• Enhancing hepatocellular carcinoma surveillance: comparative evaluation of AFP, AFP-L3, DCP and composite models in a biobank-based case-control study 

  Demirtaş, Coşkun O.; Akın, Şehnaz; Karadağ, Demet Yılmaz; Yılmaz, Tuba; Çiftçi, Uğur; Huseynov, Javid; Bulte, Tuğba Tolu; Kaldırım, Yasemin Armutcuoğlu; Dilber, Feyza; Özdoğan, Osman Cavit; Eren, Fatih (MDPI (Multidisciplinary Digital Publishing Institute), 2025)

  Background/Objectives: Biomarkers such as lens agglutinin-reactive alpha-fetoprotein and des-gamma-carboxy prothrombin, as well as biomarker- and/or clinical-parameter-derived composite models (GALAD, GAAP, ASAP, aMAP, ...

• GDF-15 levels in gouty arthritis and correlations with decreasing renal function: a clinical study 

  Cüre, Osman; Yiğit, Ertuğrul; Yiğit, Merve Hüner; Uzun, Hakkı (MDPI (Multidisciplinary Digital Publishing Institute), 2025)

  Background/Objectives: Gouty arthritis (GA) is a chronic inflammatory disorder frequently linked to systemic inflammation and impaired kidney function. Growth differentiation factor-15 (GDF-15) has been suggested as a ...

• Immature platelet fraction as a sensitive biomarker in neonatal sepsis: diagnostic performance preceding thrombocytopenia 

  Er, İlkay; Arpa, Medeni (MDPI (Multidisciplinary Digital Publishing Institute), 2025)

  Background: Early and accurate diagnosis of neonatal sepsis remains a clinical challenge due to nonspecific signs and limitations of conventional biomarkers. The immature platelet fraction (IPF), a novel hematologic parameter ...

• Spontaneous tracheal fistulization of a progressive bronchogenic cyst: a four-year conservative follow-up case report 

  Şentürk Topaloğlu, Elvan; Topaloğlu, Ömer (Elsevier, 2025)

  ....

• The relationship between type D personality and quality of life in atrial fibrillation patients 

  Kayhan, Semiha Alkan; Dizdar, Ebru; Hanedan, Muhammet Onur; Karakişi, Sedat Ozan (Elsevier, 2025)

  Aim: This study aims to examine the relationship between type D personality and quality of life in atrial fibrillation (AF) patients. Background: AF patients are highly prone to psychological problems such as anxiety and ...

• The mediating role of somatic symptoms in the effect of depression on problem-solving skills 

  Sönmez, Doğancan; Bahçeci, Bülent (AVES, 2025)

  Background: Major depressive disorder (MDD) is a serious mental disorder that is common worldwide and is associated with somatic symptoms. Cognitive and behavioral problems caused by depression can negatively affect ...

• Association of serum copeptin levels with pulmonary complications and heart right ventricular functions in common variable immunodeficiency 

  Kılınç, Mehmet; Çölkesen, Fatih; Sadi Aykan, Filiz; Evcen, Recep; Yıldız, Eray; Feyzioğlu, Bahadır; Doğan, Metin; Alsancak, Yakup; Tatar, Sefa; Arslan, Şevket (BioMed Central Ltd, 2025)

  Background and aims: Common variable immunodeficiency (CVID) represents the most frequently diagnosed symptomatic primary immunodeficiency (PID), marked by a heterogeneous presentation involving infectious and non-infectious ...

• The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease 

  Eslam, Mohammed; Fan, Jian-Gao; Yu, Ming-Lung; Wong, Vincent Wai-Sun; Cua, Ian Homer; Liu, Chun-Jen; Tanwandee, Tawesak; Gani, Rino; Seto, Wai-Kay; Alam, Shahinul; Young, Dan Yock; Hamid, Saeed; Zheng, Ming-Hua; Kawaguchi, Takumi; Chan, Wah-Kheong; Payawal, Diana; Tan, Soek-Siam; Goh, George Boon-bee; Strasser, Simone I.; Viet, Hang Dao; Kao, Jia-Horng; Kim, Won; Kim, Seung Up; Keating, Shelley E.; Yılmaz, Yusuf; Kamani, Lubna; Wang, Chia-Chi; Fouad, Yasser; Abbas, Zaigham; Treeprasertsuk, Sombat; Thanapirom, Kessarin; Al Mahtab, Mamun; Lkhagvaa, Undram; Baatarkhuu, Oidov; Choudhury, Ashok Kumar; Stedman, Catherine A. M.; Chowdhury, Abhijit; Dökmeci, A Kadir; Wang, Fu-Sheng; Lin, Han-Chieh; Huang, Jee-Fu; Howell, Jess; Jia, Jidong; Alboraie, Mohamed; Roberts, Stuart K.; Yoneda, Masato; Ghazinian, Hasmik; Mirijanyan, Aram; Nan, Yuemin; Lesmana, Cosmas Rinaldi Adithya; Adams, Leon A.; Shiha, Gamal; Kumar, Manoj; Örmeci, Necati; Wei, Lai; Lau, George; Omata, Masao; Sarin, Shiv K.; George, Jacob (Springer, 2025)

  Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is the leading cause of liver disease worldwide. To address this, the Asian Pacific Association for ...

• Clinical and immunological prognostic factors with novel variants in a large cohort of diacylglycerol acyltransferase 1 deficiency 

  Yorgun Altunbaş, Melek; Kogler, Hubert; Abolhassani, Hassan; Akkuş, Erkan; Baştürk, Ahmet; Akkelle, Emre; Sayar, Ersin; Polat, Esra; Kara, Altan; Can, Salim; Frohne, Alexandra; Segarra-Roca, Anna; Jimenez-Heredia, Raul; Babayeva, Royala; Sefer, Asena Pınar; Kıykım, Ayça; Bilgiç Eltan, Sevgi; Karakoç-Aydıner, Elif; Özen, Ahmet; Beşer, Ömer Faruk; Boztuğ, Kaan; Rezaei, Nima; Barış, Safa (American Academy of Allergy, Asthma and Immunology, 2025)

  Background: Biallelic variants in diacylglycerol acyltransferase 1 (DGAT1) genegene have been implicated congenital diarrhea and protein-losing enteropathy. Insights into the immunopathologic features of this ultrarare ...

• The immediate effects of different types of tea consumption on ocular biometric and specular microscopic parameters in healthy subjects 

  Uzun, Feyzahan; Aydın, Emre; Akgöz, Hasan; Aslan, Mehmet Gökhan; Fındık, Hüseyin (AVES, 2025)

  Background: Tea ranks among the most popular beverages globally. In this study, we assessed the short-term changes in ocular biometric and specular microscopic parameters in healthy subjects following the consumption of ...

• Comorbidity of attention deficit hyperactivity disorder in young adults who had major depressive disorder 

  Yazıcı, Merve; Puşuroğlu, Meltem (King Faisal Specialist Hospital and Research Centre, 2025)

  BACKGROUND: The comorbidity of Major Depressive Disorder (MDD) and Attention Deficit Hyperactivity Disorder (ADHD) in adults is well recognized. The role of ADHD in the etiology of MDD, as well as the overlap of genetic ...

• Diagnostic value of dual-energy ct iodine mapping in differentiating malignant and benign cervical lymphadenopathies 

  Başaran, Mustafa; Çeliker, Fatma Beyazal; Çeliker, Metin; Panç, Kemal; Gürün, Enes (Wiley, 2025)

  Purpose: To evaluate the diagnostic accuracy of Dual-Energy Computed Tomography (DECT) in distinguishing malignant from benign cervical lymph nodes in neck carcinoma based on iodine concentration and normalized spectral ...

• The mediating role of attachment in panic disorder and separation anxiety disorder 

  Baltacıoğlu, Mehmet; Çelik, Fatma Gül Helvacı; Puşuroğlu, Meltem (BioMed Central Ltd, 2025)

  Objective: This study aimed to investigate the mediating effect of attachment on the relationship between Panic Dısorder (PD) and Adult Separation Anxiety Disorder (ASAD). Methods: 76 patients with PD, who consecutively ...

• Alterations in tear function and meibomian gland dysfunction across various phenotypes of polycystic ovary syndrome 

  Sümer, Fatma; Gürlek, Beril; Yıldız, Elif; Uzun, Feyzahan; Çolak, Sabri (Nature Research, 2025)

  The aim of this study was to investigate the relationship between tear function changes and meibomian gland dysfunction in various phenotypes of polycystic ovary syndrome (PCOS). In this prospective case–control study, 4 ...

• A case-control study on the role of carbonic anhydrase autoantibodies in the pathogenesis and diagnosis of fibromyalgia 

  Kılıç, Hülya; Hasanova, Narmin; Topaloğlu, Mehmet Serhat; Şahin, Elif; Sağlam, Neslihan; Alemdar, Nihal Türkmen; Menteşe, Ahmet (Nature Research, 2025)

  To investigate the levels and diagnostic significance of carbonic anhydrase I (CAI) and II (CAII) autoantibodies and oxidative stress status in fibromyalgia syndrome (FMS) patients. A total of 59 FMS patients and 53 healthy ...

• Comprehensive αβ t-cell receptor repertoire analysis reveals a unique CD8+ TCR landscape in DOCK8-deficient patients 

  Bozkurt, Ceren; Çıldır, Gökhan; Aba, Ümran; Erdoğan, Rahmi Kutay; Warnock, Nicholas I; Kok, Chung Hoow; Sefer, Asena Pınar; Haskoloğlu, Şule; Tekeoğlu, Sidem Didar; Kılınç, Gülşah Merve; Ipşir, Canberk; Arıkoğlu, Tuğba; Özhan, Aylin Kont; Esenboğa, Saliha; Özen, Ahmet; Karakoç-Aydıner, Elif; Eltan, Sevgi Bilgiç; Aydogmuş, Çigdem; İslamoğlu, Candan; Baskın, Kübra; Karaatmaca, Betül; Metin, Ayşe; Çağdaş, Deniz; Doğu, Figen; İkincioğulları, Aydan; Barış, Safa; Erman, Baran (Wiley, 2025)

  Background: Dedicator of cytokinesis protein 8 (DOCK8) is a guanine nucleotide exchange factor highly expressed in, and critical for, the function of various innate and adaptive immune cells. DOCK8 deficiency leads to ...

• Could allopurinol be used in the treatment of schizophrenia? 

  Hocaoğlu, Çiçek (Medicinska Naklada Zagreb, 2025)

  ....

• Design, synthesis, and evaluation of benzimidazole-carbazole hybrids targeting heat shock proteins-mediated apoptosis in breast and colon cancer cells 

  Çapan, İrfan; Al, Mervenur; Gümüş, Mehmet; Açık, Leyla; Aydın, Betül; Çelik, Ayşe Büşranur; Gülüm, Levent; Sert, Yusuf; Yenilmez, Ezgi Nurdan; Koca, İrfan; Tutar, Yusuf (Wiley, 2025)

  Heat shock proteins (HSPs), particularly HSP70 and HSP90, are pivotal molecular chaperones implicated in cancer progression and resistance mechanisms. Dual inhibition of these chaperones represents a promising therapeutic ...

• The effectiveness of deep learning in the differential diagnosis of hemorrhagic transformation and contrast accumulation after endovascular thrombectomy in acute ischemic stroke patients 

  Beyazal, Mehmet; Solak, Merve; Tören, Murat; Asan, Berkutay; Kaba, Esat; Çeliker, Fatma Beyazal (MDPI (Multidisciplinary Digital Publishing Institute), 2025)

  Objectives: Differentiation of hyperdense areas on non-contrast computed tomography (NCCT) images as hemorrhagic transformation (HT) and contrast accumulation (CA) after endovascular thrombectomy (EVT) in acute ischemic ...

• Heart rate variability in children and adolescents with incidentally found early repolarization pattern 

  Arınç, Ahmet F.; Arıcı, Şule; Akalın, Figen (BioMed Central Ltd, 2025)

  Background: Early repolarization pattern (ERP) on electrocardiogram (ECG) was long considered benign, but recent data suggest a potential association with fatal arrhythmia and sudden cardiac death. Its relevance in pediatric ...

Daha Fazla