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Toplam kayıt 296, listelenen: 81-90
Synthesis and acetylcholinesterase enzyme inhibition properties of axially disubstituted silicon phthalocyanines and their quaternized derivatives
(Elsevier, 2022)
In this paper, axial 1,3-bis[4-(4-acetylpiperazin-1-yl)phenoxy]propanoxy and {2-[4-(4-acetylpiperazin-1-yl)phenoxy]ethoxy}ethoxy groups substituted silicon(IV) phthalocyanines ( PP-D-Si, PP-OH2-Si) and their quaternized ...
Metallo-phthalocyanines containing triazole substituents: Synthesis, spectroscopic and photophysicochemical properties
(Taylor & Francis Ltd., 2022)
Magnesium(II) (4), lead(II) (5) and zinc(II) (6) phthalocyanines were prepared. The structures of 4-6 were confirmed by the spectroscopic characterization such as FT-IR, H-1-NMR, MALDI-TOF mass, UV-vis and fluorescence ...
Synthesis of novel thiosemicarbazone derivatives as antidiabetic agent with enzyme kinetic studies and antioxidant activity
(Taylor & Francis Ltd., 2022)
Novel thiosemicarbazone derivatives were synthesized via condensation reactions between the corresponding thiosemicarbazides and 4-(methylsulfonyl)acetophenone. The chemical structures of all compounds were elucidated by ...
Synthesis, biological evaluation and in silico studies of new pyrazoline derivatives bearing benzo[d]thiazol-2(3H)-one moiety as potential urease inhibitors
(Wiley, 2022)
Novel pyrazoline derivatives containing benzo[d]thiazol-2(3H)-one moiety were synthesized and screened for their inhibitory properties against urease, a clinically important metabolic enzyme. In vitro enzyme inhibition ...
Hydrazinyl thiazole linked indenoquinoxaline hybrids: Potential leads to treat hyperglycemia and oxidative stress; Multistep synthesis, alpha-amylase, and antioxidant activities
(Elsevier, 2022)
A library of hydrazinyl thiazole-linked indenoquinoxaline hybrids 1-36 were synthesized via a multistep reaction scheme. All synthesized compounds were characterized by various spectroscopic techniques including EI-MS ...
Developing a scaffold for urease inhibition based on benzothiazoles: Synthesis, docking analysis, and therapeutic potential
(Wiley-V C Verlag GMBH, 2021)
The synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzothiazole derivatives are reported. The title compounds in the two series, namely, 2-({5-[(benzothiazol-2-ylthio ...
Synthesis of water-soluble BODIPY dyes and investigation of their DNA interaction properties and cytotoxicity/phototoxicity
(Wiley, 2021)
In this study, water-soluble BODIPY dyes (BDPY-4, BDPY-5) bearing dimethylamino and diethylamino groups were synthesized for the first time. The DNA interaction and nuclease effect of two water-soluble BODIPY dyes were ...
Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review
(Elsevier, 2021)
N-heterocycles are important, not only because of their abundance, but above all because of their chemical, biological and technical significance. They play an important role in biological investigation such as anticancer, ...
Synthesis and biological evaluation of benzimidazolone bridged triheterocyclic compounds
(Wiley, 2021)
A new series of benzimidazolone bridged triheterocyclic compounds bearing thiosemicarbazide, thiadiazole, triazole, moieties was synthesized and then screened for their in vitro urease, alpha-glucosidase, and acetylcholinesterase ...
Synthesis and urease inhibition studies of some new quinazolinones
(Wiley, 2021)
In this study, novel quinazolinones were designed, synthesized, characterized by FT-IR, H-1-NMR, C-13-NMR spectral data, and LC-MS. New compounds inhibitory activities on urease were assessed. All of the compounds exhibited ...