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Another side of lupus: A case report of lupus presenting with cutaneous vasculitis
(Wiley, 2023)
Systemic lupus erythematosus (SLE) is a systemic autoimmune complex disease that affects any organ, characterized by immune complex formation and autoantibody production. Lupus vasculitis begins at a young age. These ...
Asia-Pacific association for study of liver guidelines on management of ascites in liver disease
(Springer, 2023)
The development of ascites is a landmark event in the natural history of cirrhosis.
An international multidisciplinary consensus statement on MAFLD and the risk of CVD
(Springer, 2023)
Background Fatty liver disease in the absence of excessive alcohol consumption is an increasingly common condition with a global prevalence of similar to 25-30% and is also associated with cardiovascular disease (CVD). ...
A novel INPP4A mutation with pontocerebellar hypoplasia, myoclonic epilepsy, microcephaly, and severe developmental delay
(Elsevier, 2023)
Background: The inositol polyphosphate 4-phosphatase intracellular signaling pathway is susceptible to genetic or epigenetic alterations that may result in major neurological illnesses with clinically significant pons and ...
The development of ankylosing spondylitis in a patient with familial hemophilia
(Wiley, 2023)
Hemophilia is a rare inherited disease which causes bleeding due to Factor VIII or Factor IX deficiency. It is usually X-linked recessive and typically affects males. Arthropathy occurs as a result of cartilage damage and ...
Relationship between aeroallergen sensitization pattern and clinical features in adult asthmatics
(Elsevier, 2023)
Background: Asthma can be classified into atopic and non-atopic phenotypes. However, limited data are available on the clinical implications of these two phenotypes in real life. Objective: This study aimed to examine the ...
Editorial: "being normal weight each day keeps NAFLD and fibrosis away"-the importance of reducing cumulative exposure to overweight
(Wiley, 2023)
The obesity epidemic is globally driving the increased prevalence of non-alcoholic fatty liver disease (NAFLD), and the vast majority of patients with NAFLD are either overweight or obese.
Pathogenetic pathways in nonalcoholic fatty liver disease: An incomplete jigsaw puzzle
(Elsevier, 2023)
Multiple pathways including insulin signaling, JNK1/2 of MAPK signaling, GLP-1R signaling, and NRs affect to maintain the homeostasis of lipid metabolism in normal liver. ERK1/2 and P38 of MAPK signaling pathway antagonistically ...
Posterior longitudinal ligament suturation after lumbar discectomy provides postoperative a large intradural area: First report
(Wolters Kluwer Medknow Publications, 2023)
Background: Stability and flexibility of the spine are provided by the posterior longitudinal ligament (PLL). It plays a key role in the pathogenesis of lumbar disc herniation (LDH) by preventing disc protrusion. The effect ...
Impact of triple therapy on mortality in COPD
(European Respiratory, 2023)
Only a few therapies have been shown to prolong survival in specific patients with COPD. In recent years, the IMPACT and the ETHOS trials suggested that triple therapy (a combination of inhaled corticosteroid (ICS), ...