2-substituted benzimidazoles under ultrasound irradiation
(Science Reviews 2000 Ltd, 2018)
The synthesis of 2-substituted benzimidazoles from the reaction of o-phenylenediamine and an imino ester hydrochloride with ultrasound irradiation is reported. The procedure has an eco-friendly and simple workup with good ...
Efficient synthesis of 2-[(3,4-dichlorophenyl)methyl]-1h-benzimidazole derivatives, and their α-glucosidase inhibitory and antioxidant activities
(Bentham Science Publishers, 2020)
In this work, some new 2-[(3,4-dichlorophenyl)methyl]-1H-benzimidazole derivatives containing different five-membered heterocycles like 1,3,4-oxadiazole, 1,3,4-triazole, and 1,3,4-thiadiazole moieties were designed and ...