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Microwave-assisted synthesis of novel 2,4-dihydro-5-[4-(trifluoromethyl) phenyl]-3h-1,2,4-triazol-3-ones and potentiometric determination of their pKa in nonaqueous solvents
(Wiley, 2010)
The novel 4-amino- or 4-aryl-substituted 2,4-dihydro-5-[(4-trifluoromethyl) phenyl]-3H-1,2,4-triazol-3-ones 3a-3g were synthesized by reaction of N-(ethoxycarbonyl)-4-(trifluoromethyl)benzenehydrazonic acid ethyl ester (2) ...