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The protective effects of perindopril against acute kidney damage caused by septic shock
(Springer/Plenum Publishers, 2021)
Acute kidney injury (AKI) resulting from septic shock caused by sepsis is an important health problem encountered at rates of 55-73%. Increasing oxidative stress and inflammation following sepsis is a widely observed ...
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
(Taylor & Francis Ltd., 2022)
Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ...
The protective effects of trimetazidine against ovary ischemia-reperfusion injury via the TLR4/Nf-kB signal pathway
(Wiley, 2022)
Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia, irreversible damage to ovarian functions and infertility. In this process, there is no approved medical treatment that can reduce the ...
The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation
(Verduci Editore, 2022)
OBJECTIVE: Sepsis is responsible for more than 5 million deaths worldwide every year. The purpose of this study was to use amifostine to reduce acute kidney injury developing as a result of sepsis. MATERIALS AND METHODS: ...
The effects of dexmedetomidine on early acute kidney injury in severely burned rats
(Verduci Publisher, 2023)
OBJECTIVE: Burns are a global
medical and economic problem. In addition to
high costs, the lengthy therapeutic process and
the emotional trauma experienced by patients
and their families indirectly worsen the socioeconomic ...