Konu "Rat" için listeleme
Toplam kayıt 106, listelenen: 61-80
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Exogenous ATP administration prevents ischemia/reperfusion-induced oxidative stress and tissue injury by modulation of hypoxanthine metabolic pathway in rat ovary
(Univ Federal Santa Maria, 2014)In this study, xanthine oxidase (XO), malondialdehyde (MDA), myeloperoxidase (MPO) and glutathione (GSH) levels in the ovarian tissues of rats during the development of ischemia and postischemia-induced reperfusion were ... -
Gene expression and histopathological evaluation of thiamine pyrophosphate on optic neuropathy induced with ethambutol in rats
(Ijo Press, 2016)AIM: To compare the effects of thiamine pyrophosphate (TPP) and thiamine (TM) in oxidative optic neuropathy in rats induced by ethambutol. METHODS: the animals were divided into four groups: a control group (CG), an ... -
Hepatoprotective effect of punica granatum seed oil extract on paracetamol intoxication in rat via inhibory effect of CYP2E1
(2018)Punica granatum seed oil enriched by punikalagins has been shown to have a therapeutic effect against antidiabetic, anticancer, antiinflammatory and some organ toxicities. We aimed to reveal both protective and therapeutic ... -
Histological investigation of the effects of tenoxicam on pulmonary complications of pneumoperitoneum - Tenoxicam reduces lung injuries caused by pneumoperitoneum
(2011)Objectives. Pneumoperitoneum increases intra-abdominal pressure and generates oxidative stress, which mediates tissue injury. One of the causes of oxidative stress production is an inflammatory reaction. Taking this into ... -
Histopathological effects of intramuscular metamizole sodium on rat sciatic nerve
(Mashhad Univ Med Sciences, 2016)Objective(s): We investigated the histopathological effects of metamizole sodium (MS) on the sciatic nerve. Materials and Methods: This study was performed using 48 adult male Wistar albino rats. Ten groups were constituted ... -
Histopathological evaluation of the effects of dexmedetomidine against pituitary damage ınduced by X-ray irradiation
(Taylor & Francis Ltd., 2022)Background: The present study, aimed to investigate the potential negative effects of x-ray radiation and the effects of the α2-adrenergic receptor agonist dexmedetomidine on the pituitary gland. Methods: Twenty-four ... -
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
(Springer, 2024)Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ... -
The impact of resveratrol on oxidative stress induced by methotrexate in rat ileum tissue: evaluation of biochemical and histopathological features and analysis of gene expression
(Karger, 2016)Objective: the aim of this study was to assess the impact of resveratrol (RST) on oxidative stress induced by methotrexate in rat ileum tissue. Materials and Methods: Twenty-four rats were divided into 4 groups with 6 in ... -
The impaired balances of oxidant/antioxidant and COX-1/COX-2 in ovarian ischemia-reperfusion injury and prevention by Nimesulide
(Colegio Farmaceuticos Provincia de Buenos Aires, 2012)The aims of this study were to investigate the association of ovarian I/R injury with oxidant/antioxidant and cyclooxygenase activity and to examine the effect of nimesulide in I/R injury. Rats were divided into four groups: ... -
Investigating the effect of prunus laurocerasus fruit extract in type II diabetes induced rats
(Asian Network Scientific Information-Ansinet, 2013)Prunus laurocerasus (PL) is the fruits of the officinalis species in the Rosaceae family. It is used as diuretic, antidiabetic, antiulcer, dermatitis and hemorrhoids. This study investigate the antidiabetic effects of PL ... -
Investigation and histopathological evaluation of the effects of omeprazole on the ischemia-reperfusion induced oxidative damage and DNA mutation in rat ovarian tissue
(Chemical Publishing Co., 2013)In this study, the biochemical and histopathological effects of omeprazole on ischemia-reperfusion (I/R) induced oxidative damage in rat ovarian tissue were investigated. The moment that the animals remained motionless in ... -
Investigation of antiulcer and antioxidant activity of moclobemide in rats
(Aves, 2015)Amaç: Peptik ülser tedavisinde kullanılan çok sayıda klasik antiülser ilaç grupları bulunsa da, bu ilaçlar ile ülserin kalıcı tedavisi sağlanamamaktadır. 1950'den beri antidepresan ilaçlar non - psikiyatrik bazı hastalıkların ... -
The investigation of damage in the muscle tissue with the oxidant/antioxidant balance and the extent of postmortem DNA damage in rats
(2013)The relationship of the extent of DNA damage and certain components of the oxidant/antioxidant balance in rat femoral muscle tissue with the post-mortem intervals was investigated and examined by making direct comparison ... -
Investigation of mucus obtained from different fish species on the acute pain induced with scalpel incision in paw of rats
(Int Press Editing Centre Inc, 2016)No comparative study could be found for the analgesic activity of mucuses from the Oncorhynchus mykiss (OM), Salvelinus fontinalis (SF), Salmo coruhensis (SC), Acipenser gueldenstaedtii (AG), and Acipenserbaerii (AB) fish ... -
Investigation of the effect of the efficiency of noise at different intensities on the DNA of the newborns
(Medknow Publications & Media Pvt Ltd, 2016)Hearing loss can occur in newborns exposed to high-level noise; noise exposure can cause more physiological stress and can lead to DNA damage. This study was designed to determine DNA damage in newborn rats exposed to sound ... -
Investigation of the effectiveness of algan hemostatic agent in bleeding control using an experimental partial splenectomy model in rats
(Marmara Univ, Fac Medicine, 2019)Objective: Algan hemostatic agent (AHA) is a plant-based hemostatic agent produced in Turkey. Although, there is a great improvement in the hemostatic technologies, more effective hemostatic products are required to be ... -
Investigation of the effectiveness of plant based algan hemostatic agent in a rat model of femoral arterial bleeding
(Bezmialem Vakıf Üniversitesi, 2022)Objective: The aim of this study is to evaluate the efficacy of the Algan Hemostatic Agent (AHA) available in three different physical form (liquid, powder and sponge absorbed) in the femoral artery incision model in ... -
An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats
(Elsevier, 2019)Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ... -
An investigation of the effects of N-acetylcysteine on radiotherapy-induced testicular injury in rats
(Springer, 2019)According to data issued by the International Agency for Research on Cancer in 2012, the estimated number of new cases of all types of cancer worldwide was estimated to exceed 10 million, and 6 million of whom receive ... -
Long-term protective effects of lamotrigine in a rat ovarian ischemia-reperfusion model
(Elsevier, 2024)Ovarium torsion is a gynecological emergency that is common in women of reproductive age and requires early diagnosis and intervention. In this study, we aimed to investigate the long-term anatomical, histological and ...