Ara
Toplam kayıt 29, listelenen: 1-10
Inhibiting renin angiotensin system in rate limiting step by aliskiren as a new approach for preventing indomethacin induced gastric ulcers
(Elsevier Ireland Ltd, 2016)
Purpose: Previously blocking the renin angiotensin system (RAAS) has been effective in the prevention of gastric damage. Therefore, the aim of this study was to investigate the effects of aliskiren, and thus, direct renin ...
Is there any correlation between levels of serum ostepontin, CEA, and FDG uptake in lung cancer patients with bone metastasis?
(Elsevier Espana Slu, 2016)
Objective: in this study, an evaluation was made of the relationship between the serum levels of carcinoembryonic antigen (CEA), osteopontin (OPN), and the semi-quantitative parameters of 18-fluoro2-deoxyglucose positron ...
A novel approach to contrast-induced nephrotoxicity: the melatonergic agent agomelatine
(British Inst Radiology, 2016)
Objective: To study the potential nephroprotective role of agomelatine in rat renal tissue in cases of contrast-induced nephrotoxicity (CIN). the drug's action on the antioxidant system and proinflammatory cytokines, ...
Effects of amlodipine on ischaemia/reperfusion injury in the rat testis
(Wiley, 2016)
The aim of this study was to examine the effects of amlodipine (AML) in rat testicular torsion/detorsion damage. in this study, rats were divided into eight groups: (i) sham; (ii) testicular ischaemia, 2h of ischaemia; ...
Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction
(Elsevier, 2021)
It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ...
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats
(Taylo & Francis Ltd., 2021)
Acute kidney injury (AKI) is observed in nearly 60% of patients undergoing cisplatin (CP) therapy. The aim of this study was to reveal the potential effects of apelin-13 (AP-13) in the prevention of CP-induced renal toxicity, ...
The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis
(Pergamon-Elsevier Science Ltd., 2021)
Aim: Early and prompt treatment of sepsis by effective antibiotics against susceptible organisms may be lifesaving. However, increased antibiotic resistance and side effects of chemotherapeutic agents limiting their ...
Bee pollen increases hippocampal brain-derived neurotrophic factor and suppresses neuroinflammation in adult rats with chronic immobilization stress
(Elsevier Ireland Ltd., 2021)
Chronic stress is a potential problem associated with anxiety, depression, and cognitive dysfunction. Bee pollen, a powerful antioxidant, has many therapeutic effects. In this study, we aimed to examine the effects of one ...
Can dexmedetomidine be effective in the protection of radiotherapy-induced brain damage in the rat?
(Springer, 2021)
Approximately 7 million people are reported to be undergoing radiotherapy (RT) at any one time in the world. However, it is still not possible to prevent damage to secondary organs that are off-target. This study, therefore, ...
Effects of gadodiamide and gadoteric acid on lung tissue: A comparative study
(Wiley, 2022)
We set out to investigate the effects of gadodiamide and gadoteric acid, used for magnetic resonance imaging, on the lungs. In this study, 32 male Sprague Dawley rats were used. These were allocated into four groups; The ...