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dc.contributor.authorKanburoğlu, Mehmet Kenan
dc.contributor.authorTayman, Cüneyt
dc.contributor.authorÖncel, Mehmet Yekta
dc.contributor.authorAkın, İlke Mungan
dc.contributor.authorCan, Emrah
dc.contributor.authorDemir, Nihat
dc.contributor.authorArayıcı, Sema
dc.contributor.authorBaser, Demet Orhan
dc.contributor.authorCaner, İbrahim
dc.contributor.authorMemişoğlu, Aslı
dc.contributor.authorUygun, Saime Sundus
dc.contributor.authorAkar, Selahattin
dc.contributor.authorAkın, Mustafa Ali
dc.contributor.authorAtaoğlu, Emel
dc.contributor.authorBezirganoğlu, Handan
dc.contributor.authorBilgin, Leyla
dc.contributor.authorBozdağ, Şenol
dc.contributor.authorCömert, Serdar
dc.contributor.authorGürpınar, Reşat
dc.contributor.authorİmamoğlu, Ebru Yalın
dc.contributor.authorİmdadoğlu, Timuçin
dc.contributor.authorNarter, Fatma
dc.contributor.authorÖzdemir, Ramazan
dc.contributor.authorToptan, Handan Hakyemez
dc.contributor.authorYalınbaş, Emine Esin
dc.contributor.authorYaman, Akan
dc.contributor.authorErdeve, Ömer
dc.contributor.authorKoç, Esin
dc.date.accessioned2020-12-19T19:32:20Z
dc.date.available2020-12-19T19:32:20Z
dc.date.issued2020
dc.identifier.citationKanburoglu, M. K., Tayman, C., Oncel, M. Y., Akin, I. M., Can, E., Demir, N., Arayici, S., Baser, D. O., Caner, I., Memisoglu, A., Uygun, S. S., Akar, S., Akin, M. A., Ataoglu, E., Bezirganoglu, H., Bilgin, L., Bozdag, S., Comert, S., Gurpinar, R., Imamoglu, E. Y., … Koc, E. (2020). A Multicentered Study on Epidemiologic and Clinical Characteristics of 37 Neonates With Community-acquired COVID-19. The Pediatric infectious disease journal, 39(10), e297–e302. https://doi.org/10.1097/INF.0000000000002862en_US
dc.identifier.issn0891-3668
dc.identifier.issn1532-0987
dc.identifier.urihttps://doi.org/10.1097/INF.0000000000002862
dc.identifier.urihttps://hdl.handle.net/11436/992
dc.descriptionCan, Emrah/0000-0002-2163-6564; Reis, AlessanRSS/0000-0001-8486-7469en_US
dc.descriptionWOS: 000573923900002en_US
dc.descriptionPubMed: 32932329en_US
dc.description.abstractBackground: Coronavirus disease 2019 (COVID-19) primarily affects adults and spares children, whereas very little is known about neonates. We tried to define the clinical characteristics, risk factors, laboratory, and imagining results of neonates with community-acquired COVID-19. Methods: This prospective multicentered cohort study included 24 neonatal intensive care units around Turkey, wherein outpatient neonates with COVID-19 were registered in an online national database. Full-term and premature neonates diagnosed with COVID-19 were included in the study, whether hospitalized or followed up as ambulatory patients. Neonates without severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) via reverse transcriptase-polymerase chain reaction testing or whose mothers had been diagnosed with COVID-19 during pregnancy were excluded. Results: Thirty-seven symptomatic neonates were included. the most frequent findings were fever, hypoxemia, and cough (49%, 41%, 27%, respectively). Oxygen administration (41%) and noninvasive ventilation (16%) were frequently required; however, mechanical ventilation (3%) was rarely needed. Median hospitalization was 11 days (1-35 days). One patient with Down syndrome and congenital cardiovascular disorders died in the study period. C-reactive protein (CRP) and prothrombin time (PT) levels were found to be higher in patients who needed supplemental oxygen (0.9 [0.1-8.6] vs. 5.8 [0.3-69.2]p= 0.002, 11.9 [10.1-17.2] vs. 15.2 [11.7-18.0]p= 0.01, respectively) or who were severe/critical (1.0 [0.01-8.6] vs. 4.5 [0.1-69.2]p= 0.01, 11.7 [10.1-13.9] vs. 15.0 [11.7-18.0]p= 0.001, respectively). Conclusions: Symptomatic neonates with COVID-19 had high rates of respiratory support requirements. High CRP levels or a greater PT should alert the physician to more severe disease.en_US
dc.description.sponsorshipTurkish Neonatal Societyen_US
dc.description.sponsorshipThe Turkish Neonatal Society funded the online registration system of the study. Funders had no role in study design, data collection, data analysis and interpretation, writing of the report, and decision to publish of the article. the corresponding author has full access to all the data in the study and takes final responsibility for the decision to submit for publication. All authors approved the final version of the manuscript. M.K.K. wrote the first draft of the manuscript, no honorarium, grant, or other form of payment was given to anyone to produce the manuscript. To the best of our knowledge, no conflict of interest, financial or other, exists. There are no prior publications or submissions with any overlapping information, including studies and patients.en_US
dc.language.isoengen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCoronavirus infectionsen_US
dc.subjectSARS-CoV-2en_US
dc.subjectCOVID-19en_US
dc.subjectNewbornen_US
dc.subjectAcute respiratory distress syndromeen_US
dc.titleA multicentered study on epidemiologic and clinical characteristics of 37 neonates with community-acquired COVID-19en_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.contributor.institutionauthorKanburoğlu, Mehmet Kenan
dc.identifier.doi10.1097/INF.0000000000002862
dc.identifier.volume39en_US
dc.identifier.issue10en_US
dc.identifier.startpageE297en_US
dc.identifier.endpageE302en_US
dc.relation.journalPediatric Infectious Disease Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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